Modern tactics of managing patients with pulmonary arterial hypertension associated with systemic connective tissue diseases.


  • O. O. Khaniukov
  • L. I. Vasylieva
  • Ye. D. Yehudina
  • O. S. Kalashnykova



pulmonary arterial hypertension, systemic connective tissue diseases, systemic scleroderma


A review of the literature on the problem of one of the rare manifestations of systemic diseases - pulmonary arterial hypertension is presented. The necessity of early and thorough differential diagnosis, verification of the diagnosis using invasive methods for assessing central hemodynamics is substantiated. A model for screening patients with systemic scle­roderma, which simplifies the determination of indications to set the research methods that allow to verify the diagnosis is proposed. Modern approaches to drug therapy are described, and questions of improving the patients’ survival with this prognostically unfavorable pathology are discussed.

Author Biographies

O. O. Khaniukov

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of internal medicine 3
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

L. I. Vasylieva

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of internal medicine 3
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

Ye. D. Yehudina

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of internal medicine 3
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

O. S. Kalashnykova

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of internal medicine 3
V. Vernadsky str., 9, Dnipro, 49044, Ukraine


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How to Cite

Khaniukov OO, Vasylieva LI, Yehudina YD, Kalashnykova OS. Modern tactics of managing patients with pulmonary arterial hypertension associated with systemic connective tissue diseases. Med. perspekt. [Internet]. 2018Jun.25 [cited 2023Dec.5];23(2):35-46. Available from: