Complex treatment of generalized catarrhal gingivitis with precursors of early formation of destructive phenomena in the bone structures of periodontium.
Keywords:generalized catarrhal gingivitis, generalized periodontitis, microbiocenosis, immunodeficiency
The article presents the results of comprehensive rehabilitation of 92 patients with generalized catarrhal gingivitis by creating differentiated programs for prevention and treatment of the disease, depending on the absence or presence of laboratory signs that have not been detected by X-ray, early destructive processes in the bone structures of periodontal tissues. It was revealed that appearance in gums tissue of representatives of the major periodontal bacteria is a precursor to the development of initial stage of generalized periodontitis in it. It was established that the earlier objective indicators of bone resorptive process in periodontal tissues in patients with generalized catarrhal gingivitis is an overproduction of proinflammatory cytokines IL-1.beta and TNF-alpha and the lack of anti-inflammatory cytokineIL-4.
Belousov NN. [Causes of widespread severe inflammatory periodontal diseases]. Periodontology. 2005;36(3):26-29. Russian.
Mashchenko IS. [Periodontal diseases].Dnepropetrovsk:Colo.2003;271. Russian.
Сepov L, Nikolaev A, Mikheeva E. [Diagnosis, treatment and prevention of periodontal disease]. MEDpress. 2008;272. Russian.
Cochran DL. Inflammation and bone loss in periodontal disease. J Periodontol 2008;79:1569-1576.
Rescala B, Rosalem W, Teles RP, Fischer RG, Haffajee AD, Socransky SS, Gustafsson A, Figueredo CM. Immunological and microbiologic profiles of chronic and aggressive periodontitis subjects. J. Periodontol. 2010;81:1308-16.
Manchini G, Garbonara AO, Heremans SF. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965;2(6):234-5.
Michael PM. Immunological and Inflammatory Aspects of Periodontal Disease. Continuing Education Course. 2013;1-18.
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