Optimization of treatment of patients with arterial hypertension in combination with coronary heart disease.

Authors

  • S. О. Sheiko
  • N. О. Kolb

DOI:

https://doi.org/10.26641/2307-0404.2018.2.133948

Keywords:

arterial hypertension, ischemic heart disease, combined therapy

Abstract

Arterial hypertension (AH) is one of the most important risk factors for atherosclerosis, mainly coronary heart disease (CHD) and damage to the brain vessels. Especially often there is a combination of CHD and hypertension. There is a great need in systematizing the approaches to antihypertensive therapy in patients with coronary artery disease, as well as treating coronary artery disease in patients with hypertension. The aim of this work was to study the clinical efficacy and adherence to treatment of patients with hypertension in combination with CHD with a fixed combination of β-adrenoblockators bisoprolola fumarate (5 mg) and calcium channel blockers - amlodipine (5 mg) (alothedine). The use of alotdine in patients with hypertension and coronary artery disease with a high cardiovascular risk provides a significant anti-ischemic effect in combination with a clear antihypertensive effect. Normalization of daily blood pressure monitoring in patients at high risk shows a significant positive result which affects the long-term prognosis of the disease and the development of complications. The fixed combination of bisoprolol and amlodipine provides a high degree of patients’ adherence to treatment.

Author Biographies

S. О. Sheiko

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Pediatrics, Family Medicine and Clinical Laboratory Diagnostics
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

N. О. Kolb

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Pediatrics, Family Medicine and Clinical Laboratory Diagnostics
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

References

Davydova IV, Korost YaV. [Combination therapy in the modern treatment of arterial hypertension: fixed and non-fixed combinations]. Lіky Ukrainy. 2017;2(208):24-29. Ukrainian.

Kuryata OV, Sirenko OYu. [Daily blood pressure profile, lipid blood spectrum in patients with arterial hypertension in combination with rheumatoid arthritis and the efficacy of atorvastatin]. Sіmeina medytsyna 2015;3(59):155-9. Ukrainian.

Маkаrоv LМ. [Holter моnitoring]. Мoskva, Med. praktika. 2008;456. Russian.

[The guidance and clinical protocol for the pro­vision of medical aid "Arterial hypertension": Order of the Ministry of Health N 384. Effective from 24.05.2012.]. Kyiv, 2012;108. Ukrainian.

Rebrova OYu. [Statistical analysis of medical data. Application software package STATISTICA]. Moskva. 2002;312. Russian.

Tseluyko VI, Avilova YaM, Alchinskiy IV, Anti­penko ID, et al. [The realities of the treatment of arterial hypertension inUkraine: the results of the cohort study SYSTEMA-2]. Ukr. kardіol. zhurnal. 2018;1. Russian.

Kotseva K, Wood D, De Bacquer D, De Ba­cker G, et al. EUROASPIRE IV: A European Society of Cardiology survey on the lifestyle, risk factor and the­rapeutic management of coronary patients from 24 European countries. EUROASPIRE Investigators. Eur J. Prev. Cardiol. 2016;23(6):636-48.

Fox K, Garcia MA, Ardissino D, et al. Guidelines on the management of stable angina pectoris: executive summary: the Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. Eur. Heart J. 2006;27:1341-81.

Erhardt L, Herlitz J, Bossaert L. Task force on the management of chest pain. Eur. Heart J. 2002;23:1153-76.

The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension and of the European Society of Cardiology. 2007 Guidelines for the management of arterial hypertension. Eur. Heart J. 2007;28:1462-536.

Rosendorff C, Black HR, Cannon CP, et al. Treatment of Hypertension in the Prevention and Management of Ischemic Heart Disease: A Scientific Statement From the American Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and Prevention. Circulation. 2007;115:2761-88.

How to Cite

1.
Sheiko SО, Kolb NО. Optimization of treatment of patients with arterial hypertension in combination with coronary heart disease. Med. perspekt. [Internet]. 2018Jun.25 [cited 2024Dec.10];23(2):119-25. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/133948

Issue

Section

CLINICAL MEDICINE