Microbiologic picture of microflora of female urogenital organs.

Authors

  • A. D. Dyudyun
  • N. M. Polion

DOI:

https://doi.org/10.26641/2307-0404.2016.1.63491

Keywords:

bacteria, colonization, lactobacilli, adhesion, normobiota, biotope

Abstract

In this report authors give  a detailed analysis of microorganisms that can contaminate mucous membranes of female urogenital system  in normal range and in the formation of certain dysbiotic position. The composition of microorganisms that colonize the mucous membrane of the urogenital tract depends on many exogenous and endogenous factors. The main microorganisms that provide colonizing resistance of vaginal biotop (VB) are lactobacilli and lactobacteria. The protective properties of lactobacillus are implemented by antagonistic activity and ability to produce lysozyme and hydrogen peroxide. L. acidophilus, L. spp.; Propionbacterium spp.; Fusobacterium spp.; Porphyromonas spp.; Prevotella spp.; S. epidermidis and S. Saprophyticus novobionrezistentni and Streptococcus spp. and others are of definite importance in supporting normobiots of mucous membranes of urogenital system of women. Decreasing number of lactobacilli and other microorganisms of normobiota leads to colonization of mucous membranes of the vagina with G.vaginalis, B.bivies, B.disiens, B.melaninigenius, Mobiluncus, E.coli, E.fecalis, S.epidermidis and development of clinical manifestation of VB. The authors show microscopic and bacteriological characteristics of microorganisms that form normal microbiota and pathological states. The development of basic subjects promotes increasing number of the known microorganisms, important in the development of VB.

Author Biographies

A. D. Dyudyun

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

N. M. Polion

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

References

Dashkevich VE, Davydova YuV. [Use of the drug Dalatsin vaginal cream in obstetric practice]. Ukr. med. chasopis. 2000;3:40-42. Ukrainian. 2. Plakhova KI, Gomberg MA, Atroshkina ME. [Examination of the spectrum microbial composition of vaginal contents using DNA chips]. Vtoroy Vseros. kon-gress dermatovenerologov: tez. nauch. rabot. 2007;162. Russian. 3. Kira EF. [Bacterial vaginosis]. SPb.: OOO «Neva-Lyuks». 2001;363. Russian. 4. Mal'tseva LI, Minnullina FF, Azizova AA. [Effi-cacy of "Yodoksid" in the treatment of bacterial vaginosis in women]. Ginekologiya. 2003;5(6):251-3. Russian. 5. Kafarskaya LI, Korshunova OV, Efimov BA. [Mic¬robial ecology of the vagina]. Mikrobiologiya. 2002;6:91-99. Russian. 6. Korshunov VM, Volodin NN, Efimov BA. [Va-ginal Microecology. Correction of vaginal microflora in dysbiosis]. 1999;80. Russian. 7. Nazarova EK, Gimmel'farb EI, Sozaeva LG. [Dysbacterioses of vagina: etiology, pathogenesis, clini-cal, picture laboratory diagnostics]. 2000;7. Russian. 8. Nikonov AP, Astsaturova OR. [Vulvovaginitis]. Gynecologya. 2002;4(3):122-5. Russian. 9. Kholta Dzh, Kriga N, Snita P. [The determinant of bacteria Burgi]. Mir, 1997;1:429. Russian. 10. Mel'nikov VA, Krasnova NA, Semenova NA. [Prospects for a new approach to the treatment of bacte-rial vaginosis and Candida vaginitis during the first trimester of pregnancy]. Sb. Materialov 9 Vseros. nauch. foruma «Mat' i ditya». 2007;164. Russian. 11. Plakhova KI. [Bacterial vaginosis: Treatment Protocol]. Venerolog. 2007;4:10-16. Russian. 12. Prilepskaya VN. [NovaRing - contraception, ana-tomy, sexology]. Ginekologiya. 2005;6:306-8. Russian. 13. Prilepskaya VN, Bayramova GR. [Etio¬patho¬ge-nesis, diagnostics and modern trends in the treatment of bacterial vaginosis]. Rus. med. zhurn. 2002;18:795-7. Russian. 14. Plakhova KI, Gomberg MA, Atroshkina ME. [Role of Atopobium vaginae in the recurrence of bacterial vaginosis]. Vestn. dermatologii i venerologii. 2007;5:9-13. Russian. 15. Shlyapnikov ME, Merkulova VI, Afanas'eva LV. [The role of, sexually transmitted infections and vaginal dysbiosis in the pathogenesis of postpartum endo¬myometritis]. Urgentnaya i rekonstruktivno-vosstano¬vitel'naya khirurgiya. 2007;3:88-92. Russian. 16. Rudakova EB. [Dysbiosis of vaginal and cervical pathology]. Genital'nye infektsii. 2006;1:52-55. Russian. 17. Serov VN, Tikhomirov AL, Oleynik ChG. Mo-dern understanding of bacterial vaginosis. Vopr. gine¬kolo-gii, akusherstva i perinatologii. 2005;4(1)66-71. Russian. 18. Sidorova IS. Borovkova EI. [The microflora of the genital tract of women of reproductive age]. Praktich. meditsina. 2007;80. Russian. 19. Sikerina OV, Serebrennikova KG, Tetelyuti-na FK. [Immune status in young pregnant women with bacterial vaginosis]. Materialy V Ros. foruma «Mat' i ditya». 2003;209-10. Russian. 20. Tkachenko LV. [Modern features of clinical pic-ture, diagnosis and treatment of urogenital infections]. Volgograd. 2004;36. Russian. 21. Dolgov GV, Abashin VG, Molchanov OL, Gay-voronskikh DI. [Specific treatment for bacterial vagino-sis]. Med. immunologiya. 2005;7(2-3):184. Russian. 22. Arzese AR, Tomasetig L, Botta GA. Detection of tetQ and ermF antibiotic resistance genes in prevotella and porphyromonas isolates from clinical specimens and resident microbiota of humans. J. Antimicrob. Chemother. 2000;45:577-82. 23. Goldacre MJ, Watt B. Vaginal microbial flora in normal young women. Brit. Med. J. 1999;1:1450-3. 24. Hillier SL, Holmes KK. Bacterial vaginosis. Sexually transmitted. 1999;547-60. 25. Leukorrhea and bacterial vaginosis as in-office predictors of cervical infection in high-risk women. Obstet. Gynecol. 2002;30(2):160-5. 26. Nugent RP, Krohn MA, Hillier SL. Reliability of diagnosing bacterial vaginosis is improved by a stan-dardized method of Gram stain interpretation. J Clin Microbiol. 1991;29:297-301.

Downloads

Published

2016-03-09

How to Cite

1.
Dyudyun AD, Polion NM. Microbiologic picture of microflora of female urogenital organs. Med. perspekt. [Internet]. 2016Mar.9 [cited 2024Nov.23];21(1):91-6. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/63491

Issue

Vol. 21 No. 1 (2016)

Section

CLINICAL MEDICINE

License

Copyright (c) 2017 Medical Perspectives

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.

Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.