Features of cerebral blood flow, cardiac arrhythmias and conduction disturbances in patients with essential hypertension stage II associated with occlusive and stenotic lesions of brachiocephalic arteries.

Authors

  • V. A. Vizir
  • V. V. Shkolovоy

DOI:

https://doi.org/10.26641/2307-0404.2015.3.52746

Keywords:

hypertension, occlusive-stenotic lesions of brachiocephalic arteries, cerebral blood flow asymmetry, linear velocity of blood flow, cardiac arrhythmias and conduction disturbances

Abstract

Arterial hypertensionis the most common disease of the cardiovascular system in industrially advanced countries. With the aim to determine the characteristics of cerebral blood flow, disorders of cardiac rhythm and conduction in patients with stage 2 hypertension associated with stenotic and occlusive lesions of brachiocephalic arteries, cerebral blood flow indicators were studied in 87 patients using duplex scanning of extracranial arteries and Holter ECG monitoring. It was established that linear blood flow velocity was considerably decreased in the basins of the internal and common carotid artery; cerebral blood flow asymmetry was present in the course of the internal carotid artery. Evidence-based differences in structure of arrhythmias were revealed by single and paired ventricular extrasystoles, as well as episodes of unstable ventricular tachycardia. All this indicates the progressive decrease of elasticity and tonicity of vessel walls, intensified rigidity and sinuosity of carotid arteries, more severe disorders of cardiac rhythm and conduction in case of simultaneous hypertension and atherosclerotic lesion of brachiocephalic arteries.

Author Biographies

V. A. Vizir

Zaporizhzhya State Medical University
Chair of Internal Diseases 2
Mayakovsky av., 26, Zaporizhzhya, 69035, Ukraine

V. V. Shkolovоy

Zaporizhzhya State Medical University
Chair of Internal Diseases 2
Mayakovsky av., 26, Zaporizhzhya, 69035, Ukraine

References

Gorbas' ІМ. [The epidemiology of major risk factors for cardiovascular disease]. Arterial'naya giper¬tenziya. 2008;2:13-18. Ukrainian. 2. Zharinov OJ. [Holter monitoring of electrocar¬diogram: the evolution of clinical use, diagnostic pos¬sibilities, indications]. Ukraїns'kiy kardіologіchniy zhur¬nal. 2004;1:122-7. Ukrainian. 3. Iskenderov BG, Vakina TN, Shibaeva TM. [The frequency and nature of arrhythmias and conduction di¬sorders of the heart in patients with different clinical and pathogenetic variants of hypertension]. Klynycheskaja medycyna. 2004;8:21-24. Russian. 4. Kovalenko VM. [Hypertension guide]. MORION. 2010;262-9. Ukrainian. 5. Kovalenko VM. [Cardiovascular diseases. The clas¬sification, standards for diagnosis and treatment]. Biznes Poligraf. 2007;128. Ukrainian. 6. Kondratjuk VJe, Jena LM. [Age features of struc¬tural and functional state of the heart and arteries of elastic type, systemic hemodynamics, myocardial bio¬electrical activity in hypertensive patients]. Zhurnal AMN Ukrai'ny. 2009;15(1):98-115. Ukrainian. 7. Kondratjuk VJe. [Sex differences in structural and functional state of the heart and vascular system and intracardial hemodynamics of bioelectrical activity and myocardium homogeneity in hypertensive patients with concomitant elderly type 2 diabetes]. Problemі stareniya i dolgoletiya. 2009;18(2):210-22. Russian. 8. Maslyaeva LV, Reznik LA, Koval' SN. [Features of the heart and blood vessels remodeling in patients with hypertension and type 2 diabetes]. Ukrainskiy tera¬pevticheskiy zhurnal. 2005;3:62-66. Russian. 9. Sirenko YuN. [Hypertensive disease and arterial hypertension]. Izdatel' Zaslavskiy AYu. 2011;288. Russian. 10. Halafjan AA. [STATISTICA 6. Statistical ana¬lysis of data: text book]. Binom-Press. 2007;512. Russian. 11. 2007 Guidelines for the management of arterial hypertension. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur.Heart J. 2007;28:1462-536. 12. Aaslid R. Cerebral hemodynamics. In Newell DW, Aaslid R, editors. Transcranial Doppler. New York: Raaven; 1992;500. 13. Ferrario CM, Strawn WB. Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular disease. Am J Cardiol. 2006;98 (1):121-8. 14. Vester EG. Arterial hypertension and cardiac arrhythmias. Dtsch. Med. Wochenschr. 2008;133(8):261-5. 15. Yiu KH, Tse HF. Hypertension and cardiac arrhythmias: a review of the epidemiology, pathophysiology and clinical implications. J. Hum. Hypertens. 2008;22(6):38.

Downloads

Published

2015-09-23

How to Cite

1.
Vizir VA, Shkolovоy VV. Features of cerebral blood flow, cardiac arrhythmias and conduction disturbances in patients with essential hypertension stage II associated with occlusive and stenotic lesions of brachiocephalic arteries. Med. perspekt. [Internet]. 2015Sep.23 [cited 2024Mar.28];20(3):15-21. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/52746

Issue

Section

CLINICAL MEDICINE