Morphology of embryonic liver under the influence of silver and gold citrates on a background of lead intoxication.

Authors

  • V. I. Harets
  • V. F. Shatorna
  • Iu. O. Belska

DOI:

https://doi.org/10.26641/2307-0404.2016.2.71751

Keywords:

embryonic liver, lead acetate, silver citrate, gold citrate

Abstract

Morphological state of embryonic liver under the influence of silver and gold citrates on a background of lead intoxication was studied. We found that  values of the hepatofetal index in the groups Pb+Ag and Pb+Au had significant differences as compared to the group exposed to lead intoxication, but did not differ significantly from the control group and made up 0,086±0,001 and 0,083±0,001, respectively. Value of the relative area of blood vessels in groups Pb+Ag and Pb+Au was 13.08±0.53% and 16.83±0.53%, respectively, which had no significant difference as compared to control group, but differed from the value of lead intoxication group. Under the influence of silver citrate on a background of lead intoxication the relative area of hematopoietic cells was 52,5±0,95%; this indicates to modification action of silver on haematopoiesis. Thus, injection of silver and gold citrates prevents negative effect of lead on morphometric parameters of embryonic liver, relative area of blood vessels and hematopoietic cells. Experiment results showed protective effect of silver and gold citrates on a background of lead intoxication during hepatogenesis.

Author Biographies

V. I. Harets

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Medical Biology, Botany and Pharmacognosy
Sevastopols'ka str., 19, Dnipropetrovsk, 49027, Ukraine

V. F. Shatorna

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Medical Biology, Botany and Pharmacognosy
Sevastopols'ka str., 19, Dnipropetrovsk, 49027, Ukraine

Iu. O. Belska

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Medical Biology, Botany and Pharmacognosy
Sevastopols'ka str., 19, Dnipropetrovsk, 49027, Ukraine

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Published

2016-05-31

How to Cite

1.
Harets VI, Shatorna VF, Belska IO. Morphology of embryonic liver under the influence of silver and gold citrates on a background of lead intoxication. Med. perspekt. [Internet]. 2016May31 [cited 2024Nov.14];21(2):9-13. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/71751

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Section

THEORETICAL MEDICINE