Possibilities of rehabilitation treatment of children with lymphoblastic leukemia (literary review)

Authors

DOI:

https://doi.org/10.26641/2307-0404.2021.4.248084

Keywords:

children, lymphoblastic leukemia, rehabilitation

Abstract

According to nowaday protocols of acute lymphoblastic leukemia (ALL) treatment, the percentage of recovering patients has increased significantly. This determines the necessity for comlex long-term rehabilitation, as chemotherapeutic drugs are highly toxic and contribute to the development of comorbid diseases of the gastrointestinal tract, nervous and musculosceletal systems. The purpose of the study was to review and analyze data from foreign and domestic literature concerning possibilities for rehabilitative treatment of children with ALL and to reveal informative methods assessing the effectiveness of rehabilitation. Important elements of rehabilitation goals and assessment of its the effectiveness are the International Classification of Functioning, Disability and Health of Children and Adolescents, and the Quality of Childrens’ Life. Rehabilitation begins at the hospital and includes psychological support for the child with the involvement of psychotherapists and family, as well as the performance of certain physical exercises lasting for 15-30 minutes, which are selected individually, taking into account the functional capabilities and motivation of the child. After the acute period, physical activity is carried out in accordance with an individual plan, which takes into account the peculiarities of the disease and includes active video games, cycling and other activities. Rehabilitation treatment on the basis of sanatorium-resort institutions with the participation of a multidisciplinary team is actual. Such treatment, in addition to physical exercises, includes the use of natural and preformed physical factors in order to influence the manifestations of comorbid pathology, and also contributes to an increase of the social activity and independence of the child. However, the number of such studies is limited, which determines the necessity to develop clear practical recommendations regarding methods of exposure, their duration and intensity.

References

Grushina TI. [Physiotherapy in the Medical Rehabilitation of Children with Malignant Tumors (Scien¬tific Review)]. Onkopediatriya. 2018;5(3):164–174. Russian. doi: https://doi.org/10.15690/onco.v5i3.1934

Kaladze NN, Karmazina IV, Meltseva EM. [Rehabilitation of the immune system in children treated for cancer pathology, at the stage of spa treatment]. Vestnik fizioterapii i kurortologi. 2016;3:4-12. Russian. URL: https://cyberleninka.ru/article/n/reabilitatsiya-immunnoy-sistemy-u-detey-prolechennyh-po-povodu-onkopatologii-na-etape-sanatorno-kurortnogo-lecheniya

Kyrtych LP, Dobra PP., Dobra LP. [The use of mineral waters at certain pathologies: Blood diseases]. editorors EO Kolesnyk, KD Babova. Mineralni vody Ukrainy. Kyiv: Kupriianova; 2005. p. 308.

Chechelnickaya SM, Rumyancev AG, Kasatkin VN, Karelin AF, Zhukovskaja EV, Borodina ID, Baerbah AV, Nikulin VA, Kolemasov IS. [Peculiarities of the physical status of children aged 4-18 treated for hemoblastosis and cns tumors]. Pediatriya. 2019;98(2):227-34. Russian. doi: https://doi.org/10.24110/0031-403X-2019-98-2-227-234

Volodin NN, Kasatkin VN, Cejtlin GJa, Sido¬renko LV, Mironova EV, Mitrakov NN, Miroshkin RB, Shheglova DD, Rumyancev AG. [Strategy of medical, psychological and social rehabilitation for children with haematological and oncological diseases]. Onkogema¬tologiya. 2015;1:7-15. Russian. doi: https://doi.org/10.17650/1818-8346-2015-1-7-15

Shapovalova HA. [Сomparative clinical characteristics of the children at different periods of remission of oncological diseases at the conditions of resort reha¬bilitation supported by their parents]. Aktualni problemy transportnoi medytsyny. 2017;3(49):98-104. Ukrainian. URI: http://dspace.nbuv.gov.ua/handle/123456789/140184

Shapovalova HA, Babov KD. [Dynamics of clinical and clinical-instrumental indices in children with accompanying diseases of the nervous system in the period of remission of cancer with additional administration of magnetotherapya]. Zdobutky klinichnoi i eksperymentalnoi medytsyny. 2018;2:207-10. Ukrainian. doi: https://doi.org/10.11603/1811-2471.2018.v0.i2.8927

Hu H, Shear D, Thakkar R, Thompson-Lastad A, Pinderhughes H, Hecht FM, Lown EA. Acupressure and Therapeutic Touch in Childhood Cancer to Promote Subjective and Intersubjective Experiences of Well-being During Curative Treatment. Glob Adv Health Med. 2019 Sep 30;8:2164956119880143. PMID: 31632842; doi: https://doi.org/10.1177/2164956119880143.

