Analysis of pregnancy and childbirth course in pregnant women with excessive weight.

Authors

  • Yu. M. Duka

DOI:

https://doi.org/10.26641/2307-0404.2015.1.40303

Keywords:

pregnancy, obesity, pregnancy losses, hyper coagulation

Abstract

Under supervision there were 233 pregnant women with excessive weight aged 18-43 years. Patients were under observation and gave birth on the basis of obstetric units of municipal establishment "Dnepropetrovsk regional perinatal center with in-patient unit of" Dnepropetrovsk regional council". When performing research 2 groups were formed: 120 (51,5%) pregnant women with miscarriage threat against excessive weight being at in-patient treatment since early terms of pregnancy. They underwent in-depth study. 113 (48,5%) pregnant women with obesity with gestation course estimated retrospectively at the time of delivery. As a result of the obtained data in women of prospective group treatment algorithm was developed. This algorithm represented a complex treatment including antiagregant and anticoagulant therapy, co-factor vitamin therapy. Despite a more mature age of women of prospective group, adverse anamnesis by missarriage, high frequency of  miscarriage in its first half, low placentation level, this complex allowed to improve course of the second half of pregnancy and to reduce number of gestational complications and perinatal losses.

Author Biography

Yu. M. Duka

SE "Dnipropetrovsk medical academy of Health Ministry of Ukraine"
Department of Obstetrics, Gynecology and Perinatology
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

References

Makarov IO, Borovkova I, Bairamova MYu. [Course of pregnancy and labor in patients with obesity]. Akusherstvo, ginekologija i reprodukcija. 2014;1:60-67. Russian. 2. Makatsariya AD, Bitsadze VO, Akin'shina SV. [A syndrome of system inflammatory answer in obstetrics]. Moscow. 2006;448. Russian. 3. Makatsariya AD, Pshenichnikova EB, Pshe¬nich¬ni¬kova TB, Bitsadze VO. [Metabolic syndrome and throm¬bophilia in obstetrics and gynecology]. Moscow. 2006;480. Russian. 4. Roitberg GE. [Metabolic syndrome]. Moscow. 2007;224. Russian. 5. Belyakov NA, Seidova GB, Chubrieva SYu, Glukhov NV. [Metabolic syndrome in women (pathophy¬siology and clinical picture)]. St. Petersburg. 2005;438. Russian. 6. Rebrova OYu. [Statistical analysis of medical data. Application of software package STATISTICA]. Mos¬cow. 2002;312. Russian. 7. Makatsariya AD, Bitsadze VO, Baimuradova SM, Akin'shina SV, Panfilova OYu, Mishchenko AL, Perederyaeva EV, Pshenichnikova TB, Khizroeva VKh. [Systemic syndromes in obstetric practice]. Moscow. 2010;888. Russian. 8. Donath M, Schnetzier M, Ellingsgaard H, et al. Cytokine production by islets in health: cellular origin, regulation and function. Trends Endocrinol Metab. 2010;21(5):261-7. 9. Palomo I, Alarcon M, Moore-Carrasco R, et al. Hemostasis alterations in metabolic syndrome. Interna¬tional Journal of Molecular Medicine. 2006;18:969-74. 10. Lakshmy R. Metabolic syndrome: role of ma¬ternal undernutrition and fetal programming. Rev Endocr Metab Disord. 2013;14(3):229-40. 11. Madan JC, Davis JM, Creig WY, et al. Maternal obesity and markers of inflammation in pregnancy. Cy¬tokine. 2009;47(1):61-4. 12. Horvath B, Bodecs T, Boncz I, et al. Metabolic syndrome in normal and complicated pregnancies. Metab Syndr Relat Disord. 2013;11(3):185-8. 13. Pou KM, Massaro JM, Hoffman UN. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation. 2007;16(11):1234-41.

Downloads

Published

2015-03-16

How to Cite

1.
Duka YM. Analysis of pregnancy and childbirth course in pregnant women with excessive weight. Med. perspekt. [Internet]. 2015Mar.16 [cited 2024Apr.20];20(1):55-62. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/40303

Issue

Section

CLINICAL MEDICINE