Factors of cardiovascular risk and cognitive dysfunction in patients with controlled hypertension.

Authors

  • V. Yu. Krotova

DOI:

https://doi.org/10.26641/2307-0404.2016.2.72132

Keywords:

hypertension, risk factors, cognitive dysfunction

Abstract

According to the survey of 68 patients with arterial hypertension stage II, 1-2 degrees, controlled on the background of antihypertensive therapy, cardiovascular risk, severity of cognitive impairment were analyzed. Instrumental examination of ambulatory blood pressure monitoring; electrocardiography, ultrasound investigation of the main arteries of the head and neck was performed. Neuropsychological examination: an integrated assessment of cognitive functions by MMSE scale; memory evaluation using the procedure of memorizing "Saving 10 words" by Luria; rating of attention and speed of sensorimotor reactions by Schulte and Rybakov procedure was made. Total cardiovascular risk was defined on a scale «SCORE». Typical cognitive disorders in patients with hypertension of working age, even in the controlled blood pressure level were found. Presence of verbal memory disorders associated with hypertension was revealed. The importance of determining the overall cardiovascular risk, diagnosis of cognitive impairment and measuring thickness of the intima-media of the arterial wall as factors of brain lesion which is the target organ in arterial hypertension of 1-2 degrees, was proved.

Author Biography

V. Yu. Krotova

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Propedeutics of Internal Medicine
Dzerzhinsky str., 9, Dnepropetrovsk, 49044, Ukraine

References

Bylchenko AV. [Сognitive disorders and de-mentia in patients with hypertension]. Ukr. med. cha-sopys. 2014;6(104):71–75. Russian.

Kovalenko VN. [Stress and cardiovascular diseases]. 2015;355. Ukrainian.

Osipov EV. [Study Сognitive disorders in patients with hypertension]. Sovr. problemy nauki i obrazovanija. 2015;8(2):254-258. Russian.

Fang MC. Trends in Stroke Rates, Risk, and Out-comes in the United States, 1988-2008. Am. J. Med.; 2014.

Faraco G. Hypertension: a harbinger of stroke and dementia. J. Hypertens. 2013;62(5):810–817.

Justin BN. Heart disease as a risk factor for dementia. Clin. Epdemiol. 2013;5:135–145.

Nagai M. Hypertension and dementia. Am. J. Hypertens. 2010;23(2):116–124.

Skoog I. Effect of baseline cognitive function and antihypertensive treatment on cognitive and cardio-vascular outcomes: Study on cognition and prognosis in the elderly (SCOPE). Am. J. Hypertens. 2005;18.

Torre JC. Cerebral hemodynamics and vascular risk factor: setting the stage for cognitive disease. J. Alzheimers. Dis. 2012;32(3):553–67.

Wardlaw G, Smith C. Mechanism of sporadic cerebral small vessel disease:insight from neuroimaging. Lancet Neurol. 2013;12(5):483–497.

Downloads

Published

2016-05-31

How to Cite

1.
Krotova VY. Factors of cardiovascular risk and cognitive dysfunction in patients with controlled hypertension. Med. perspekt. [Internet]. 2016May31 [cited 2024Apr.20];21(2):47-52. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/72132

Issue

Section

CLINICAL MEDICINE