The results of using Blue cap® foam for skin care with signs of xerosis




xerosis, atopic dermatitis, acne, seborrheic dermatitis, rosacea, correction of skin dryness, emollients


A significant increase in the severity of clinical manifestations of various dermatoses accompanied by dry skin often increases the feeling of discomfort and itching of the skin, significantly reducing the patient's quality of life. This leads to the search for effective ways to correct the dryness of the skin and maintain the proper functioning of the epidermal barrier of the skin in various dermatoses. The aim of the study was to study the effect of using a combined emollient, which includes components of a classic emollient (with the inclusion of ceramides and substances with moisturizing and softening effects), as well as substances with antiseptic and fungistatic effects. The results of treatment of 100 patients with skin diseases and conditions accompanied by dry skin and itching were analyzed. The study group included patients with acne undergoing treatment with retinoids and external preparations with an irritating effect, patients with atopic dermatitis in remission, patients with seborrheic dermatitis, rosacea, follicular hyperkeratosis, and skin xerosis. Using the method of corneometry, the dynamics of changes in skin hydration during the use of a combined moisturizer and changes in the indicators of the dermatological index of the quality of life of patients were studied. The data obtained showed a pronounced increase in skin hydration in terms of corneometry after 2 weeks of using an emollient (by an average of 31.6 units or 160%), and after a month of observation, the changes amounted to 36.7 conv. units, i.e. increased by 185%, which proves the effectiveness of using Blue cap® foam to normalize skin hydration. The level of the dermatological index of quality of life during this period decreased from 9.9±0.2 to 7.2±0.2 points, i.e. by 2.7 points or 27%,what also indicates an improvement in the subjective attitude of patients and promotion quality of life of patients. In the course of the study, a significant improvement in skin hydration when using the combined Blue cap® foam to correct signs of skin xerosis was proven. In the case of dermatoses accompanied by itching associated with dry skin, a marked reduction in itching was noticed, as well as a significant improvement in the quality of life of the patient after a month of using the combined moisturizer.


Vyumvuhore RR, Michael-Jubeli R, Verzeaux L, Boudier D, Le Guillou M, Bordes S, et al. Lipid organization in xerosis: the key of the problem? Int J Cosmet Sci. 2018;40(6):549-54. doi:

Kovalova TM, Polovko NP. [Xerosis: Causes and Review of the Progressive Correction]. Collection of scientific works of NMAPE named after PL Shupyk. 2015;24(2):405-09. Ukrainian.

Kaliuzhnaia LD. [Modern external therapy for dry aging skin]. Ukr. J. dermatol., venerol., kosmetol. 2005;18(3):33-35. Ukrainian.

Sviatenko TV, Kharitonova OG, Starostina OA. [Complex therapy and rehabilitation of patients with rosacea]. Dermatolohiia ta venerolohiia. 2014;(4):93-99. Ukrainian.

Sviatenko TV, Starostina OA. [Analysis of the antipruritic effect of the combined use of desloratadine and dimethindemaleate in the treatment of allergic dermatosis in children]. Health of Ukraine. 2021;16(4):46-52. Ukrainian.

Arora D, Garg S. Skin Care of Acne Vulgaris in Sensitive Skin. The Sensitive Skin: Treatment Modalities and Cosmeceuticals. 2019:3.

Guanti MB, Bonzano L, Rivi M, Alicandro T, Liberati S, Hebert AA, et al. Efficacy and Safety of an Antioxidant-Enriched Medical Device for Topical Use in Adults with Eczematous Dermatitis. Dermatology and Therapy. 2022;12(4):1015-25. doi:

Huang Y-x, Li J, Zhao Z-x, Zheng B-l, Deng Y-x, Shi W, et al. Effects of skin care habits on the development of rosacea: a multi-center retrospective case-control survey in Chinese population. PLoS ONE. 2020;15(4):e0231078. doi:

Stettler H, Crowther JM, Brandt M, Lu B, Boxshall A, de Salvo R, et al. Targeted dry skin treatment using a multifunctional topical moisturizer. International Journal of Cosmetic Science. 2021;43(2):191-200. doi:

Yosipovitch G, Misery L, Proksch E, Metz M, Ständer S, Schmelz M. "Skin Barrier Damage and Itch: Review of Mechanisms, Topical Management and Future Directions." Acta Derm Venereol 2019;99:1201-9. doi:

Sutton E, Shaw AR, Ridd MJ, Santer M, Roberts A, Baxter H, et al. How parents and children evaluate emollients for childhood eczema: a qualitative study. British Journal of General Practice. 2022;72(719):e390-e7. doi:

Koliadenko VG, Chernyshov PV. [Indicators of the quality of life in dermatological ailments]. Ukr. J. dermatol., venerol., kosmetol. 2005;2:11-14. Ukrainian.

Peacock J. Peacock P. Oxford Handbook of Medical Statistics. Oxford medical handbook; 2010. doi:

Cekiera A, Popiel Ja, Siemieniuch M, Jaworski Z, Slowikowska M, Siwinska N, et al. The examination of biophysical parameters of the skin in Polish Konik horses. PloS ONE. 2021;16(6):e0250329. doi:

Moore DJ, Rawlings AV. The chemistry, function and (patho) physiology of stratum corneum barrier ceramides. International journal of cosmetic science. 2017;39(4):366-72. doi:

Zelenkova H, Pavlickova D. Effectiveness of activated piroctone olamine in the treatment of psoriasis and seborrheic dermatitis. Dermatology DOST Svidnik. 2022;1:43.

Baurecht H, et al. Epidermal lipid composition, barrier integrity, and eczematous inflammation are associated with skin microbiome configuration. Journal of Allergy and Clinical Immunology. 2018;141(5):1668-76.e16 doi:

Lefèvre-Utile A, Braun C, Haftek M, Aubin F. Five functional aspects of the epidermal barrier. International Journal of Molecular Sciences. 2021;22(21):11676. doi:

[Expert conclusion No. K-486]. Kyiv: Chamber of Commerce and Industry [Internet]. 2021 April 27. Ukrainian. Available from:

Batpenova GR, Tsoi NO. [The results of a clinical study and assessment of the effectiveness of the casting of Blue Cap® Foam]. Theses of Astana cal University. 2022:4-6. Ukrainian.




How to Cite

Svyatenko T, Starostina O, Zakharov S, Solovyiova S. The results of using Blue cap® foam for skin care with signs of xerosis. Med. perspekt. [Internet]. 2022Dec.29 [cited 2024Apr.13];27(4):177-84. Available from: