DOI: https://doi.org/10.26641/2307-0404.2016.2.71751

Morphology of embryonic liver under the influence of silver and gold citrates on a background of lead intoxication.

V. I. Harets, V. F. Shatorna, Iu. O. Belska

Abstract


Morphological state of embryonic liver under the influence of silver and gold citrates on a background of lead intoxication was studied. We found that  values of the hepatofetal index in the groups Pb+Ag and Pb+Au had significant differences as compared to the group exposed to lead intoxication, but did not differ significantly from the control group and made up 0,086±0,001 and 0,083±0,001, respectively. Value of the relative area of blood vessels in groups Pb+Ag and Pb+Au was 13.08±0.53% and 16.83±0.53%, respectively, which had no significant difference as compared to control group, but differed from the value of lead intoxication group. Under the influence of silver citrate on a background of lead intoxication the relative area of hematopoietic cells was 52,5±0,95%; this indicates to modification action of silver on haematopoiesis. Thus, injection of silver and gold citrates prevents negative effect of lead on morphometric parameters of embryonic liver, relative area of blood vessels and hematopoietic cells. Experiment results showed protective effect of silver and gold citrates on a background of lead intoxication during hepatogenesis.


Keywords


embryonic liver; lead acetate; silver citrate; gold citrate

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Cited-by:

1. INFLUENCE OF HEAVY METALS ON THE MORPHOFUNCTIONAL STATE OF THE LIVER (REVIEW OF LITERATURE)
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Bulletin of Problems Biology and Medicine  Vol: 1.2  Issue: 144  First page: 27  Year: 2018  
doi: 10.29254/2077-4214-2018-1-2-143-27-30



 

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