Features of diagnostics of gastroesophageal and duodenogastric reflux in patients with complicated forms of peptic ulcer.

Authors

DOI:

https://doi.org/10.26641/2307-0404.2018.4(part1).145659

Keywords:

duodenal ulcer, pH monitoring, impedance-pH monitoring, gastroesophageal reflux disease

Abstract

Purpose – to improve the results of surgical treatment of duodenal ulcer due to preoperative diagnosis of concomitant reflux disease and its correction. Before surgery, 46 patients with complicated forms of peptic  ulcer disease underwent pH monitoring and 23 – impedance-pH monitoring. Pathological gastroesophageal reflux was found in 58 cases. Before surgery, esophageal pH monitoring was performed in 46 patients with complicated forms of peptic ulcer disease. Against the background of hyper – and normacidity of the stomach in 39 patients pathological acidic gastroesophageal reflux disease with a significant increase of De Meester index was confirmed. Impedance-pH monitoring was performed before surgery in 23 patients with complicated forms of peptic ulcer and concomitant gastroesophageal reflux. Erosive form of gastroesophageal reflux disease was confirmed endoscopically in all patients with hyperacidity (17) and normal acidity (6) of the stomach. In 19 cases pathological gastroesophageal reflux disease was found. In 13 cases the cause of disorders in anti-reflux barrier was a diaphragmatic hernia of I-II degree. Gastroesophageal reflux disease was caused by increased intragastric pressure due to ulcer stenosis in 6 patients. pH- monitoring in patients with acidic gastroesophageal reflux allows to establish a pathological or physiological reflux. Conducting impedance-pH monitoring allows to determine the number of reflux episodes and their qualitative characteristics (acidic or alkaline; liquid, gas or mixed), as well as to determine the indications for a differentiated approach in the treatment of gastroesophageal reflux.

Author Biographies

N. N. Veligotskii

Kharkov Medical Academy of Postgraduate Education
Amosova str., 58, Kharkov, 61176, Ukraine

V. V. Komarchuk

Kharkov Medical Academy of Postgraduate Education
Amosova str., 58, Kharkov, 61176, Ukraine

E. V. Komarchuk

Kharkov Medical Academy of Postgraduate Education
Amosova str., 58, Kharkov, 61176, Ukraine

I. V. Teslenko

Kharkov Medical Academy of Postgraduate Education
Amosova str., 58, Kharkov, 61176, Ukraine

A. S. Chebotaryov

Kharkiv city clinical hospital of emergency medical care
lane of Balakirev 3А, Kharkov, 61000, Ukraine

References

Veligotskiy NN. [Modern organ-preserving me­thods in the surgery of bleeding and perforating ulcers (a tendency of the 21st century)]. Kharkov, S.A.M.;2015. Russian.

Trukhmanov AS, Kaybysheva VO, Storo­no­va OA, Ivashkin VT. [Intra-esophageal pH-impedance mea­surement in the diagnosis of gastroesophageal reflux disease]. Klinicheskie perspektivy gastroenterologii, ge­patologii. 2014;1:16-25. Russian.

Dorofeyev AE. [Diagnosis and treatment of di­gestive tract diseases]. Donetsk, Nord-Press; 2009. Russian.

Ivashkin VT, Maev IV, Trukhmanov AS. [Bar­rett's esophagus]. Moskva, Shiko; 2011. Russian.

Komarchuk VV. [Surgical treatment of a compli­cated ulcer disease in combination with gastroesophageal and duodenogastric reflux]. [dissertation]. Kharkov (UA), KhMAPO; 2016.

Mayev IV, Andreyev DN, Dicheva DT. [Gastro­esophageal reflux disease: from pathogenesis to thera­peutic aspects]. Consilium medicum. 2013;8(15):30-34. Russian.

Tsimmerman YaS. [Clinical gastroenterology]. Moskva, GEOTAR-Media; 2009. Russian.

Chernobrovyi VV. [Express-gastro-pH-monito­ring - a method of studying acid-forming function of the stomach]. Svit medycyny ta biologii. 2007;3:85-90. Ukrainian.

Ravi K, Katxka DA. Esophageal impedance mo­nitoring: Clinical pearls and pitfalls. The American Journal of Gastroenterology. 2016;111:1245-56.

How to Cite

1.
Veligotskii NN, Komarchuk VV, Komarchuk EV, Teslenko IV, Chebotaryov AS. Features of diagnostics of gastroesophageal and duodenogastric reflux in patients with complicated forms of peptic ulcer. Med. perspekt. [Internet]. 2018Dec.3 [cited 2024Apr.25];23(4(part1):36-4. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/145659

Issue

Section

CLINICAL MEDICINE