DOI: https://doi.org/10.26641/2307-0404.2016.3.82013

Features of the cardiovascular system in patients with type 1 diabetes.

N. O. Pertseva, K. I. Moshenets

Abstract


Lesion of the cardiovascular system in diabetes is the leading cause of mortality in this cohort of patients, it is of particularl importance because current approaches to the treatment of type 1 diabetes and existing insulins allow patients to live to the elderly age and have significant experience of type 1 diabetes. The development of new approaches to the early detection of disorders of the cardiovascular activity in preclinical stage will prevent or delay such dangerous consequences as fatal ventricular arrhythmias, silent myocardial infarction, cardiorespiratoryarrest, sudden death and will improve quality of life. In this review article aggregate data on the mechanisms of formation, provoking factors and manifestations of cardiovascular disorders in type 1 diabetes as well as possibility of correcting these changes, especially in the long course of diabetes are presented.


Keywords


type 1 diabetes; cardiac arrhythmias; hypertension; orthostatic hypotension; diastolic dysfunction

Full Text:

PDF

References


Ametov AS, Lysenko MA. [Type 2 diabetes and cardiovascular disease: a clash of two global epidemics]. Russkiy Meditsinskiy Zhurnal. 2011;19(13):802-4. Russian.

Ananieva SA. [The role of alpha-lipoic acid in the treatment of diabetic polyneuropathy]. Lechashchiy vrach. 2013;11:92-94. Russian.

Aronov DM, Lupanov VP. [Functional tests in cardiology]. 3nd.ed. Moscow: MEDpress inform. 2007;328. Russian.

Akhmedzhanova LT. [Diabetic neuropathy: from the variety of clinical forms to treatment]. Effektivnaya farmakoterapiya. Nevrologiya. 2009;23(3):53. Russian.

Balabolkin MI, Klebanov EM, Kreminskaya VM. [Differential diagnosis and treatment of endocrine di-seases]. Moscow: MIA. 2008;752. Russian.

Valeeva FV, Shaydullina MR. [Diagnosis of dia-betic cardiac autonomic neuropathy in patients with type 1 diabetes]. Sakharnyy diabet. 2009;4:56-59. Russian.

Dedov II, Shestakova MV. [Standards of spe¬cia-lized diabetes care (7th edition)]. Diabetes. 2015;18(1S):112. Russian.

Laptev DN, Kuraeva TL, Ryabykina GV, Po¬lya-kov SD, Korneeva IT, Namazova-Baranova LS. [Diag-nostic significance of asymptomatic ST segment dep-ression during exercise testing in children and adolescents with type 1 diabetes mellitus and autonomic neuropathy]. Sakharnyy diabet. 2015;18(2):54-60. Russian.

Zinov'eva OE. [The preparations of alpha-lipoic acid in diabetic neuropathy treatment]. Klinicheskaya meditsina. 2009;1:58-62. Russian.

Kadzharyan VG, Solov'yuk AO, Bidzilya PP. [Dia¬betic neuropathy: classification and diagnosis]. Zaporozhskiy meditsinskiy zhurnal. 2010;12(4):108-14. Russian.

Kravchun NA. [The autonomic diabetic neuro-pathy]. Zdorov'e Ukrainy. 2010;1:29. Russian.

Kurnikova IA, Chernyshova TE. [A blood pres-sure variability in the clinical expert diagnosis of diabetes]. Arterial'naya gipertenziya. 2009;15(6):697-701. Russian.

Mukhtarova RR. [Early diagnosis of cardio¬vas-cular form of diabetic autonomic neuropathy]. Praktiches¬kaya meditsina. 2013;1(69):75-79. Russian.

Starostin IV, Talitskiy KA, Bulkina OS, Karpov YuA. [Disorders of carbohydrate metabolism and col-lateral blood flow in the myocardium]. Sakharnyy diabet. 2013;58(1):19-26. Russian.

Red'kin YuA. [Diabetic neuropathy: diagnosis, treatment, prevention]. Russkiy meditsinskiy zhurnal. 2015;8:468-471. Russian.

Strokov IA, Fokina AS, Zilov AV. [Aktovegin in the treatment of neurological complications of diabetes]. Effektivna farmakoterapiya. 2015;43:20-27. Russian.

Shavlovskaya OA. [Thioctic acid: antioxidant therapy of neurological diseases] Russian Medical Jour-nal]. Russkiy meditsinskiy zhurnal. 2014;13:960-5. Russian.

