Modern aspects of atibiotic sensitivity of prominent pathogens of infectious complications.

Authors

  • O. A. Nazarchuk
  • N. I. Osadchuk
  • D. V. Palij

DOI:

https://doi.org/10.26641/2307-0404.2016.2.72282

Keywords:

infectious complications, antibiotics, sensitivity, burns

Abstract

In the research antibiotic sensitivity of opportunistic pathogens was studied. In 2011-2015 from 405 patients with burns there were isolated clinical strains of S. aureus (n 130), P. aeruginosa (n 127), A. baumannii (n 176), being the prominent pathogens of infectious complications. Clinical strains of S. aureus, P. aeruginosa, A. baumannii obtained all morphological, tentorial, cultural and biochemical qualities, typical for these species of bacteria. On the basis of the received results there wascarried out approximation and interpolation of these data, dynamic prognostic indexes of changes in S. aureus, P. aeruginosa, A. baumannii antibiotic sensitivity were obtained. Low sensitivity to ampicillini/sulbactam (58,63±8,58%), ceftriaxone (55,75±14,24%), gentamicin (57,92±10,76%), tobramycin (64,67±10,3%)  in clinical strains of S. аureus was proved. Prognostic optimizations of S. аureus sensitivity to amoxicillini/clavulanat (82,35%), gatifloxacin (94,12%) were determined. Clinical strains of P. aeruginosa, A. baumannii were shown to have low sensitivity to ceftazidime, cefoperazone, cefoperazone/sulbactam(20,08±2,98%; 48,88±6,49%, respectively). Progressive decrease of sensitivity to amikacin in P. aeruginosa (29,77±7,55%), A. baumannii (17,0±1,34 %) and to gatifloxacin in P. aeruginosa (28,53±1,35%), isolated from patients with burns were determined.

Author Biographies

O. A. Nazarchuk

Vinnytsa N.I. Pyrogov Memorial National Medical University MH of Ukraine
Pyrogov Str., 56, Vinnytsya, 21018, Ukraine

N. I. Osadchuk

Vinnytsa N.I. Pyrogov Memorial National Medical University MH of Ukraine
Pyrogov Str., 56, Vinnytsya, 21018, Ukraine

D. V. Palij

Vinnytsa N.I. Pyrogov Memorial National Medical University MH of Ukraine
Pyrogov Str., 56, Vinnytsya, 21018, Ukraine

References

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Paliy G, Nazarchuk O, Osadchuk N, Paliy D, Ko-valenko I. Prognostic criteria of sensitivity to antibiotics of Staphylococcus clinical strains J Education, Health and Sport (formerly Journal of Health Sciences). 2015;5(7):26-33.

Rice LB. The clinical consequences of antimicro-bial resistance. Current Opinion in Microbiology. 2009;12(5):476-81.

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Published

2016-05-31

How to Cite

1.
Nazarchuk OA, Osadchuk NI, Palij DV. Modern aspects of atibiotic sensitivity of prominent pathogens of infectious complications. Med. perspekt. [Internet]. 2016May31 [cited 2024May18];21(2):111-6. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/72282

Issue

Section

PREVENTIVE MEDICINE