Ways to reduce complications during open adenomectomy in patients with BPH using modified removable sutures

Authors

DOI:

https://doi.org/10.26641/2307-0404.2025.3.340756

Keywords:

open adenomectomy, blood loss, complications, modified removable sutures, benign prostatic hyperplasia

Abstract

The study was aimed at evaluating the effectiveness of using a modified removable purse-string suture with polyurethane tubing to reduce complications after transvesical adenomectomy in patients with benign prostatic hyperplasia. A total of 60 pa­tients participated in the study. They were distributed into two groups: 30 patients in the main group, where the improved method using a polyurethane tube was used, and 30 patients in the control group, where the standard technique without removable suture was used. The comparison showed that in the main group, the average volume of blood loss in the first 48 hours was 240 [200-280] ml, which was significantly less than in the control group, where it reached 385 [320-450] ml (p<0.05). Furthermore, in patients of the main group, the haemoglobin level on the first day after surgery was higher – 112.3 [103.9-120.7] g/l compared to 104.5 [96.9-112.1] g/l in the control group (p<0.05). This indicated better control of blood loss. The incidence of complications such as bleeding and inflammation was lower in the main group, 6% versus 20% in the control group (p<0.05). Additionally, the level of C-reactive protein on the third day after surgery in the main group was 12.3 [10.1-14.5] mg/l, while in the control group, it was significantly higher – 17.6 [14.1-21.1] mg/l (p<0.05). Thus, the use of removable purse-string suture with polyurethane tube demonstrated its effectiveness in reducing blood loss and complication rate, providing better recovery after surgery in patients with benign prostatic hyperplasia. The findings demonstrate that the use of a modified removable purse-string suture with polyurethane tubing effectively reduces blood loss, enhances haemostasis, and lowers the incidence of postoperative complications in patients undergoing transvesical adenomectomy for benign prostatic hyperplasia. Additionally, this technique contributes to a shorter recovery period and improved haemoglobin levels, indicating better overall postoperative outcomes.

References

Wang H, Tang R, Luo S, Hou H, Liu J, Liu M, et al. Association of life’s crucial 9 score with benign prostatic hyperplasia: A cross-sectional study. J Health Popul Nutr. 2025;44(163):1-11. doi: https://doi.org/10.1186/s41043-025-00925-z

Pérez MLF, Becerra AJM, Delgado MGR. Post-operative complications in patients with benign prostatic hyperplasia according to surgical technique. Rev Cub Med Mil. [Internet]. 2021 [cited 2025 Jun 7];50(4):e02101615. Available from: https://www.medigraphic.com/pdfs/revcubmedmil/cmm-2021/cmm214j.pdf

Baktybek Uulu A, Usupbaev A, Ismatov B, Abibillaev D, Konurbaev B. Comparative outcomes of retro-pubic versus transvesical open adenomectomy in benign prostatic hyperplasia: A retrospective cohort study. Heart Vessel Transplant. 2025;9. doi: https://doi.org/10.24969/hvt.2025.580

Sfredo LR, de Oliveira IC, Novakoski GK, Digner IS, Silva IVM, Lacerda DAM, et al. Comparative analysis between open transvesical and laparoscopic ade-nomectomy in the treatment of benigne prostatic hyperplasia in a tertiary hospital in Curitiba-PR: a retrospective study. Rev Col Bras Cir. 2023;50:e20233450. doi: https://doi.org/10.1590/0100-6991e-20233450-en

Akassimadou N, Avion KP, Aguia B, Zouan F, Alloka V, Kamara BS, et al. Post-operative complications of transvesical prostatic adenomectomy at Bouake Teaching Hospital: Epidemiological, diagnostic and therapeutic aspects. Open J Urol. 2023;13(9):345-52. doi: https://doi.org/10.4236/oju.2023.139039

Fariñas Martínez JA, Laffita Estévez S, Téllez Pérez R, Ortega Rodríguez D. Complications of adeno¬mec-tomy in the elderly. Rev Electron Zoilo. 2013;38(5):1-10.

Berthe A, Ballo B, Drago AA, Togola A, Sissoko I, Ouattara AD, et al. Postoperative complications of transvesical adenomectomy of the prostate in the urology department of the centre Hospitalier Universitaire GABRIEL TOURE in Bamako. East Afr Sch J Med Sci. 2024;7(2):78-82. doi: https://doi.org/10.36349/easms.2024.v07i02.008

van der Sanden WMH, Fossion LMCL, de Laet K. Endoscopic transvesical adenomectomy of the prostate, a new minimal invasive approach for large benign prostate hyperplasia. A description of the technique and the results of the first 40 patients. Urology. 2019;125:174-8. doi: https://doi.org/10.1016/j.urology.2018.12.031

Noguera RS, Rodríguez RC. Open adenomectomy: past, present and future. Curr Opin Urol. 2008;18(1):34-40. doi: https://doi.org/10.1097/mou.0b013e3282f0d625

