State of free-radical peroxidation processes in rats with acute blood loss

Authors

  • Сніжана Сергіївна Чернадчук Odessa I. I. Mechnikov National University st. Dvoryanskaya, 2,. Odessa, Ukraine, 65000, Ukraine
  • Алія Октай Гизи Рустамова Odessa I. I. Mechnikov National University st. Dvoryanskaya, 2,. Odessa, Ukraine, 65000, Ukraine
  • Олександр Костянтинович Будняк Odessa I. I. Mechnikov National University st. Dvoryanskaya, 2,. Odessa, Ukraine, 65000, Ukraine
  • Сергій Анатолійович Петров Odessa I. I. Mechnikov National University st. Dvoryanskaya, 2,. Odessa, Ukraine, 65000, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2015.41500

Keywords:

lipid peroxidation, antioxidant system, acute blood loss

Abstract

A study of lipid peroxidation parameters and antioxidant systems in different tissues of rats with acute blood loss is conducted. As a result, it has been found that lipid peroxidation products increase in conditions of blood loss against the background of decreased activity of antioxidant enzymes in all investigated organs of rats

Author Biographies

Сніжана Сергіївна Чернадчук, Odessa I. I. Mechnikov National University st. Dvoryanskaya, 2,. Odessa, Ukraine, 65000

Candidate of Biological Sciences, Associate Professor

Department of Biochemistry

Алія Октай Гизи Рустамова, Odessa I. I. Mechnikov National University st. Dvoryanskaya, 2,. Odessa, Ukraine, 65000

Department of Biochemistry

Олександр Костянтинович Будняк, Odessa I. I. Mechnikov National University st. Dvoryanskaya, 2,. Odessa, Ukraine, 65000

Candidate of Biological Sciences, Associate Professor

Department of Biochemistry

Сергій Анатолійович Петров, Odessa I. I. Mechnikov National University st. Dvoryanskaya, 2,. Odessa, Ukraine, 65000

Doctor of Biological Sciences, Professor

Department of Biochemistry

References

Kurtoglu, E. (2003). Effect of iron supplementation on oxidative stress and antioxidant status in iron deficiency anemia. Biological Trace Element Research, 96 (1-3), 117–124. doi: 10.1385/bter:96:1-3:117

Kenya, M. P., Lukas, A. I., Guscov, E. P. (1993). Nyzkomolekulyarnіе antioxidant role in oxidative stress [The role of low molecular weight antioxidants in oxidative stress]. Successes Modern biology, 113 (4), 456–468.

Bulgakov, E. B. (2004). Perekysnoe oxidation lypydov membranes [Lipid peroxidation of membranes]. Successes chemistry, 54, 1540–1558.

Vladimirov, Y. A. (2000). Svobodny radicals in biology systems [Free radicals in biological systems]. Soros Educational Journal, 12, 13–19.

Voscresensciy, O. N. (2003) Peroxide lypydov in zhyvom organism [Lipid peroxides in vivo ]. Problems. med. chemistry, 16 (6), 563–583.

Osipov, A. N., Azizova, A. A., Vladimirov, Y. A. (2003). Active forms of oxygen and ih role in the body [Reactive oxygen species and their role in the body]. Modern successes. Biology, 31, 180–208.

Petrovich, Y. A. (2005). Svobodnoradykalnoe oxidation & its role in the pathogenesis of inflammation, and stress yshemyy [Free radical oxidation and its role in the pathogenesis of inflammation, ischemia and stress ]. Pathology. fyzyol. and ekperim. Therapy, 5, 85–92.

Vladimirov, Y. A. (2001). Svobodny radicals and antyoksydanti [Free radicals and antioxidants]. Journal of Medical Sciences, 8, 43–51.

Tymochko, M. F., Kobylska, L. I. (2002). Vilnoradicalni reactions and their metabolic role [Free radical reactions and their metabolic role]. Med. Chemistry, 1 (1), 19–24.

Abiaka, C., Al-Awadi, F., Olusi, S. (2003). Effect of Prolonged Storage on the Activities of Superoxide Dismutase, Glutathione Reductase, and Glutathione Peroxidase. Clinical Chemistry, 46 (4), 560–576.

Tyunov, L. A. (1995). Mechanisms estestvennoy detoxification and antioxidant protection [Mechanisms of natural detoxification and antioxidant protection]. Vestn. RAMS, 3, 9–13.

Official Journal of the European Union L276/33. Directive 2010/63 / EU of the European parliament and of the council of 22 September 2010 on the protection of animals used for scientific purposes. 86/609 / EC.20.10.2010.

Horyachkovskіy, A. G. (1998). Clinical biochemistry [Clinical biochemistry]. Odessa: Astroprint, 572.

Vyshtakalyuk, A. B. (2008). Protyvoanemycheskaya activity Polymetal International pectin complexes polisaharidov with Fe2+, Co2+, Cu2+ at razlychnom sootnoshenyy d-metals [Protivoanemicheskim activity polymetal pectic polysaccharides complexes with Fe2+, Co2+, Cu2+ at various ratios of d-metals]. Chemical and Pharmaceutical Journal, 42 (6), 3–6.

Downloads

Published

2015-04-24

Issue

Vol. 4 No. 1 (9) (2015)

Section

Biological sciences

License

Copyright (c) 2015 Сніжана Сергіївна Чернадчук, Алія Октай Гизи Рустамова, Олександр Костянтинович Будняк, Сергій Анатолійович Петров

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.

Authors, who are published in this journal, agree to the following conditions:

1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.

 2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.