The state of oral mucosa in patients with type 2 diabetes

Authors

DOI:

https://doi.org/10.26641/2307-0404.2020.3.214854

Keywords:

diabetes mellitus, oral mucosa, generalized periodontitis, tooth decay

Abstract

Aspects of the relationship between somatic and dental diseases are multifaceted. The bi-directional, mutually aggravating nature of the relationship between somatic and dental pathology is exemplified by diabetes mellitus. Numerous studies indicate that uncontrolled diabetes contributes to a multiple increase in the risk of caries and tooth loss, damage to the salivary glands, periodontium and oral mucosa. Given that diabetes affects all the main components of the etiology and pathogenesis of dental diseases, the urgent task of dentistry is to develop adequate methods for the treatment and prevention of dental pathology due to the presence of diabetes in the patient, which cannot be done without assessing the dental status of patients in this category. The purpose of the study was a comparative assessment of the state of oral tissues in patients with type 2 diabetes and in people of the similar age without somatic pathology. We examined 70 patients aged 34-48 years, of which 35 patients with type 2 diabetes and 35 healthy individuals of the similar age. Recruitment of patients with diabetes was carried out on the basis of the Communal non-profit enterprise "Odessa Regional Endocrinological Dispensary." All patients were clinically and radiologically examined. It was shown that the prevalence and intensity of the carious process in people with diabetes did not differ from the control group, however, the “M” component prevailed in the structure of the DMF index, the need for prosthetics was 79.1%. Hygiene was by 21.8% worse. All patients with diabetes were diagnosed with generalized periodontitis with the prevalence of an exacerbated course (25.7% more) and a direct dependence of the severity of periodontitis from the degree of decompensation of diabetes. Periodontal indices in patients with diabetes were increased: PMA index – by 70.6%, bleeding index – by 2 times, Russell index – by 1.9 times. In 63.6% of patients with diabetes, changes in the oral mucosa were noted. 25.7% of patients noted the development of candidal stomatitis / glossitis in the past. The functional activity of the salivary glands was reduced by 38.1%. Micro­crystallization of saliva in patients with diabetes is represented mainly by IV and V classes according to Leus-Kukina, which indicates its reduced mineralizing ability and the maximum risk of tooth decay.

Author Biographies

S. A. Shnaider

SE "The Institute of Stomatology and Maxillo-Facial Surgery National Academy of Medical Sciences of Ukraine" 
Rishelievska st., 11, Odessa, 65026, Ukraine

V. Ya. Skyba

SE "The Institute of Stomatology and Maxillo-Facial Surgery National Academy of Medical Sciences of Ukraine" 
Rishelievska st., 11, Odessa, 65026, Ukraine

O. V. Skyba

SE "The Institute of Stomatology and Maxillo-Facial Surgery National Academy of Medical Sciences of Ukraine" 
Rishelievska st., 11, Odessa, 65026, Ukraine

H. O. Babenya

SE "The Institute of Stomatology and Maxillo-Facial Surgery National Academy of Medical Sciences of Ukraine" 
Rishelievska st., 11, Odessa, 65026, Ukraine

S. D. Varzhapetian

SE “Zaporizhzhia Medical Academy of Postgraduate Education of Ministry of Health of Ukraine” 
Vintera boul. 20, Zaporizhzhia, 69096, Ukraine

References

Volkova EA, Malygina OF. [Diabetes mellitus and cardiovascular diseases. Actual approach to lifestyle modification and treatment of patients with type 2 diabetes]. Consilium Medicum. 2019;21(1):74-80. Russian. doi: https://doi.org/10.26442/20751753.2019.1.190273

Leontev VK, Kiselnikova LP. [Pediatric Thera­peutic Dentistry: National Guide]. Moskva: GEOTAR-Media; 2017. p. 952. Russian.

Zubov NN, Kuvakin VI, editors. [Methods of multivariate statistical data analysis in medicine: a trai­ning manual]. Sankt-Peterburg: OOO "Litografiya Print"; 2017. p. 348. Russian.

Klenovska SV. [Comparative aspects of candi­diasis in patients with diabetes mellitus]. East European Science Journal. 2018;9(37 part 2):22-26. Ukrainian.

Leus PA. [Dental health indicators. What they point to?]. Sovremennaya stomatologiya. 2015;1:4-7. Russian.

Naumova VN, Turkina SV, Maslak EE. [The rela­tionship of dental and somatic diseases]. Volgogradskiy nauchno-medicinskiy zhurnal. 2016;2:25-28. Russian.

Nemtsova VD. [Diabetes mellitus and sudden death: resolved and unresolved issues]. Svit medytsyny ta biologii. 2015;2(50):206-211. Russian.

Danylevskyi NF, et al. [Therapeutic dentistry: in 4 volumes – Vol. 3. Periodontal disease: a textbook]. Borysenko AV, editor. Kyiv: Medytsyna; 2018. p. 624. Ukrainian.

Tsytovskyi MN. [Statistical, clinical and morpho­logical aspects of the flow of cerebral diabetes to the camp of the heart-ship system]. Naukovyi visnyk Uzhgo­rodskogo universytetu: Medycyna. 2017:1(55):168-77. Ukrainian.

[Resolution of the round table meeting of the Health Committee of the Verkhovna Rada of Ukraine “Diabetes. International experience. Problems and oppor­tu­nities in Ukraine"]. Kyiv; (2018). Ukrainian. Available from: http://komzdrav.rada.gov.ua/uploads/documents/30887.pdf

American Diabetes Association. Diabetes Care. 2015;38(1):1-594.

Global report on diabetes, WHO, 2018:84. Available from: https://apps.who.int/iris/bitstream/handle/10665/204871/9789241565257_eng.pdf?sequence=1

Kilmukhametova YuH, Batig VM, Basista AS. Periodontal diseases on the background of various so­matic pathologies. Deutscher Wissenschaftsherold. 2018;3:26-29. doi: https://doi.org/10.19221/201838

Mehmet E Okur, Ioannis D Karantas, Panoraia I Siafaka. Diabetes Mellitus: A Review on Patho­physiology, Current Status of Oral Medications and Future Perspectives. Acta Pharm. Sci. 2017;55(1). doi: https://doi.org/10.23893/1307-2080.APS.0555

Sadeghi R, Taleghani F, Mohammadi S, Zohri Z. The effect of diabetes mellitus type i on periodontal and dental status. J Clin Diagn Res. 2017 Jul;11(7):ZC14-7. doi: https://doi.org/10.7860/JCDR/2017/25742.10153

Published

2020-10-05

How to Cite

1.
Shnaider SA, Skyba VY, Skyba OV, Babenya HO, Varzhapetian SD. The state of oral mucosa in patients with type 2 diabetes. Med. perspekt. [Internet]. 2020Oct.5 [cited 2024Jun.19];25(3):153-60. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/214854

Issue

Section

CLINICAL MEDICINE