Optimization of treatment of patients with arterial hypertension in combination with coronary heart disease.
Keywords:arterial hypertension, ischemic heart disease, combined therapy
Arterial hypertension (AH) is one of the most important risk factors for atherosclerosis, mainly coronary heart disease (CHD) and damage to the brain vessels. Especially often there is a combination of CHD and hypertension. There is a great need in systematizing the approaches to antihypertensive therapy in patients with coronary artery disease, as well as treating coronary artery disease in patients with hypertension. The aim of this work was to study the clinical efficacy and adherence to treatment of patients with hypertension in combination with CHD with a fixed combination of β-adrenoblockators bisoprolola fumarate (5 mg) and calcium channel blockers - amlodipine (5 mg) (alothedine). The use of alotdine in patients with hypertension and coronary artery disease with a high cardiovascular risk provides a significant anti-ischemic effect in combination with a clear antihypertensive effect. Normalization of daily blood pressure monitoring in patients at high risk shows a significant positive result which affects the long-term prognosis of the disease and the development of complications. The fixed combination of bisoprolol and amlodipine provides a high degree of patients’ adherence to treatment.
Davydova IV, Korost YaV. [Combination therapy in the modern treatment of arterial hypertension: fixed and non-fixed combinations]. Lіky Ukrainy. 2017;2(208):24-29. Ukrainian.
Kuryata OV, Sirenko OYu. [Daily blood pressure profile, lipid blood spectrum in patients with arterial hypertension in combination with rheumatoid arthritis and the efficacy of atorvastatin]. Sіmeina medytsyna 2015;3(59):155-9. Ukrainian.
Маkаrоv LМ. [Holter моnitoring]. Мoskva, Med. praktika. 2008;456. Russian.
[The guidance and clinical protocol for the provision of medical aid "Arterial hypertension": Order of the Ministry of Health N 384. Effective from 24.05.2012.]. Kyiv, 2012;108. Ukrainian.
Rebrova OYu. [Statistical analysis of medical data. Application software package STATISTICA]. Moskva. 2002;312. Russian.
Tseluyko VI, Avilova YaM, Alchinskiy IV, Antipenko ID, et al. [The realities of the treatment of arterial hypertension inUkraine: the results of the cohort study SYSTEMA-2]. Ukr. kardіol. zhurnal. 2018;1. Russian.
Kotseva K, Wood D, De Bacquer D, De Backer G, et al. EUROASPIRE IV: A European Society of Cardiology survey on the lifestyle, risk factor and therapeutic management of coronary patients from 24 European countries. EUROASPIRE Investigators. Eur J. Prev. Cardiol. 2016;23(6):636-48.
Fox K, Garcia MA, Ardissino D, et al. Guidelines on the management of stable angina pectoris: executive summary: the Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. Eur. Heart J. 2006;27:1341-81.
Erhardt L, Herlitz J, Bossaert L. Task force on the management of chest pain. Eur. Heart J. 2002;23:1153-76.
The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension and of the European Society of Cardiology. 2007 Guidelines for the management of arterial hypertension. Eur. Heart J. 2007;28:1462-536.
Rosendorff C, Black HR, Cannon CP, et al. Treatment of Hypertension in the Prevention and Management of Ischemic Heart Disease: A Scientific Statement From the American Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and Prevention. Circulation. 2007;115:2761-88.
How to Cite
Copyright (c) 2018 Medicni perspektivi (Medical perspectives)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.
Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.