Phenotypic symptoms of conjugate tissue dysplasia in persons of young age with mitral valve prolapse.

Authors

  • M. A. Kuznetsova

DOI:

https://doi.org/10.26641/2307-0404.2018.2(part1).129509

Keywords:

mitral valve prolapse, connective tissue dysplasia, phenotypic signs, young age

Abstract

In connection with the significant increase in complications, developing in young people with mitral valve prolapse (MVP), the study of phenotypic signs and peculiarities of the formation of this pathology is topical. A survey of 135 young people aged 17-25 years with mitral valve prolapse was conducted. The patients were examined by specialist-doctors: neuropathologist, otorhinolaryngologist, surgeon, traumatologist and oculist to exclude organic pathology; the distribution of phenotypic signs of connective tissue dysplasia depending on degree of MVP was evaluated. It was established that in young people with MVP of 2nd degree external and visceral manifestations of connective tissue dysplasia occur significantly more often than in persons with MVP of 1 degree.

References

Bart BYa, Benevskaya VF. [Prolapse of the mitral valve in practice of physician and cardiologist]. Te­rapevticheskiy arkhiv. 2003; 1:10-15. Russian.

Gromova OA. [Possible molecular mechanisms of the effect of magnesium deficiency and orotic acid on dys­plasia of connective tissue]. Esteticheskaya meditsina. 2008;7(4):3-11. Russian.

Demin VF, Klyuchnikov SO, Klyuchnikova MA. [The value of the connective tissue dysplasia in pathology in children]. Voprosy sovremennoy pediatrii. 2005;1:50-6. Russian.

Klemenov AV. [Extracardiac manifestations of con­nective tissue dysplasia with mitral valve prolapse]. Ros. kardiol. zhurn. 2004;1:87-9. Russian.

Klemenov AV. [Primary mitral valve prolapse]. Izd. 3-e, pererab. i dop. 2006;10-21. Russian.

Moiseev S. [Mitral valve prolapse: Current As­pects]. Vrach. 2005;11:19-22. Russian.

[Hereditary disorders structure and function of connective tissue]. Moskva, Rosiyskie rekomendatsii; 2009. Russian.

Nechaeva G, Viktorova I,DrukI.[Connective tis­sue dysplasia: prevalence, phenotypic characteristics, as­sociation with other diseases]. Vrach. 2006;1:19-23. Russian.

Ostropolets SS. [Connective tissue dysplasia - a disease or a third state?]. Theses of the VIII All-Ukrainian Scientific and Practical Conference" Actual Issues of Pediatrics". Conference. Kyiv. 2006;66. Ukrainian.

Makolkin VI, Podzolyakov VI, Radionov AV, et al. [Polymorphism of clinical manifestations of con­nective tissue dysplasia]. Terapevticheskiy arkhiv. 2004;11:77-80. Russian.

Dyadyk AI, Bagriy AE, Grishin DV, Samoylova OV, Tyurkyan KR. [Mitral valve prolapse: modern ideas about the item, epidemiology, diagnosis, prognosis and tactics]. Ukraїns'kiy terapevtichniy zhurnal. 2004;3:98-103. Russian.

Filipenko PS. [The role of connective tissue dys­plasia in the formation of mitral valve prolapsed]. Klin. meditsina. 2006;12:13-9. Russian.

ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of theAmericanCollegeof Cardiology. American Heart As­sociation Task Force on Practice Guidelines. J. Amer. Coll. Cardiol. 2006;48(3):148.

Anders S, Said F. Mitral valve prolapsed synd­rome as cause of sudden death in young adults. Forensic Sci Int. 2007;171(2-3):127-130.

Downloads

How to Cite

1.
Kuznetsova MA. Phenotypic symptoms of conjugate tissue dysplasia in persons of young age with mitral valve prolapse. Med. perspekt. [Internet]. 2018May24 [cited 2024Nov.25];23(2(part1):15-8. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/129509

Issue

Vol. 23 No. 2(part1) (2018)

Section

CLINICAL MEDICINE

License

Copyright (c) 2018 Medicni perspektivi (Medical perspectives)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.

Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.