Limited impact of roselle flower extract on protein carbonyl levels after physical exercise in healthy men

N.  Ayubi; A.  Rusdiawan; S. Hartoto; J.C.  Wibawa; A.Z.  Rizki; A.  Afandi; A.P.S.  Wardani; M.F.  Halip; P.B.D.  Jr

doi:10.26641/2307-0404.2025.1.325371

Автор(и)

N. Ayubi Universitas Negeri Surabaya, Surabaya, Jawa Timur, 60213, Індонезія https://orcid.org/0000-0002-5196-6636
A. Rusdiawan Universitas Negeri Surabaya, Surabaya, Jawa Timur, 60213, Індонезія https://orcid.org/0000-0001-5388-7061
S. Hartoto Universitas Negeri Surabaya, Surabaya, Jawa Timur, 60213, Індонезія https://orcid.org/0000-0003-1310-3570
J.C. Wibawa STKIP PGRI Trenggalek, Jl. Supriyadi str., 22, Trenggalek, Jawa Timur, 66319, Індонезія
A.Z. Rizki Universitas Negeri Surabaya, Surabaya, Jawa Timur, 60213, Індонезія https://orcid.org/0009-0006-7025-7209
A. Afandi Universitas Negeri Surabaya, Surabaya, Jawa Timur, 60213, Індонезія https://orcid.org/0009-0009-7161-3852
A.P.S. Wardani Universitas Negeri Surabaya, Surabaya, Jawa Timur, 60213, Індонезія https://orcid.org/0009-0009-2829-4075
M.F. Halip Universitas Negeri Surabaya, Surabaya, Jawa Timur, 60213, Індонезія https://orcid.org/0000-0002-7208-6048
P.B.D. Jr Mariano Marcos State University, Quiling Sur, 16, Batac, Ilocos Norte, 2906, Філіппіни https://orcid.org/0000-0002-4249-6126

DOI:

https://doi.org/10.26641/2307-0404.2025.1.325371

Ключові слова:

roselle flower extract, oxidative stress, protein carbonyl, antioxidants, exercise-induced muscle damage

Анотація

Exercise-induced oxidative stress can lead to muscle damage, with protein carbonyls serving as a key biomarker of oxidative modification in proteins. Roselle flower extract contains polyphenols with potential antioxidant properties that may reduce oxidative damage after physical exercise. This study investigated whether post-exercise supplementation of roselle flower extract reduces protein carbonyl levels. A randomized controlled trial with a parallel group pre-test/post-test design was conducted, comparing a placebo group with a treatment group receiving 500 mg of roselle flower extract. The extract did not result in a statistically significant reduction in protein carbonyl levels (p>0.05). However, a non-significant decreasing trend was observed, suggesting that future studies should explore larger sample sizes and longer intervention periods to assess potential cumulative effects. Further studies should explore the effects of higher doses of roselle flower extract (e.g., >500 mg/day) and chronic supplementation over several weeks to determine its long-term impact on markers of oxidative stress.

Посилання

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