Toxicological and hygienic regulation and assessment of danger of the new fungicide-cyflufenamid.

Authors

  • P. V. Stavnichenko
  • A. M. Antonenko
  • M. M. Korshun
  • V. G. Bardov

DOI:

https://doi.org/10.26641/2307-0404.2016.2.72279

Keywords:

cyflufenamid, fungicides, acceptable daily dose, toxicity, hazardous class

Abstract

Toxicodynamic peculiarities of the new fun­gicide – cyflufenamid were studied. It was found that in accordance with hygienic classification of pesticides, cyflufe­namid is referred to the 3rd class of hazard (moderately hazardous). It was shown that liver is the primary target organ of cyflufenamid action, thyroid gland, heart, kidneys, brain are secondary. It was established that cyflufenamid is mic­rosomal enzyme inducer. Acceptable daily dose of cyflufenamid for humans was substantiated on level of 0,01 mg/kg.

Author Biographies

P. V. Stavnichenko

Bogomolets National Medical University
Department of hygiene and ecology
T. Shevchenko boul., 13, Kyiv, 01601, Ukraine

A. M. Antonenko

Bogomolets National Medical University
Department of hygiene and ecology
T. Shevchenko boul., 13, Kyiv, 01601, Ukraine

M. M. Korshun

Bogomolets National Medical University
Department of hygiene and ecology
T. Shevchenko boul., 13, Kyiv, 01601, Ukraine

V. G. Bardov

Bogomolets National Medical University
Department of hygiene and ecology
T. Shevchenko boul., 13, Kyiv, 01601, Ukraine

References

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Published

2016-05-31

How to Cite

1.
Stavnichenko PV, Antonenko AM, Korshun MM, Bardov VG. Toxicological and hygienic regulation and assessment of danger of the new fungicide-cyflufenamid. Med. perspekt. [Internet]. 2016May31 [cited 2024May18];21(2):106-11. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/72279

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Section

PREVENTIVE MEDICINE