Clinical characteristics of cephalalgia at patients with arterial hypertension during intermittent fasting.

Authors

DOI:

https://doi.org/10.26641/2307-0404.2019.2.170151

Keywords:

intermittent fasting, therapeutical fasting, interval feeding, arterial hypertension, headache, cephalalgia

Abstract

The study of the effectiveness and safety of intermittent fasting (IF) at 185 patients aged from 25 to 75 years (mean age – 48,6 years) with arterial hypertension (AH) and headache was carried out. AH was seen as the most likely factor of cerebral discirculation and associated cephalgia. Patients volunteered to maintain a short-term dietary restriction with terms of 16 or 24 hours once in 7 days over a period of 4 weeks. During this period, 43 patients stopped participation in the study, of which 31 - at 24-hour IF and 12 - at 16-hour IF. The assessment of the influence on cephalgia was considered positive when the score of visual analog scale (VAS) was decreased by 2 or more points and / or there was a significant decrease in the duration and frequency of cephalgia attacks. In a rhythmic diet with a 16-hour food intake missing, a positive result was registered at 35% (37,25% of young patients, 40,48% – of  average and 28,57% of the elderly) without a significant difference between ages. The effectiveness of a 24-hour type of IF was higher and made up about 75% in all age groups. Negative side effects of IF that would require its termination due to objective reasons (threatening changes in blood pressure, syncope states and others) were not recorded, the most common complaints were the feeling of hunger (from 50 to 76% with a difference in age), psychological tension, uncertain anxiety (on average about 32%). The authors consider that such a psychological feature - namely, the impossibility and unwillingness to endure short-term fasting was a main factor of refusal to continue the treatment regimen, and within certain limits prevents the wider use of IF method in the treatment of cephalgia. In general, the efficacy of a 24-hour IF compared with a 16-hour type was significantly higher, without severe side effects.

Author Biographies

Liu Chun

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of neurology and ophthalmology
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

O. V. Pohorielov

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of neurology and ophthalmology
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

References

Fann DY, Ng GY, Poh L, Arumugam TV. Positive effects of intermittent fasting in ischemic stroke (Review). Exp Gerontol. 2017;89(93):102. doi: https://doi.org/10.1016/j.exger.2017.01.014

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1-211. doi: https://doi.org/10.1177/0333102417738202

Mattson MP, Longo VD, Harvie M. Impact of intermittent fasting on health and disease processes. Ageing Res. 2017;39:46-58. doi: https://doi.org/10.1016/j.arr.2016.10.005

Michalsen A, Li C. Fasting therapy for treating and preventing disease - current state of evidence. Karger GmbH, Freiburg. Forsch Komplementmed. 2013;20(6):434-43. doi: https://doi.org/10.1159/000357602

Obert J, Pearlman M, Obert L, Chapin S. Popular Weight Loss Strategies: a Review of Four Weight Loss Techniques. Curr Gastroenterol Rep. 2017;19(12):61. DOI: https://doi.org/10.1007/s11894-017-0603-8

Saracco MG, et al. Relationship between primary headache and nutrition: a questionnaire about dietary habits of patients with headache. Neurol Sci. 2014;35(1):159-61. doi: https://doi.org/10.1007/s10072-014-1760-2

Stockman MC, Thomas D, Burke J, Apovian C. Intermittent Fasting: Is the Wait Worth the Weight? Curr Obes Rep. 2018;7(2):172-85. doi: https://doi.org/10.1007/s13679-018-0308-9

Tinsley GM, Horne BD. Intermittent fasting and cardiovascular disease: current evidence and unresolved questions (Review). Future Cardiol. 2018;14(1):47-54. doi: https://doi.org/10.2217/fca-2017-0038

Whelton PK. 2017 ACC/AHA/AAPA/ABC/ ACPM/ AGS/ APhA/ ASH/ ASPC/ NMA/ PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension.2018;71:1269–1324. doi: https://doi.org/10.1161/HYP.0000000000000066

Zaeem Z, Zhou, Dilli E. Headaches: a Review of the Role of Dietary Factors. Current Neurology and Neuroscience Reports. 2016:16(11):101. doi: https://doi.org/10.1007/s11910-016-0702-1

How to Cite

1.
Chun L, Pohorielov OV. Clinical characteristics of cephalalgia at patients with arterial hypertension during intermittent fasting. Med. perspekt. [Internet]. 2019Jun.18 [cited 2024Mar.28];24(2):59-65. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/170151

Issue

Section

CLINICAL MEDICINE