Preclinical study of the properties of human autosymbionts A. Viridans.

Authors

  • D. O. Stepanskyi
  • G. M. Kremenchutskyi
  • I. P. Koshova

DOI:

https://doi.org/10.26641/2307-0404.2016.2.72163

Keywords:

probiotics, preclinical study, aerococcus

Abstract

The paper presents data of preclinical study of autocamiones A. viridans properties. Acute toxicity and harmlessness of strains was tested. Strains of bacteria of Aerococcus genus were checked for absence of contamination by morphological, cultural, biochemical and tinctorial properties. Aerococci accumulate weight well on standard nutrient media, morphology, tinctorial and biochemical properties meet the standards. All indicators of activity of glutathione peroxidase, superoxide radical, superoxide, SOD, protein content comply with the standards. Antagonistic activity of the studied strains of aurococcus was investigated by the method of deferred antagonism to test cultures. Data show a high antagonistic activity of aurococcus strains to conditionally pathogenic microorganisms. During determination of acute toxicity of aurococcus in the observation period, edema and tissue necrosis at the injection site of aurococcus, death of mice was not marked were not revealed.A complete harmlessness of microbial suspension of aurococcus when administered to white mice per os was revealed.

Author Biographies

D. O. Stepanskyi

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Microbiology, virology, immunology and epidemiology
Soborna Sq., 4, Dnipropetrovsk, 49000, Ukraine

G. M. Kremenchutskyi

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Microbiology, virology, immunology and epidemiology
Soborna Sq., 4, Dnipropetrovsk, 49000, Ukraine

I. P. Koshova

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Microbiology, virology, immunology and epidemiology
Soborna Sq., 4, Dnipropetrovsk, 49000, Ukraine

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Published

2016-05-31

How to Cite

1.
Stepanskyi DO, Kremenchutskyi GM, Koshova IP. Preclinical study of the properties of human autosymbionts A. Viridans. Med. perspekt. [Internet]. 2016May31 [cited 2024May18];21(2):87-93. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/72163

Issue

Section

CLINICAL MEDICINE