The use of procalcitonin in patients with surgical forms of erysipelas

Authors

  • S.D. Shapoval SI «Zaporizhzha Medical Academy of post-graduate education Ministry of Health of Ukraine», Institute of Sepsis, Wintera blvd., 20, Zaporizhzhia, 69096, Ukraine, Ukraine https://orcid.org/0000-0001-8516-9494
  • L.A. Vasylevska SI «Zaporizhzha Medical Academy of post-graduate education Ministry of Health of Ukraine», Institute of Sepsis, Wintera blvd., 20, Zaporizhzhia, 69096, Ukraine, Ukraine https://orcid.org/0000-0002-0607-5279

DOI:

https://doi.org/10.26641/2307-0404.2021.1.228011

Keywords:

procalcitonin, surgical forms of erysipelas

Abstract

The ideal marker of bacterial infection should not only allow for early diagnosis, but also provide information about the course and prognosis of the disease. Nowadays the most well-studied and widely used in clinical practice is procalcitonin (PCT), but its value in surgical forms of erysipelas is insufficiently defined. The aim of the article is to determine the diagnostic and prognostic significance of procalcitonin in patients with surgical forms of erysipelas.114 case histories of patients who were hospitalized in the center of purulent-septic surgery of the Non-profit municipal enterprise "City Hospital №3" in Zaporozhye for 2019-2020 period were analyzed retrospectively and prospectively. It was found that most often the focus was localized on the lower extremities. In the complex treatment of patients with erysipelas, the main place belongs to antibiotic therapy (ABT) and early surgical treatment of the area of the pathological process. Determination of the level of procalcitonin in the serum makes it possible to assess the progression and generalization of the process and is a sensitive test for the effectiveness of treatment.Radical surgery and timely targeted ABT are key elements of success in the treatment of surgical forms of erysipelas and are not subject to revision. Procalcitonin is a diagnostic marker that can predict the development of sepsis.

References

Gopatsa GV, Yermakova LA. [Erysipelas: current state of the problem]. Nauchnyi almanakh. 2016;1-2:364-41. Russian.

Gostishchev VK, Lipatov KV, Komarova YEA. [Streptococcal infection in surgery]. Khirurgiia. Zhurnal im. NI Pirogova. 2015;12:14-7. Russian. doi: https://doi.org/10.17116/hirurgia20151214-17

Polyakova AS, et al. [The diagnostic value of determining the level of procalcitonin in the practice of an infectious disease specialist]. Voprosy sovremennoi pediatrii. 2017;16:334-41. Russian. doi: https://doi.org/10.15690/vsp.v16i4.1781

[Electronic textbook on statistics]. [Internet]. [cited 2019 July 01]. Ukrainian. Available from: http://statsoft.ru/home/textbook/default.htm

Ratnikova LI, et al. [Comorbidity of erysipelas and endocrine diseases]. Nauchnyi almanakh. 2016;3:341-6. Russian. doi: https://doi.org/10.17117/na.2016.05.03.341

Vitik AA, et al. [Predictors of the development of sepsis and septic shock]. Vestnik intensivnoi terapii. 2017;3:63-8. Russian. Available from: https://intensive-care.ru/prediktory-razvitiya-sepsisa-i-septicheskogo-shoka/

Seymour CW, Liu V, Iwashyna TJ, et al. Assessment of clinical criteria for sepsis. JAMA. 2016;315(8):762-44. doi: https://doi.org/10.1001/jama.2016.0288

Bruun Т. Early response in cellulitis: a prospective study of dynamics and predictors. Clinical Infectious Diseases. 2016;63(8):1034-41. doi: https://doi.org/10.1093/cid/ciw463

De Jong JA, Van Oers А. Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial. The Lancet Infectious Diseases. 2016;7:1-9.

doi: https://doi.org/10.1016/S1473-3099(16)00053-0

Falconeet М. Acute bacterial skin and skin structure infection sininternal medicine wards: old and new drugs. Internaland Emergency Medicine. 2016;11(5):637-48.

doi: https://doi.org/10.1007/s11739-016-1450-6

Milcent K. Use of Procalciton in Assaysto Predict Serious Bacterial Infectionin Young Febrile Infants. JAMA Pediatr. 2016;170(1):62-69. doi: https://doi.org/10.1001/jamapediatrics.2015.3210

Singer M. Third International Consensus Definitions for Sepsis and Septic Shock). JAMA. 2016;315(8):801-10. doi: https://doi.org/10.1001/jama.2016.0287

Rhodes A, Evans LE, Alhazzani Waleed, Mitchell M Levy, Massimo A, Ferrer R., et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med. [Internet]. 2017 Mar;43(3):304-77. doi: https://doi.org/10.1007/s00134-017-4683-6

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Published

2021-03-26

How to Cite

1.
Shapoval S, Vasylevska L. The use of procalcitonin in patients with surgical forms of erysipelas. Med. perspekt. [Internet]. 2021Mar.26 [cited 2024Apr.25];26(1):196-200. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/228011

Issue

Vol. 26 No. 1 (2021)

Section

CLINICAL MEDICINE

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