Heritability of body mass index and physical activity in Ukrainian adolescents

Authors

DOI:

https://doi.org/10.26641/2307-0404.2022.4.271223

Keywords:

adolescents, physical activity, body mass index, heritability, familial aggregation

Abstract

The article analyzed the lifestyle and physical development of Ukrainian adolescents and their parents and estimated the familial aggregation and heritability of body mass index and physical activity. 408 nuclear families were examined (1216 people with complete information).  Anthropometric measures such as weight, height were measured following standardized procedures of WHO. Questionnaires were used to estimate the levels of physical activity. The method of genetic epidemiology research was used to explore heritability (h2) and family aggregation (ρ). Analysis was performed using the software product S.A.G.E. The study showed that 12.0±1.6% of children were overweight or obese, 6.4±1.2% were underweight and 81.6±1.9% with normal weight. It was found that among adolescents aged 12-15 years, 17.5±3.1% of boys and 32.7±2.9% of girls were physically inactive. Body mass index values higher than 25.0 kg/m2 were found in 34.3±2.4 mothers and in 70.6±2.3% of fathers. The proportion of physically inactive persons was 45.7±2.5% among mothers and 51.1±2.7% among fathers. Heritability values were significant for both body mass index (h2 =0.41±0.09; p<0.001) and physical activity (h2 =0.23±0.07; p<0.001). Significant familial correlations were obtained between parents-offspring for physical activity (ρ=0.20±0.04; p<0.001) and body mass index (ρ=0.25±0.03; p<0.001). The study estimated that the familial correlations for physical activity between mother-son and mother-daughter pairs were higher than in father-son and father-daughter pairs. The highest is the mother-daughter aggregation (ρ = 0.29 ± 0.06; p <0.001), the lowest is the father-son (ρ=0.19±0.08; p<0.05) by body mass index. As physical inactivity and overweight increase the risk of non-communicable diseases development, the data obtained should be taken into account while planning preventive measures.

References

Roth GA, Mensah GA, Johnson CO, et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019. Update From the GBD 2019 Study. J Am Coll Cardiol. 2020 Dec 22;76(25):2982-3021. doi: https://doi.org/10.1016/j.jacc.2020.11.010

Dempsey PC, Matthews CE, Dashti SG, et al. Sedentary Behavior and Chronic Disease: Mechanisms and Future Directions. J Phys Act Health. 2020 Jan 1;17(1):52-61. doi: https://doi.org/10.1123/jpah.2019-0377

World Health Organization. The impact of the COVID-19 pandemic on noncommunicable disease resources and services: results of a rapid assessment. World Health Organization [Internet]; 2020. Available from: https://apps.who.int/iris/handle/10665/334136.

Andrieieva O, Kashuba O, Yarmak O, et al. Ef-ficiency of children's fitness training program with elements of sport dances in improving balance, strength and posture. Journal of Physical Education and Sport. 2021;21(5):2872-9. doi: https://doi.org/10.7752/jpes.2021.s5382

Che WI, Westerlind H, Lundberg IE, et al. Fami-lial aggregation and heritability: a nationwide family-based study of idiopathic inflammatory myopathies. Ann Rheum Dis. 2021 Nov;80(11):1461-6. doi: https://doi.org/10.1136/annrheumdis-2021-219914

Barbosa J, Basso L, Bartholomeu T, et al. Familial aggregation and heritability of markers of metabolic risk, physical activity, and physical fitness in nuclear families from Muzambinho (Minas Gerais, Brazil). Arch Endocrinol Metab. 2019 May-Jun;63(3):215-21. doi: https://doi.org/10.20945/2359-3997000000137

Blomquist GE. Unpacking the heritability of body mass index and other ratios. Am J Hum Biol. 2019 Sep;31(5):e23289. doi: https://doi.org/10.1002/ajhb.23289

Bull FC, Al-Ansari SS, Biddle S, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020 Dec;54(24):1451-62. doi: https://doi.org/10.1136/bjsports-2020-102955

Piercy KL, Troiano RP, Ballard RM, et al. The Physical Activity Guidelines for Americans. JAMA. 2018 Nov 20;320(19):2020-8. doi: https://doi.org/10.1001/jama.2018.14854

Yelizarova O, Stankevych T, Parats A, et al. Specific Features of the Ukrainian Urban Adolescents' Phy-sical Activity: A Cross-Sectional Study. J Environ Public Health. 2020 Apr 9;2020:3404285. doi: https://doi.org/10.1155/2020/3404285

Bouchard C, Malina RM, Pérusse L. Genetics of Fitness and Physical Performance. Champaign, IL: Human Kinetics; 1997.

Lezhenko G. [Features of obesity in adolescents]. Dytiachyi likar. 2017;1(52):20-26. Ukrainian. Available from: https://d-l.com.ua/uploads/issues/2016/2(47)/DL16-2_20-26_b71a6779e2e6263607fd9f142171edcf.pdf.

Lembryk I, Cycjura O, Pryjmak R. [Clinical course and prevalence of obesity in combination with Oddi's sphincter dysfunction in adolescents]. Child`s health. 2019;14(3):159-64. Ukrainian. doi: https://doi.org/10.22141/2224-0551.14.3.2019.168767

Ogniev VA, Pomohaibo KG. [Medico-social sub-stantiation of the model of quality management of obesity of children]. Visnyk socialnoi hihiieny ta organizatsii ohorony zdorovia Ukrainy. 2018;1(75):52-60. Ukrainian. Available from: http://repo.knmu.edu.ua/handle/123456789/21046

Sorokman TV, Popeliuk OM, Ushakova KJu. [Prognostic criteria for the development of metabolic syndrome in children]. Child`s health. 2016;2:29-32. Ukrainian. Available from: http://nbuv.gov.ua/UJRN/Zd_2016_2_6

Published

2022-12-29

How to Cite

1.
Omelchenko E, Yelizarova O, Polka N, Polka O, Hozak S. Heritability of body mass index and physical activity in Ukrainian adolescents. Med. perspekt. [Internet]. 2022Dec.29 [cited 2023Jun.9];27(4):192-9. Available from: http://journals.uran.ua/index.php/2307-0404/article/view/271223

Issue

Section

PREVENTIVE MEDICINE

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