DOI: https://doi.org/10.26641/2307-0404.2018.3(part1).142369

The role of clinical-functional research in case of pneumoconiosis associated with chronic obstructive pulmonary disease in workers of mining and metallurgical industry.

R. V. Rubtsov

Abstract


The purpose of the research is to study the features of clinical symptoms (using standard questionnaires),  the nature of external respiration disorders according to the spirometry indices in workers of mining and metallurgical industry with pneumoconiosis associated with COPD. The article presents the data of clinical examination of 634 workers with lung pathology of occupational etiology:  I group included 98 workers with pneumoconiosis associated with COPD, II group included 21 workers with pneumoconiosis, and III group – 515 workers with COPD of occupational etiology. A comparative analysis of clinical symptoms and external respiration function (ERF)  indicators was conducted. It has been revealed that for pneumoconiosis associated with COPD the most informative are indicators of Disease Assessment Test, exceeding 11 points, as well as spirometric volumetric and speed indicators of expiration, indicating combination of obstructive and restrictive disorders of ERF: lung vital capacity  (LVC) less than 67.0%, forced lung vital capacity  (FLVC) less than 60.0%, peak expiratory flow rate less than 40.0%, increase of the forced expiration volume (FEV1) index after the conducted (bronchodilation test) BDT less than 16.1%. The etiologic proportion of the influence of these indicators ranges from 40.5 to 71.6%, the sensitivity is from 0.22 to 0.39, the conditional possibility of occurrence is from 0.6 to 0.94, and the background capability is from 0.17 to 0.35. The revealed diagnostic criteria allow to carry out timely diagnostics, to determine treatment tactics and prevent PC associated with COPD in workers of mining and metallurgical industry.


Keywords


pneumoconiosis; chronic obstructive pulmonary disease; clinical features; external respiration function

References


Abrosimov VN. [Chronic obstructive pulmonary disease and pneumosclerosis as another phenotype]. Pulmonologiya. 2012;4:95-99. Russian.

Shpagina L, Poteryaeva EL, Kotova OS et al. [Ac­tual problems of pulmonology in modern occupational pa­thology]. Meditsina truda i promyshlennaya ekologiya. 2015;9:11-14. Russian.

Babkina VI, Bachinsky ON, Plemenova EYu. [Clinical aspects of pneumoconiosis and COPD in elderly and senile age]. Zhurnal fundamentalnyye issledovaniya. 2008;6:12-20. Russian.

Yelesevich SA, Razumov VV. [On pathogenetic unity of pneumoconiosis and dust bronchitis]. Meditsina truda i promyshlennaya ekologiya. 2007;2:28-32. Russian.

Krasnyuk OP, Tkach SI, Kovalchuk TA et al. [Application of pneumoconiosis classification in Ukraine: Guidelines]. Kyiv. 2002;15. Ukrainian.

Kundiev YuI, Basanets AV. [Pneumoconiosis: epi­demiology, early diagnostics, prevention]. Kyiv. 2012;192. Ukrainian.

Malashenko AV. [On the relationship between pneumoconiosis and dust bronchitis in the formation of lung pathology]. Meditsina truda i promyshlennaya ekologiya. 2006;1:22-26. Russian.

Plyukhin AE, Burmistrova ТP, Postnikova LV, Kovaleva AS. [Pneumoconiosis in modern industrial pro­duction]. Meditsina truda i promyshlennaya ekologiya. 2013;3:22-27. Russian.

[Order of the Ministry of Public Health of Uk­raine dated June 27, 2013 N 555 "On Approval and Im­plementation of Medical-Technological Documents for the Standardization of Medical Assistance in Case of Chro­nic Obstructive Pulmonary Disease]. Kyiv. 2013;146. Ukrainian.

[Guidance for assessing occupational health risks for workers. Organizational and methodological foundations, principles and criteria for evaluation. Rukovodstvo]. Moskva. 2003;24. Russian.

Global Initiative for Chronic Obstructive Lung Di­sease (GOLD). Pocket guide to COPD diagnosis, ma­nage­ment and prevention. [Internet]. 2017;14. http://www.gold­copd.org/uploads/-users/files/GOLD_Report_2017 Jan23.pdf.


GOST Style Citations


  1. Абросимов В.Н. Хроническая обструктивная болезнь легких и пневмосклероз – еще один фенотип / В.Н. Абросимов // Пульмонология. – 2012. – № 4. –  С. 95 – 99.
  2. Актуальные проблемы пульмонологии в со­вре­менной профпатологической практике / Л.А. Шпа­ги­на, Е.Л. Потеряева, О.С. Котова [и др.] // Медицина труда и промышленная экология. – 2015. – № 9. – С. 11-14.
  3. Бабкина В.И. Клинические аспекты пневмоко­ниоза и  ХОБЛ в пожилом и старческом возрасте / В.И. Бабкина, О.Н. Бачинский, Е.Ю. Племенова // Фун­даментальные исследования. – 2008. – № 6. – С. 12-20.
  4. Елесевич С.А. О патогенетическом единстве пневмокониозов и пылевого бронхита / С.А. Елесе­вич, В.В. Разумов // Медицина труда и промышленная экология. – 2007. – № 2. – С. 28-32.
  5. Застосування класифікації пневмоконіозів в Україні: метод. рекомендації / О.П. Краснюк, С.І. Ткач, Т.А. Ковальчук [та ін.] – Київ, 2002. – 15 с.
  6. Кундієв Ю.І. Пневмоконіоз: епідеміологія, ран­ня діагностика, профілактика / Ю.І. Кундієв, А.В. Басанець. – Київ: ВД «Авіцена», 2012. – 192 с.
  7. Малашенко А.В. О взаимосвязи пневмоко­ниоза и пылевого бронхита при формировании пато­логии легких / А.В. Малашенко // Медицина труда и промышленная экология. – 2006. – № 1. – С. 22-26.
  8. Пневмокониозы в условиях современных про­мышленных производств / А.Е. Плюхин, Т.П. Бур­ми­строва, Л.В.Постникова, А.С. Ковалева // Меди­цина тру­да и промышленная экология. – 2013. –№ 3. – С. 22-27.
  9. Про затвердження та впровадження медико-технологічних документів зі стандартизації медичної допомоги при хронічному обструктивному захво­рюванні легень: Наказ МОЗ України від 27 червня 2013 року № 555. – Київ, 2013. – 146 с.
  10. Руководство по оценке профессионального риска для здоровья работников. Организационно-ме­тодические основы, принципы и критерии оценки. Руководство: Р 2.2. 1766-03. − Москва: МЗ РФ, 2003. – 24 с.
  11. Global Initiative for Chronic Obstructive Lung Disease (GOLD). Poket guide to COPD diagnosis, ma­nagement and prevention 2017. Available at: http://www.goldcopd.org.




 

This work is licensed under a Creative Commons Attribution 4.0 International License