Drug correction of intestinal motility disorders in intensive care in the postoperative period in surgical patients.

Authors

  • L. V. Novitskaya-Usenko
  • S. G. Dyomin

DOI:

https://doi.org/10.26641/2307-0404.2015.1.40238

Keywords:

postoperative intestinal ileus, L-arginine, circulatory dynamics, inflammation

Abstract

Aim: improving the results of the complex treatment of patients with surgical pathology of abdominal organs by improving prevention and treatment of motor-evacuation disorders of the gastrointestinal tract in the postoperative period. Results: the article presents data on the use of metoclopramide, L- ar­ginine, simethicone for the prevention of postoperative dysmotility development. It is proved that L-arginine use reduces the effects of peripheral vasospasm by improving microcirculation of the intestinal wall and this leads to a more rapid recovery of motor-evacuation function of the gastrointestinal tract.

Author Biographies

L. V. Novitskaya-Usenko

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

S. G. Dyomin

MI «Dnipropetrovsk city clinical hospital N 6» of Dnipropetrovsk Regional Council 2
Dnipropetrovsk, 49000, Ukraine

References

Kalinin AB., Butrova LI. [Espumizan use for normalization of intestinal motor function in post-operative paresis]. Consilium medicum. Gastroenterologiya. 2006;2:64-68. Russian. 2. Kolosovskikh A, Kan SL, Churlyaev YuA, Zoloeva OS. [Functional state of intestinal microcirculation in diffuse peritonitis]. Obshchaya reanimatologiya. 2012;8(2):33-37. Russian. 3. Ngowe MN, Eyenga MN, Ngowe VC. Chewing gum reduces postoperative ileus after open appendectomy. Acta Chir Belg. 2010;110:195–9. 4. Elsner JL, Smith JM, Ensor CR. Intravenous neo¬stigmine for postoperative acute colonic pseudo-obstruc¬tion. Ann Pharmacother. 2012;46:430-5. 5. Kuruba R, Fayard N, Snyder D. Epidural anal¬gesia and laparoscopic technique do not reduce incidence of prolonged ileus in elective colon resections. Am J Surg. 2012;204:613-8. 6. Johnson MD, Walsh RM. Current therapies to shor¬ten postoperative ileus. Cleve Clin J Med. 2009;76:641–8. 7. van Bree SH, Nemethova A, Cailotto C, Gomez-Pinilla PJ. New therapeutic strategies for postoperative ileus. Nat Rev Gastroenterol Hepatol. 2012;9(11):675-83. 8. Procacciante F, De Luca M, Abilaliaj V. Post-operative ileus in hemicolectomy for cancer: open versus laparoscopic approach.Ann Ital Chir. 2013;84:557-62. 9. Gao Z, Muller MH, Karpitschka M, Mittler S. Role of the vagus nerve on the development of post¬ope¬rative ileus. Langenbecks Arch Surg. 2010;395:407-11.

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Published

2015-03-16

How to Cite

1.
Novitskaya-Usenko LV, Dyomin SG. Drug correction of intestinal motility disorders in intensive care in the postoperative period in surgical patients. Med. perspekt. [Internet]. 2015Mar.16 [cited 2024Nov.24];20(1):41-8. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/40238

Issue

Vol. 20 No. 1 (2015)

Section

CLINICAL MEDICINE

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