Kızmazoğlu D, Sarı S, Evim Sezgin M, Kantarcıoğlu A, Tüfekçi Ö, Demir Yenigürbüz F, Baytan B, Yılmaz Ş, Güneş AM, Ören H. Assessment of Health-Related Quality of Life in Pediatric Acute Lymphoblastic Leukemia Survivors: Perceptions of Children, Siblings, and Parents. Turk J Haematol. 2019 May 3;36(2):112-16. Epub 2018 Nov 6. PMID: 30401658; PMCID: PMC6516105. doi: https://doi.org/10.4274/tjh.galenos.2018.2018.0351

Batalha LM, Mota AA. Massage in children with cancer: effectiveness of a protocol. J Pediatr (Rio J). 2013 Nov-Dec;89(6):595-600. Epub 2013 Sep 13. doi: https://doi.org/10.1016/j.jped.2013.03.022

Thorsteinsson T, Larsen HB, Schmiegelow K, Thing LF, Krustrup P, Pedersen MT, Christensen KB, Mogensen PR, Helms AS, Andersen LB. Cardiorespiratory fitness and physical function in children with cancer from diagnosis throughout treatment. BMJ Open Sport Exerc Med. 2017 May 12;3(1):e000179. PMID: 28761697; PMCID: PMC5530132. doi: https://doi.org/10.1136/bmjsem-2016-000179

Cha S, Kim I, Lee SU, Seo KS. Effect of an Inpatient Rehabilitation Program for Recovery of Decon¬ditioning in Hematologic Cancer Patients After Chemotherapy. Ann Rehabil Med. 2018 Dec;42(6):838-45. Epub 2018 Dec 28. Erratum in: Ann Rehabil Med. 2019 Apr;43(2):239. PMID: 30613077; PMCID: PMC6325318. doi: https://doi.org/10.5535/arm.2018.42.6.838

Mustian KM, Alfano CM, Heckler C, Kleck¬ner AS, Kleckner IR, Leach CR, Mohr D, Palesh OG, Peppone LJ, Piper BF, Scarpato J, Smith T, Sprod LK, Miller SM. Comparison of Pharmaceutical, Psycholo¬gical, and Exercise Treatments for Cancer-Related Fati¬gue: A Meta-analysis. JAMA Oncol. 2017 Jul 1;3(7):961-8. PMID: 28253393; PMCID: PMC5557289. doi: https://doi.org/10.1001/jamaoncol.2016.6914

Cooper SL, Brown PA. Treatment of pediatric acute lymphoblastic leukemia. Pediatr Clin North Am. 2015 Feb 1;62(1):61-73. doi: https://doi.org/10.1016/j.pcl.2014.09.006

Darcy L, Granlund M, Enskär K, Björk M. The development of the clinical assessment tool "Health and Everyday Functioning in Young Children with Cancer". Child: Care, Health and Development. 2020 Jul;46(4):445-56. PMID: 31944353. doi: https://doi.org/10.1111/cch.12744.

Enskär K, Darcy L, Björk M, Knutsson S, Huus K. Experiences of Young Children With Cancer and Their Parents With Nurses' Caring Practices During the Cancer Trajectory. J Pediatr Oncol Nurs. 2020 Jan/Feb;37(1):21-34. Epub 2019 Sep 17. PMID: 31526068. doi: https://doi.org/10.1177/1043454219874007.

Gholman RR, Felemban EH, El Meligy OA. Dental Rehabilitation of a Child with Acute Lymphocytic Leukemia: A Case Report. Int J Clin Pediatr Dent. 2019 Nov-Dec;12(6):582-586. PMID: 32440080; PMCID: PMC7229377.

doi: https://doi.org/10.5005/jp-journals-10005-1664.

Wasilewska E, Kuziemski K, Niedoszytko M, Kac¬zorowska-Hać B, Niedzwiecki M, Małgorzewicz S, Jassem E. Impairment of lung diffusion capacity-a new consequence in the long-term childhood leukaemia survivors. Ann Hematol. 2019 Sep;98(9):2103-2110. Epub 2019 Jul 2. PMID: 31267177; PMCID: PMC6700051. doi: https://doi.org/10.1007/s00277-019-03745-4.