Shtemberg LV, Karpov SM, Frantseva AP. [Dete-rmination of autoantibodies to the basic protein world-ling in patients with type 1 diabetes]. Uspekhi sov-remennogo estestvoznaniya. 2014;6:131-2. Russian.

Аyad F, Belhadj M, Paries J, Attali JR, Valensi P. Association between cardiac autonomic neuropathy and hypertension and its potential influence on diabetic com-plications. Diabetiс Medicine. 2010;27:804-11.

Gill G, Woodward A, Casson IF, Weston PJ. Car-diac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes – the «dead in bed» syndrome revisited. Dia-betologia. 2009;52(1):42-45.

Secrest AM, Becker DJ, Kelsey SF, Laporte RE, Orchard TJ. Characterizing sudden death and dead-in-bed syndrome in Type 1 diabetes: analysis from two child¬hood-onset Type 1 diabetes registries. Diabet Med. 2011;28(3):293-300.

Goyal A, Mehta SR, Diaz R. Differential clinical outcomes associated with hypoglycemia and hyper-glycemia in acute myocardial infarction. Circulation. 2009;120:2429-37.

Anaruma CP, Ferreira M, Sponton CG, Delbin MA, Zanesco A. Heart rate variability and plasma bio-markers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise. Diabetes Research and Clinical Practice. 2016;111:19-27.

Christensen TF, Cichosz SL, Tarnow L, Randlov J, Kristensen LE, Struijk JJ, Eldrup E, Hejlesen OK. Hypoglycaemia and QT interval prolongation in type 1 diabetes – bridging the gap between clamp studies and spontaneous episodes. Journal of Diabetes and its Complications. 2014;24(5):723-8.

Lee AS, Brooks BA, Simmons L, Kilborn MJ, Wong J, Twigg SM, Yue DK. Hypoglycaemia and QT interval prolongation: Detection by simultaneous Holter and continuous glucose monitoring. Diabetes research and clinical practice. 2016;113:211-4.

Ishihara M, Kojima S, Sakamoto T. Comparison of blood glucose values on admission for acute myocar-dial infarction in patients with versus without diabetes mellitus. American Journal of Cardiology. 2009;104(6):769-74.

Palatini P, Julius P, Julius S. The role of cardiac auto¬nomic function in hypertension and cardiovascular di¬sease. Currrent Hypertension Reports. 2009;11(3):199-205.

Professional Practice Committee. Standards of Medical Care in Diabetes-2016. Diabetes Care. 2016;39:1-112.

Jaiswal M, Urbina EM, Wadwa RP, Talton JW. Reduced Heart Rate Variability Among Youth With Type 1. Diabetes Diabetes Care. 2013;36:157-62.

Schilling JD, Mann DL. Diabetic cardiomyo¬pa-thy: bench to bedside. Heart Failure Clinics. 2012;8:619-31.

Sheldon E. Diabetes and the Heart: Is There Objective Evidence of a Human Diabetic Cardiomyo-pathy?. Diabetes. 2013;62(10):3329-30.

Tanenberg RJ, Newton CA, Drake AJ. Confir-mation of hypoglycemia in the "dead-in-bed" syndrome, as captured by a retrospective continuous glucose mo-nitoring system. Endocrine Practice. 2010;16(2):244-8.

Hirsch IB, Gard S, Goldstein BJ, Riddle MC. Type 1 Diabetes in Adults – Principles and practice. Jabbour S, Sthephens, EA, editors. NY: Informa healt¬hcare. 2008;288.

Williams S, Chow E, Bernjak A. Risk of cardiac arrhythmias during hypoglycemia in patients with type 2 dia¬betes and cardiovascular risk. Diabetes. 2014;63(5):1738-47.

Ziegler D, Movsesyan L, Mankovsky B. Treat-ment of symptomatic polyneuropathy with actovegin in type 2 diabetic patientsesyan, B. Mankovsky. Diabetes Care. 2009;32(8):1479-84.

Zoungas S. Severe hypoglycemia and risks of vascular events and death. Engl J Med. 2010;363:1410-18.


GOST Style Citations


  1. Аметов А.С. Сахарный диабет 2 типа и сер­дечно-сосудистые заболевания: столкновение двух глобальных неинфекционных эпидемий / А.С. Аме­тов, M.A. Лысенко // Рус. мед. журнал. – 2011. – Т. 19, № 13. – С. 802-804.
  2. Ананьева С.А. Роль альфа-липоевой кислоты в лечении диабетической полинейропатии / С.А. Ана­ньева // Лечащий врач. – 2013. – № 11. – С. 92-94.
  3. Аронов Д.М. Функциональные пробы в кар­диологии / Д.М. Аронов, В.П. Лупанов. – 3-е изд. – Москва: МЕДпресс информ, 2007.– 328 с.
  4. Ахмеджанова Л.Т. Диабетическая полиневро­патия: от многообразия клинических форм к лечению / Л.Т. Ахмеджанова // Эффективная фармакотерапия. Неврология. – 2009. – Т. 23, № 3. – С. 53.
  5. Балаболкин М.И. Дифференциальная диагно­стика и лечение эндокринных заболеваний / М.И. Ба­лаболкин, Е.М. Клебанова, В.М. Креминская. – Москва: МИА, 2008. – 752с.
  6. Валеева Ф.В. Диагностика диабетической ав­тономной кардиальной нейропатии у больных сахар­ным диабетом 1 типа / Ф.В. Валеева, М.Р. Шайдул­лина // Сахарный диабет. –2009 – № 4. – С. 56-59.
  7. Дедов И.И. Алгоритмы специализированной медицинской помощи больным сахарным диабетом. – 7-й вып. / И.И. Дедов, М.В. Шестакова. – Москва, 2015. – 112 с.
  8. Диагностическая значимость бессимптомной депрессии сегмента ST при проведении нагрузочного тестирования у детей и подростков с сахарным диабетом диабетом 1 типа и автономной нейропатией / Д.Н. Лаптев, Т.Л. Кураева, Г.В. Рябыкина, С.Д. По­ляков [и др.] // Сахарный диабет. – 2015. – Т. 18, № 2. – С. 54-60.
  9. Зиновьева О.Е. Препараты альфа-липоевой кис­лоты в лечении диабетической невропатии / О.Е. Зи­новьева // Клинич. медицина. – 2009. –№ 1 – С. 58-62.
  10. Каджарян В.Г. Диабетическая нейропатия: классификация и диагностика / В.Г. Каджарян, А.О. Соловьюк, П.П. Бидзиля // Запорож. мед. жур­нал. – 2010. – Т. 12, № 4. – С. 108-114.
  11. Кравчун Н.А. Вегетативная диабетическая ней­ропатия / Н.А. Кравчун // Здоровье Украины. – 2010. – № 1. – С. 29.
  12. Курникова И.А. Вариабельность артериаль­ного давления в клинико-экспертной диагностике сахарного диабета / И.А. Курникова, Т.Е. Чернышова // Артериальная гипертензия. – 2009. – Т. 15, № 6. – С. 697-701.
  13. Мухтарова Р.P. Ранняя диагностика кардио­васкулярной формы диабетической автономной ней­ропатии / Р.Р. Мухтарова // Практическая медицина. – 2013. – Т. 1, № 69. – С. 75-79.
  14. Нарушения углеводного обмена и колла­теральный кровоток в миокарде / И.В. Старостин, К.А. Талицкий, О.С Булкина, Ю.А. Карпов // Сахар­ный диабет. – 2013. – Т. 58, № 1. – С. 19-26.
  15. Редькин Ю.А. Диабетическая нейропатия: диагностика, лечение, профилактика / Ю.А. Редькин // Рус. мед. журнал. – 2015. – № 8. – С. 468-471.
  16. Строков И.А. Актовегин в лечении неврологи­ческих осложнений сахарного диабета / И.А. Строков, А.С. Фокина, А.В. Зилов // Эффективная фармако­терапия. – 2015. – № 43. – С. 20-27.
  17. Шавловская О.А. Тиоктовая кислота: антиок­сидантная терапия неврологических заболеваний // Рус. мед. журнал. – 2014. – № 13. – С. 960-965.
  18. Штемберг Л.В. Определение аутоантител к ос­новному белку миелина у больных с сахарным диабетом 1 типа / Л.В. Штемберг, С.М. Карпов, А.П. Францева // Успехи соврем. естествознания. – 2014. – № 6. – С. 131-132.
  19. Association between cardiac autonomic neuro­pathy and hypertension and its potential influence on diabetic complications / F. Аyad, M. Belhadj, J. Paries, J.R. Attali, P. Valensi // Diabetiс Medicine. – 2010. – N 27. – P. 804-811.
