Parenchymal-stem segmental portal vein embolization as a stage of preparation of patients with malignant liver tumors to surgical treatment
DOI:
https://doi.org/10.26641/2307-0404.2018.2.133940Keywords:
portal portal embolization, hepatic resectionAbstract
Article presents results of the study of the parenchymal-stem segmental portal vein embolization (PVE) efficacy, performed in patients with advanced malignant liver tumors and a marginally small hepatic residue as preoperative preparation. The technical efficiency of PVE was studied by comparing 218 patients who underwent parenchymal-stem segmental modification of PVE (main group) and 124 patients who underwent other PVE modifications (comparison group). It was noted that in the main group PVE was followed with 6.1% lower percentage of complications (6.0% versus 12.1%), which allowed to perform a successful technical EEV in 205 (94.0% main and 124 (83.9%) the comparison group. Radical liver resection was performed in 286 (83.6%) of the total amount of patients, 192 (88.1%) – in the main group, and 94 (75.8%) – in the comparison group. Thus, the introduction of parenchymal-stem segmental embolization of the portal vein allowed to expand the range of operability of patients with advanced malignant liver tumors by 12.3% (from 75.8% to 88.1%).
References
Abdalla EK, Barnett CC, Doherty D, Curley SA, Vauthey JN. Extended hepatectomy in patients with hepatobiliary malignancies with and without preoperative portal vein embolization. Arch Surg. 2002 Jun;137(6):675-80. doi: 10.1001/archsurg.137.6.675
Wakabayashi H, Ishimura K, Okano K, Izuishi K, Karasawa Y, Goda F, et al. Is preoperative portal vein embolization effective in improving prognosis after major hepatic resection in patients with advanced-stage hepatocellular carcinoma? Cancer. 2001 Nov 1;92(9):2384-90. doi: 10.1002/1097-0142(20011101)92:9<2384:AID-CNCR1586>3.0.CO;2-H
Fischman AM, Ward TJ, Horn JC, Kim E, et al. Portal vein embolization before right hepatectomy or extended right hepatectomy using sodium tetradecyl sulfate foam: technique and initial results. J Vasc Interv Radiol. 2014 Jul;25(7):1045-53. doi: 10.1016/j.jvir.2014.01.034
Makuuchi M, Thai BL, Takayasu K, Takayama T, Kosuge T, Gunvén P, et al. Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma: a preliminary report. Surgery. 1990 May;107(5):521-7. PMID: 2333592.
Ko GY, Sung KB, Yoon HK, Kim JH, Weon YC, Song HY. Preoperative Portal Vein Embolization with a New Liquid Embolic Agent. Radiology. 2003;227(2):407-13. doi: 10.1148/radiol.2272011702/
Sofue K, Arai Y, Shimada K, Takeuchi Y, Kobayashi T, Satake M, et al. Right portal vein embolization with absolute ethanol in major hepatic resection for hepatobiliary malignancy. Br J Surg. 2014 Aug;101(9):1122-8. doi: 10.1002/bjs.9541
Nagino M, Kamiya J, Nishio H, Ebata T, Arai T, Nimura Y. Two hundred forty consecutive portal vein embolizations before extended hepatectomy for biliary cancer: surgical outcome and long-term follow-up. Ann Surg. 2006 Mar;243(3):364-72. doi: 10.1097/01.sla.0000201482.11876.14
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