Modern possibilities of antisecretory therapy in children.

Authors

  • T. V. Yaroshevskaya
  • N. B. Sapa
  • N. N. Kramarenko
  • S. P. Degtyar

DOI:

https://doi.org/10.26641/2307-0404.2015.4.56137

Keywords:

children, chronic gastroduodenitis, antisecretory therapy, pantoprazole

Abstract

The article deals with the problem of antisecretory therapy in children with erosive gastric and duodenal lesions usingproton pump inhibitors. Taking into account low potential of side effects and drug interactions, pantoprazole was used for antisecretory therapy. Administration of preparation in two doses, one of which is in the form of intravenous infusion, from the first day of patients’ hospital stay led to the rapid relief or significant reduction of pain. In 86% of patients pain was completely controlled by day 7 of hospital stay. More than 90% of patients during therapy showed improvement of appetite and general well-being, reduction of dyspeptic symptoms (nausea, vomiting, belching). The proposed scheme of pantoprazole administration showed high efficacy and safety in chronic erosive gastroduodenitis therapy in children with severe pain.

Author Biographies

T. V. Yaroshevskaya

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine» 
Department of Propaedeutics of Children’s Diseases
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

N. B. Sapa

CI “Dnepropetrovsk Children’s City Clinical Hospital N2 DRC” 
Sverdlova str., 29, Dnepropetrovsk, 49101, Ukraine

N. N. Kramarenko

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine» 
Department of Propaedeutics of Children’s Diseases
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

S. P. Degtyar

CI “Dnepropetrovsk Children’s City Clinical Hospital N2 DRC” 
Sverdlova str., 29, Dnepropetrovsk, 49101, Ukraine

References

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Published

2015-11-25

How to Cite

1.
Yaroshevskaya TV, Sapa NB, Kramarenko NN, Degtyar SP. Modern possibilities of antisecretory therapy in children. Med. perspekt. [Internet]. 2015Nov.25 [cited 2024Dec.24];20(4):57-61. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/56137

Issue

Vol. 20 No. 4 (2015)

Section

CLINICAL MEDICINE

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