Jamal Saker, Simindokht Zarrati. Rehabilitation of Maxillary Defect for Adolescent Acute Lymphoblastic Leukemia (ALL) Patient with Acrylic Obturator. J Child Adolesc Dent. 2019;1(1):555552. URL: https://juniperpublishers.com/jocad/JOCAD.MS.ID.555552.php

Lemko IS, Haysak MO, Dychka LV. Quantitative evaluation of alkalinizing features of natural mineral waters of Transcarpathia. Balneoresearch Journal. 2020:11(2);174-9. doi: https://doi.org/10.12680/balneo.2020.336

Timilshina N, Breunis H, Tomlinson GA, Brand¬wein JM, Buckstein R, Durbano S, Alibhai SMH. Long-term recovery of quality of life and physical function over three years in adult survivors of acute myeloid leukemia after intensive chemotherapy. Leukemia. 2019 Jan;33(1):15-25. Epub 2018 Jun 8. PMID: 29884902. doi: https://doi.org/10.1038/s41375-018-0162-5

Shin ES, Seo KH, Lee SH, Jang JE, Jung YM, Kim MJ, Yeon JY. Massage with or without aromatherapy for symptom relief in people with cancer. Cochra¬ne Database Syst Rev. 2016 Jun 3;(6):CD009873. PMID: 27258432. doi: https://doi.org/10.1002/14651858.CD009873.pub3.

Müller C, Krauth KA, Gerß J, Rosenbaum D. Physical activity and health-related quality of life in pediatric cancer patients following a 4-week inpatient rehabilitation program. Support Care Cancer. 2016 Sep;24(9):3793-802. Epub 2016 Apr 7. PMID: 27056572.

doi: https://doi.org/10.1007/s00520-016-3198-y

Ospina Lopez PA. Physical Therapy Interventions for Children and Adolescents with Cancer: Collating the Evidence from Research and Clinical Practice: A thesis submitted in partial fulfilment of the requirements for the degree of Master of Science in rehabilitation science. University of Alberta, Canada, 2018. p. 220 doi: https://doi.org/10.7939/R3JD4Q46V

Braam KI, van der Torre P, Takken T, Veening MA, van Dulmen-den Broeder E, Kaspers GJ. Physical exercise training interventions for children and young adults during and after treatment for childhood cancer. Cochrane Database Syst Rev. 2016 Mar 31;3(3):CD008796. CD008796.pub3. PMID: 27030386; PMCID: PMC6464400. doi: https://doi.org/10.1002/14651858.

Simioni C, Zauli G, Martelli AM, Vitale M, Ultimo S, Milani D, Neri LM. Physical training interven¬tions for children and teenagers affected by acute lympho¬blastic leukemia and related treatment impairments. Oncotarget. 2018 Mar 30;9(24):17199-17209. PMID: 29682216; PMCID: PMC5908317.

doi: https://doi.org/10.18632/oncotarget.24762.

Ravens-Sieberer U, Bullinger M. KINDLR English Questionnaire for Measuring Health-Related Quality of Life in Children and Adolescents. Revised Version: Manual; 2000. p. 23. Available from: https://www.kindl.org/app/download/6175836884/ManEnglish.pdf?t=1338645880

Jepsen LO, Friis LS, Hoybye MT, Marcher CW, Hansen DG. Rehabilitation during intensive treatment of acute leukaemia including allogenic stem cell trans¬plantation: a qualitative study of patient experiences. BMJ Open. 2019 Nov 14;9(11):e029470. PMID: 31727647; PMCID: PMC6886906. doi: https://doi.org/10.1136/bmjopen-2019-029470

Ibanez K, Espiritu N, Souverain RL, Stimler L, Ward L, Riedel ER, Lehrman R, Boulad F, Stubblefield MD. Safety and Feasibility of Rehabilitation Interventions in Children Undergoing Hematopoietic Stem Cell Transplant With Thrombocytopenia. Arch Phys Med Rehabil. 2018 Feb;99(2):226-33. Epub 2017 Aug 12. PMID: 28807693; PMCID: PMC6342002. doi: https://doi.org/10.1016/j.apmr.2017.06.034.

Silva NB, Osório FL. Impact of an animal-assisted therapy programme on physiological and psychosocial variables of paediatric oncology patients. PloS One. 2018 Apr 4;13(4):: PMC5884536. doi: https://doi.org/10.1371/journal.pone.0194731

Tanner LR, Hooke MC. Improving body function and minimizing activity limitations in pediatric leukemia survivors: The lasting impact of the Stoplight Program. Pediatr Blood Cancer. Epub 2019 Jan 4. PMID: 30609245. 2019 May;66(5):e27596. doi: https://doi.org/10.1002/pbc.27596

Published

2021-12-20

How to Cite

1.
Lukashchuk S, Lemko O. Possibilities of rehabilitation treatment of children with lymphoblastic leukemia (literary review). Med. perspekt. [Internet]. 2021Dec.20 [cited 2024Apr.27];26(4):39-47. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/248084

Issue

Section

THEORETICAL MEDICINE