DOI: https://doi.org/10.26641/2307-0404.2016.1.63486

Gender peculiarities of cardiac performance in children with bronchial asthma.

V. A. Kondratiev, A. V. Reznik

Abstract


By the data of clinical-instrumental examination there was performed comparative assessment of gender differences in cardiac performance of 54 patients aged 5-15 years with persisting form of partially controlled atopic bronchial asthma in inter-attack period of disease. Children were divided in two groups depending on gender - 28 boys and 26 girls. Group of comparison included 52 healthy children - 26 girls and 26 boys. Inthegirlsinthe inter-attackperiodofasthmareliablymoreoftenthanintheboystherewererevealedventilationdisturbanceinthelungsbyobstructivetype; thispromotedriseofpressureinthepulmonary artery. Herewith only in girls in 15,4% of cases there was revealed arterial pulmonary hypertension of a mild form. By the data of echocardiography in girls with bronchial asthma as compared with boys more expressed dilatation both of the right and left ventricles of the heart was observed.Average means of left ventricle contractility both in girls and boys in the inter-attack period of bronchial asthma were reliably decreased (р<0,01) as compared with healthy children, but in girl-patients as compared with boys these deviations were more significant. In the majority of such cases (in girls – 73,9%, in boys – 53,8%) decrease of contractile myocardium function was caused by presence of metabolic disorders in the form of repolarization changes of ventricular complex ob electrocardiogram. Investigations performed showed presence of some gender differences in cardiac performance in bronchial asthma children which should be considered in the course of treatment.


Keywords


children; cardio-vascular system; gender differences; bronchial asthma

Full Text:

PDF

References


Poll L Allana, Poll А Dabbinsa, Myrona А Po-zyaka, V Normana Маk Dikena. [Clinical Doppler ultrasonography]. Lviv: Medycyna svity, 2007;374. Ukrainian. 2. Lyzohub VH, Altunina NV, Bоndarchuk ОМ. [Gender-sensitive use of amlodipine in patients with asthma]. Astma ta alergiya. 2010;3-4:37-40. Ukrainian. 3. Pechkurov DV, Voronina ЕN, Poreckova GYu. [Features of physical development, feeding behavior, and quality of life for children with asthma]. Prakticheskaya medicina. 2013;76(6):122-6. Russian. 4. Rybakova MК, Alyohin MN, Mitkov VV. [A practical guide to ultrasound diagnostics. Echocar¬dio-graphy]. M.: Izdat. dom «Vidar-M», 2008;512. Russian. 5. Fridman IL. [The impact of gender differences on the course of bronchial asthma]. Каzanskiy me-dicinskyi zhurnal. 2010;91(5):603-6. Russian. 6. Yunkerov VI, Grigoryev SG. [Mathematical and statistical processing of medical research]. SPb.: VMedА, 2002;266. Russian. 7. Warnier MJ, Rutten FH, Kors JA et al. Cardiac arrhythmias in adult patients with asthma. Journal of Asthma. 2012;49(9):942-5. 8. GINA REPORT, Global Strategy for Asthma Management and Prevention. revised. 2014;1-132. 9. Schatz M, Camargo CA. The relationship of sex to asthma prevalence, health care utilization, and me-dications in a large managed care organization. Ann Allergy Asthma Immunol. 2003;91:553-4. 10. Yiallouros PK, Economou M, Kolokotroni O, Savva SC et al. Gender differences in objectively assessed physical activity in asthmatic and non-asthmatic children. Pediatr. Pulmonol. 2015;50(4):317-26.


GOST Style Citations


1. Клінічна допплерівська ультрасонографія / за ред. Пола Л. Аллана, Пола А. Даббінса, Мирона А. По¬зняка, В. Нормана МакДікена [пер. з англ.]. - Львів: Медицина світу, 2007. - 374 с. 2. Лизогуб В.Г. Гендерні особливості застосу-вання амлодипіну у хворих на бронхіальну астму/ В.Г. Лизогуб, Н.В. Алтуніна, О.М. Бондарчук // Астма та алергія.-2010.-№3-4.-С.37-40. 3. Печкуров Д.В. Особенности физического раз-вития, пищевого поведения и качества жизни детей с бронхиальной астмой / Д.В. Печкуров, Е.Н. Воронина, Г.Ю. Порецкова // Практическая медицина. - 2013.-Т. 76, № 6. – С. 122-126. 4. Pыбaкoва M. К. Пpaктичeскoe pyкoвoдствo пo yльтpазвyкoвoй диaгнoстикe. Эxoкapдиoгpафия / M. К. Pыбaкoва, M.H. Aлexин, B.B. Mитькoв // Mосква: Издaт. дoм «Bидap-M», 2008. – 512 c. 5. Фридман И.Л. Влияние гендерных различий на особенности течения бронхиальной астмы / И.Л. Фридман // Казан. мед. журнал. – 2010. – Т. 91, № 5. – С. 603-606. 6. Юнкеров В.И. Математико-статистическая об¬работка данных медицинских исследований / В.И. Юн¬керов, С.Г. Григорьев.– СПб.: ВМедА, 2002.- 266 с. 7. Cardiac arrhythmias in adult patients with asthma/ M.J.Warnier, F.H.Rutten, J.A.Kors [et al.] // J. Asthma.-2012.-Vol.49, N9.-P.942-945. 8. GINA REPORT, Global Strategy for Astma Ma-nagement and Prevention/ revised 2014. – P. 1-132. 9. Schatz M. The relationship of sex to asthma pre-valence, health care utilization, and medications in a large managed care organization/M.Schatz, C.A.Camargo // Ann Allergy Asthma Immunol. – 2003. – Vol. 91. – P. 553-554. 10. Yiallouros P.K. Gender differences in objecti¬vely assessed physical activity in asthmatic and non-asthmatic children / P.K. Yiallouros, M. Economou, O. Kolokotroni, S.C. Savva [et al.] // Pediatr. Pulmonol. – 2015. – Vol. 50, N 4. – P. 317-326.




 

This work is licensed under a Creative Commons Attribution 4.0 International License