Disorders of cardiac hemodynamic in attack period of bronchial asthma in children.

Authors

  • V. А. Kondratiev
  • А. V. Reznyk

DOI:

https://doi.org/10.26641/2307-0404.2016.2.72152

Keywords:

children, cardiovascular system, hemodynamic, bronchial asthma

Abstract

Bydopplerechocardiographymethodtherewasstudiedfunctionalstateofcardiacventriclesandcharacterofhemodynamicdisordersin 48 patients aged 5-17 years in attack period of moderately-severe and severe bronchial asthma. Group of comparison included 40 healthy peers. Disordersofcentralandperipheralhemodynamicinattackperiodofbronchialasthmainchildrenwereaccompaniedbothbysystolicanddiastolicdysfunctionoftheleftandrightheartventricles, herewith right ventricle was functioning in the mode of hyperdynamic, and left one – in the mode of hypodynamic. Combinedsystolic-diastolicvariantofdysfunctionbothofrightandleftventricleswasdevelopingin 58,3% of patients with moderately-severe and in 91,6% of patients with severe bronchial asthma. Intheattackperiodofbronchialasthmainchildrenequaldirectionalityofsystolicanddiastolicdysfunctionofheartventricleswasdeveloping; this was characterized by synchronization of their function.Assessmentoffunctionalinteractionoftheventriclesunderconditionsofsevereasthmaattackshoweddirectandhigh (r=0,67) correlativeinteractionbetweenfindingofTeiindexoftheleftandrightventricles, whichcharacterizetheirsystolicfunction; this, under conditions of increased hemodynamic pre-loading testified to compensatory  increase of systolic interaction of ventricles. Direct and high (r=0,69) correlativeinteractionbetween time indices of isovolumic relaxation of the left and right ventricles, characterizing their diastolic function, testified to compensatory increase of diastolic interaction of ventricles under conditions of increase of hemodynamic post-loading.  Imbalance of central and peripheral link of hemodynamic in attack period ofbronchialasthmainchildrentestified to development of cardiac insufficiency, which was compensated predominantly at the expense of increase of heart contractions rate. 

Author Biographies

V. А. Kondratiev

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of pediatrics 2
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

А. V. Reznyk

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of pediatrics 2
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

References

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Published

2016-05-31

How to Cite

1.
Kondratiev VА, Reznyk АV. Disorders of cardiac hemodynamic in attack period of bronchial asthma in children. Med. perspekt. [Internet]. 2016May31 [cited 2024May18];21(2):57-62. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/72152

Issue

Section

CLINICAL MEDICINE