Diagnosis and prognosis of COPD exacerbations in overweight patients.


  • N. V. Korzh




chronic obstructive pulmonary disease, overweight, IL-6, C-reactive protein


Increasing incidence of chronic obstructive pulmonary disease (4th place among all causes of death within the general population) and overweight, as one factor for progression of respiratory tract pathologies (more than 30% of world population suffers from overweight) suggests that further study of pathogenetic characteristics of their combined course and search for new ways of differential pathogenetic therapy are important nowadays. The aim if the investigation is the diagnosis and prognosis of COPD exacerbations in overweight patients. The results of this investigation demonstrate, that overweight is the predictor of COPD progression, that is accompanied by elevations of CRP and IL-6 levels in peripheral blood serum.

Author Biography

N. V. Korzh

SHEI «Ivano-Frankivsk National Medical University»
Department of tuberculosis and pulmonology with a course of occupational disease
Halytcka str., 2, Ivano-Frankivsk, 76000, Ukraine


Bychkova SA,BychkovaNH. [Clinical and func­tional features of the course of chronic obstructive pul­monary disease combined with metabolic syndrome]. Likarska sprava. 2014;7-8:54-9. Ukrainian.

Havrysiuk VK. [Systemic manifestations of COPD: clinical features, diagnosis and treatment].Ukr Pulm J. 2009;2:7. Russian.

Hashynova EY. [Systemic effects and comor­bi­di­ty in outpatients with COPD]. Ukr Pulm J. 2013; 2:41-5. Russian.

HashynovaKY.[Influence of comorbid patho­logy on the frequency of hospitalizations when exacer­bated by chronic obstructive pulmonary disease]. Hal lik visnyk. 2014;21(3):15–8. Ukrainian.

IlnytskyiRI. [Features of immunological reac­tivity in patients with chronic obstructive pulmonary disease]. Ukr Pulm J. 2007; 2:21-4. Ukrainian.

Konopkina LI. [Level of markers of systemic inflammation in patients with chronic obstructive pul­monary disease of severe course depending on their adherence to planned therapy]. Problems of ecology and medicine. 2012:16(5-6):15-8. Ukrainian.

Mostovyi YM. [Chronic obstructive pulmonary disease. Key issues]. Ukr Med J. 2016;4:63-6. Ukrainian.

Ostrovsky MM, Herych PR. [On the issue of polymorbidity and comorbidity in patients with COPD]. Ukr Pulm J. 2011;4:19-24. Ukrainian.

Pertseva TO, Sanina NA. [The role of systemic inflammatory processes in the pathogenesis of chronic ob­structive pulmonary disease]. Ukr Pulm J. 2012;4:48-50. Ukrainian.

[On approval and implementation of medical-technological documents on standardization of medical care in chronic obstructive pulmonary disease: Order of the Ministry of Health ofUkraine№555 from June 27, 2013]. Ministry of Health ofUkraine. Official issue. Kyiv; 2007. Ukrainian.

Dihtiar NI,HerasymenkoND, Savchenko LV, et al. [Systemic inflammation of low intensity as the general basis of chronic obstructive pulmonary disease and co­morbid conditions]. Ukr Pulm J. 2016;3:64-8. Ukrainian.

Yashyna LA, Ishchuk SH. [Excessive body weight, obesity and pathology of the lungs: a view of the pulmonologist]. Zdorovia Ukrainy. 2011;2(4):14. Russian.

Agusti AG. Systemic effects of chronic obstruc­tive pulmonary disease. Proc Am Thorac Soc. 2005;2:367-70.

Vanfleteren LE,et al. Body mass index and chro­nic airflow limitation in a worldwide population-based study]. Chron Respir Dis. 2016;13(2):90-101.

Global Initiative for Chronic Obstructive Lung Diseases (GOLD). Global strategy for diagnosis, mana­gement, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO workshop report. Updated 2017.

How to Cite

Korzh NV. Diagnosis and prognosis of COPD exacerbations in overweight patients. Med. perspekt. [Internet]. 2018Apr.24 [cited 2024Jun.24];23(1(part1):82-6. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/127242