Shapiro SS, Wilk MB. An analysis of variance test for normality (complete samples). Biom. 1965;52(3-4):591-611. doi: https://doi.org/10.1093/biomet/52.3-4.591

Cochran WG. The χ² Test of Goodness of Fit. Ann Math Statist. 1952;23(3):315-45. doi: https://doi.org/10.1214%2Faoms%2F1177729380

World Medical Association. World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191-4. doi: https://doi.org/10.1001/jama.2013.281053

The Clavien-Dindo Classification [Internet]. 2025 [cited 2025 Jun 7]. Available from: https://www.assessurgery.com/clavien-dindo-classification/

Gorety M, Winarto E, Utama JEP. The ‘Maria screening instrument’ for post-open prostatectomy bleeding risk: A qualitative study. Hearty J Public Health. 2024;12(3):604-10. doi: https://doi.org/10.32832/hearty.v12i3.16719

Borkowski T, Michalec J, Kuzaka B, Borkowski A, Radziszewski P. Internal optical urethrotomy is the treatment of choice in stenosis of the bladder neck after open prostate adenectomy. Wideochir Inne Tech Maloinwazyjne. 2019;14(3):427-32. doi: https://doi.org/10.5114/wiitm.2019.82686

El Alaoui A, El Boté H. Giant prostatic adenoma. Pan Afr Med J. 2018;30:256. doi: https://doi.org/10.11604/pamj.2018.30.256.12142

Dell'Atti L, Galeotti R. Pseudoaneurysm secondary to transvesical prostatectomy. Indian J Urol. 2016;32(2):164-5. doi: https://doi.org/10.4103/0970-1591.174783

Bove AM, Altobelli E, Sergi F, Buscarini M. Robot-assisted laparoscopic radical prostatectomy after previous open transvesical adenomectomy. J Robot Surg. 2014;8(1):85-8.

doi: https://doi.org/10.1007/s11701-013-0392-5

Mdivnishvili M, Khuskivadze N, Khuskivadze A. Giant benign prostatic hyperplasia: A case report. Cureus. 2024;16(5):e61295. doi: https://doi.org/10.1016/j.eucr.2019.101051

Cornejo-Dávila V, Mayorga-Gómez E, Palmeros-Rodríguez MA, Uberetagoyena-Tello de Meneses I, Garza-Sáinz G, Osornio-Sánchez V, et al. Role of transvesical adenomectomy in treatment of prostate hyperplasia: 7 years of experience at a single center in Mexico City. Rev Mex Urol. 2015;75(1):14-9. doi: https://doi.org/10.1016/j.uromx.2014.11.002

Vale L, Fossion L. Endoscopic transvesical adenomectomy of the prostate, a new minimally invasive approach for large benign prostatic hyperplasia. What has our experience taught us? Cent European J Urol. 2020;73(4):482-9. doi: https://doi.org/10.5173/ceju.2020.0053.R3

Horovyi VI, Shaprynskyi VO, Kapshuk OM, Sosnin MD, Tsekrovnyuk RG, Moraru-Burlesku RP, et al. Transcervical transvesical prostatectomy in patients with benign prostate hyperplasia. Health Man. 2024;3:56-62. doi: https://doi.org/10.30841/2786-7323.3.2024.316663

Gnammi LR, Cissé D, Gamamou VA, Kanté D, Diawo Bah M, Akinocho EM, et al. Comparative study of transvesical and retropubic prostatic adenomectomies in the Urology-Andrology Department of Ignace Deen University Hospital Center. Open J Urol. 2024;14(4):227-43. doi: https://doi.org/10.4236/oju.2024.144023

Coulibaly N, Ackoundou-N'guessan C, Ngues-san Y, Aye Y, Guei M, Toure D, et al. Morbidity and mortality after transvesical prostatic adenomectomy at the University Hospital of Libreville. A report of 68 cases. Uro-Andro. [Internet]. 2017[cited 2025 Jun 7];1(8):362-6. Available from: https://revue-uroandro.org/index.php/uro-andro/article/view/113

Botcho G, Kpatcha TM, Tengue K, Dossouvi T, Sewa EV, Simlawo K, et al. Morbidity and mortality after open prostatectomy for benign prostatic hyperplasia by transvesical approach at the Teaching Hospital of Kara, Togo. Afr J Urol. 2018;24(4):353-8. doi: https://doi.org/10.1016/j.afju.2018.01.008

Downloads

Published

2025-09-29

How to Cite

1.
Botalaev B, Usupbaev A, Abdykalykov M, Zhumagaziev T, Mailubashev M. Ways to reduce complications during open adenomectomy in patients with BPH using modified removable sutures. Med. perspekt. [Internet]. 2025Sep.29 [cited 2025Dec.5];30(3):140-51. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/340756

Issue

Section

MEDICINE