Reparation effects of vacuum wound therapy in patients with diabetic foot syndrome.

Authors

  • A. M. Besedin

DOI:

https://doi.org/10.26641/2307-0404.2015.3.53694

Keywords:

vacuum therapy, diabetic foot, treatment of wounds

Abstract

Vacuum Therapy (Vacuum-assisted closure, VAC) - a method of complex therapy which is used to improve the healing of both acute chronic wounds in patients with diabetic foot syndrome. Due to widespread introduction of this technique, unique cell, extracellular and general effects of its use in the treatment of patients with purulent-necrotic complications of diabetic foot syndrome, a technique of vacuum wound therapy has been successfully used in many surgical departments of Ukraine. Despite the diversity of the clinical effects of VAC-therapy and appearance of number of publications, in the domestic and foreign literature physiological basis of this method have not been studied completely. The effectiveness of vacuum therapy explain: the reduction of the size of the wound, the stabilization of the wound environment (due to the removal of inflammatory mediators and cytokines), microdeformation and remodeling of cell, rows reduction of edema, reduction of bacterial contamination, etc. At the same time, mechanisms of blood flow enhancement at different duration of VAC-therapy use, remain unclear its effect on the third phase of wound healing process as well.

Author Biography

A. M. Besedin

ME «Dnipropetrovsk City Multidisciplinary Hospital N 4» DRC
Department of septic surgery
Blygnia str., 31, Dnipropetrovsk, 49000, Ukraine

References

Besedin OM, Malyk YY, Karpenko LI, Sotnikov SV, Jwanski LV, Pundik GM. [Vacuum instillation the-rapy in patients with diabetic foot syndrome ]. Clinical Surgery. 2014;11(3):8-10. Ukrainian. 2. Obolensky VN, Semenistiy AY, Nikitin VG, Sy-chev D. [Vacuum therapy in the treatment of wounds and wound infections]. Russian medical journal. 2010;17(381):1064-72. Russian. 3. Vasylyuk SM, Krymets SA. [Surgical treatment of infected ulcers in patients with diabetic foot syn¬d¬rome]. Ukrainian journal of surgery. 2013;1(20):20-24. Ukrainian. 4. Zaitseva EL, Doronina LP, Silent RV, Voron-kov IA, Mitish VA, Tokmakova AY. [Influence of nega-tive pressure therapy on reparative processes in the soft tissues of the lower extremities in patients with neuro-pathic and neuroischemic form of diabetic foot synd¬ro-me]. Diabetes. 2014;3:113-21. Russian. 5. Zaitsev VM, Liflyandsky VG, Marinkin VI. [Ap-plied Medical Statistics] "Publishing House of the FOLIO". 2003;432. Russian. 6. Zaitseva EL, Tokmakova AY. [Vacuum therapy in the treatment of chronic wounds]. Diabetes. 2012;3:45-49. Russian. 7. Zaitseva EL, Tokmakova AY. [The role of growth factors and cytokines in the reparative processes in the soft tissues in patients with diabetes mellitus]. Diabe¬tes. 2014;(1):57-62. Russian. 8. Kutovoy AB, Kosulnykov SO, Tarnopolskyy SA, Karpenko SI Kravchenko KV. [Treatment of purulent wounds with vacuum]. Clinical Surgery. 2011;6:59-61. Russian. 9. Andros G, Armstrong D, Attinger C, et al. Con-sensus sta¬tement on negative pressure wound therapy for the mana¬ge¬ment of diabetic foot wounds. Vasc.Dis.Manage. 2006;1:1-32. 10. Bassetto F, Lancerotto L, Salmaso R, Pandis L, Pajardi G, Schiavon M, et al. Histological evolution of chronic wounds under negative pressure therapy. J. Plast. Reconstr. Aesthet. Surg. 2012;65(1):91–99. 11. Dinh T, Tecilazich F, Kafanas A, Doupis J, Gnar-dellis C, Leal E, et al. Mechanisms involved in the development and healing of diabetic foot ulceration. Diabetes. 2012;61(11):2937-47.

Downloads

Published

2015-09-23

How to Cite

1.
Besedin AM. Reparation effects of vacuum wound therapy in patients with diabetic foot syndrome. Med. perspekt. [Internet]. 2015Sep.23 [cited 2024Nov.13];20(3):106-12. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/53694

Issue

Vol. 20 No. 3 (2015)

Section

CLINICAL MEDICINE

License

Copyright (c) 2017 Medical Perspectives

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.

Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.