  20. Cardiac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes – the «dead in bed» syndrome revisited / G. Gill, A. Woodward, I.F. Casson, P.J. Weston // Diabetologia. – 2009. –Vol. 52, N 1. – P. 42-45.
  21. Characterizing sudden death and dead-in-bed syndrome in Type 1 diabetes: analysis from two child­hood-onset Type 1 diabetes registries / D.J. Becker, S.F. Kelsey, R.E. Laporte, T.J. Orchard // Diabet Med. – 2011. – Vol. 28, N 3.–  P. 293-300.
  22. Goyal A. Differential clinical outcomes as­sociated with hypoglycemia and hyperglycemia in acute myocardial infarction /A. Goyal, S.R. Mehta, R. Diaz // Circulation. – 2009. – Vol. 120. – P. 2429-2437.
  23. Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise / C.P. Anaruma, M. Ferreira, C.G. Spon­ton, M.A. Delbin [et al.] // Diabetes Research Cli­nical Practice – 2016. – Vo1. 111. –P. 19-27.
  24. Hypoglycaemia and QT interval prolongation in type 1 diabetes – bridging the gap between clamp studies and spontaneous episodes / T.F. Christensen, S.L. Ci­chosz, L. Tarnow, J. Randlov [et al.] // J. Diabetes and its Complications. – 2014. – Vol. 24, N5. – P. 723-728.
  25. Hypoglycaemia and QT interval prolongation: Detection by simultaneous Holter and continuous glucose monitoring / A.S. Lee,B.A.Brooks, L. Simmons, M.J. Kilborn [et al.] // Diabetes research and  clinical practice. – 2016. – Vol. 113. – P. 211-214.
  26. Ishihara M. Comparison of blood glucose values on admission for acute myocardial infarction in patients with versus without diabetes mellitus / M. Ishihara, S. Kojima, T. Sakamoto // Am. J. Cardiology. – 2009. – Vol. 104, N 6. – P. 769-774.
  27. Palatini P. The role of cardiac autonomic function in hypertension and cardiovascular disease / P. Palatini, P. Julius, S. Julius // Currrent Hypertension Reports. – 2009. – Vol. 11, N 3. – P. 199-205.
  28. Professional Practice Committee / Standards of Medical Care in Diabetes-2016 // Diabetes Care. – 2016. – Vol. 39. – P. 1-112.
  29. Reduced Heart Rate Variability Among Youth With Type 1 / M. Jaiswal, E.M. Urbina, R.P. Wadwa, J.W. Talton // Diabetes Care – 2013. – N 36. – P. 157-162.
  30. Schilling J.D. Diabetic cardiomyopathy: bench to bedside / J.D. Schilling, D.L. Mann // Heart Failure Cli­nics. ─ 2012. – N 8. – P. 619-631.
  31. Sheldon E. Diabetes and the Heart: Is There Objective Evidence of a Human Diabetic Cardiomyo­pathy? / E. Sheldon // Diabetes. – 2013. – Vol. 62, N 10. – P. 3329-3330.
  32. Tanenberg R.J. Confirmation of hypoglycemia in the "dead-in-bed" syndrome, as captured by a retro­spective continuous glucose monitoring system / R.J. Ta­nenberg, С.A Newton, A.J Drake // Endocrine Practice. — 2010. — Vol 16, N 2. — P. 244-248.
  33. Type 1 Diabetes in Adults – Principles and practice / I.B. Hirsch,S. Gard, B.J. Goldstein, M.C. Riddle [et al.] -NY: Informa healthcare, 2008. – 288 p.
  34. Williams S. Risk of cardiac arrhythmias during hypoglycemia in patients with type 2 diabetes and cardio­vascular risk / E. Chow, A. Bernjak, S. Williams // Dia­betes. – 2014. – Vol. 63, N 5. – P. 1738-1747.
  35. Ziegler D. Treatment of symptomatic polyneuro­pathy with actovegin in type 2 diabetic patients / D. Ziegler, L. Movsesyan, B. Mankovsky / Diabetes Care. – 2009. – Vol. 32, N 8. – P.1479-1484.
  36. Zoungas S. Severe hypoglycemia and risks of vascular events and death /S. Zoungas, A. Patel, J. Chal­mers // N. Engl. J. Med. – 2010. – Vol. 363. – P. 1410-1418.




 

This work is licensed under a Creative Commons Attribution 4.0 International License