Challenges in preoperative diagnosis of glossopharyngeal nerve schwannoma: own findings analysis
Keywords:cerebellopontine angle, jugular foramen, vestibular schwannoma, glossopharyngeal schwannoma, cranial nerves caudal group schwannoma, diagnosis, clinical picture, cranial nerves
Medical history, disease onset, clinical symptoms, and results of neuroimaging of 14 glossopharyngeal schwannoma patients, who were examined and treated in the Subtentorial Neurooncology Department of the State Institution, Romodanov Institute of Neurosurgery of the NAMS of Ukraine (8 patients) and the Neurosurgery Department No. 2 of the Municipal Enterprise, Mechnikov Dnipropetrovsk Regional Clinical Hospital of Dnipropetrovsk Regional Council (6 patients) in 2018 to 2021 have been analyzed in details. The study inclusion criteria were as follows: patient’s age over 18, presence of unilateral primary glossopharyngeal nerve schwannoma. Our study showed that most of clinical signs and symptoms of the glossopharyngeal nerve schwannoma are associated with otolaryngological disorders (such as hearing loss, tinnitus, hoarseness, or dizziness) or cerebellar disorders (such as ataxia, nystagmus, or dizziness). Neuroimaging cerebellopontine angle tumors diagnosis must include brain computed tomography (with mandatory assessment of the state of jugular foramen and internal auditory canal) and IV contrast brain magnetic resonance tomography and inclusion of high-resolution sequences, gradient echo (3D CISS, DRIVE, TRUFFI, B-FFE) with the aim of better visualization and differentiation of various cerebellopontine angle cranial nerves. The study demonstrates the complexity of a reliable preoperative diagnosis when using standard diagnostic tools. Preoperative jugular foramen and cerebellopontine angle tumors diagnosis should be based on a systematic approach and include a comparison of results of comprehensive clinical and instrumental examination and neuroimaging studies.
Antomonov MYu. [Mathematical processing and analysis of biomedical data]. Kyiv: Medinform; 2018. p. 579. Russian. Available from: https://www.olx.ua/.../antomonov-m-yu-monografya
Lemmerling M, de De Foer B, editors. Imaging of the Jugular Foramen. Berlin: Springer; 2015. p. 380. doi: https://doi.org/10.1007/978-3-642-17896-2
Misra B, Kankane V, Warade A. Nonvestibular schwannoma tumors in the cerebellopontine angle: A single-surgeon experience. Asian Journal of Neurosurgery. 2019;14(1):154. doi: https://doi: 10.4103/ajns.AJNS_335_17
Zeng X, Li D, Hao S, Wang L, Tang J, Xiao X, et al. Long-Term Functional and Recurrence Outcomes of Surgically Treated Jugular Foramen Schwannomas: A 20-Year Experience. World Neurosurgery. 2016;86:134-46. doi: https://doi:10.1016/j.wneu.2015.09.104
Sedney C, Nonaka Y, Bulsara K, Fukushima T. Microsurgical Management of Jugular Foramen Schwannomas. Neurosurgery. 2012;72(1):42-46. doi: https://doi:10.1227/NEU.0b013e3182770e74
Wang X, Long W, Liu D, Yuan J, Xiao Q, Liu Q. Optimal surgical approaches and treatment outcomes in patients with jugular foramen schwannomas: a single institution series of 31 cases and a literature review. Neurosurgical Review. 2019;43(5):1339-50. doi: https://doi:10.1007/s10143-019-01165-6
Ryu S, Lee J, Park K, Choi J, Kong D, Nam D, et al. Optimal treatment of jugular foramen schwannomas: long-term outcome of a multidisciplinary approach for a series of 29 cases in a single institute. Acta Neurochirurgica. 2017;159(8):1517-27. doi: https://doi:10.1007/s00701-017-3230-0
Samii M, Alimohamadi M, Gerganov V. Surgical Treatment of Jugular Foramen Schwannoma. Neurosurgery. 2015;77(3):424-32. doi: https://doi:10.1227/NEU.0000000000000831
Sirko A. Surgical Treatment of Caudal Cranial Nerves Schwannomas: Literature Review and Analysis of Own Clinical Observations. Neurology & Neuroscience. 2019;3(4). doi: https://doi:10.33552/ANN.2019.03.000569
Kano H, Meola A, Yang H, Guo W, Martínez-Alvarez R, Martínez-Moreno N, et al. Stereotactic radiosurgery for jugular foramen schwannomas: an interna¬tional multi¬center study. Journal of Neurosurgery. 2018;129(4):928-36. doi: https://doi:10.3171/2017.5.JNS162894
Nowak A, Dziedzic T, Czernicki T, Kunert P, Marchel A. Surgical treatment of jugular foramen schwannomas. Neurologia i Neurochirurgia Polska. 2014;48(3):188-95. doi: https://doi:10.1016/j.pjnns.2014.05.004
Zemskova O, Skobska O, Malysheva O, Malysheva T, Pylypas O, Gudkov V. Technical considerations in a glossopharyngeal schwannoma. Interdisciplinary Neuro¬surgery. 2021;23:100969. doi: https://doi.org/10.1016/j.inat.2020.10096910
Touska P, Juliano A. Temporal Bone Tumors. Neuroimaging Clinics of North America. 2019;29(1):145-72. doi: https://doi:10.1016/j.nic.2018.09.007
Tradecki M, Kobylańska M. Patient with glossopharyngeal schwannoma of cerebellopontine angle. Pol Merkur Lekarski. 2018 Aug 29;45(266):75-76. PMID: 30240373
How to Cite
Copyright (c) 2022 Medicni perspektivi
This work is licensed under a Creative Commons Attribution 4.0 International License.
Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.
Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.