Special features of the cardiac remodeling in patients with the different clinical forms of non-valvular atrial fibrillation
DOI:
https://doi.org/10.15587/2313-8416.2016.67673Keywords:
arterial fibrillation, progressing of disease, risk factors, cardiac remodeling, diastolic functionAbstract
According to the population studies the prevalence of atrial fibrillation (AF) is near 2 %, increases to the 9 % in persons older than 80 years. The character of structural-functional cardiac remodeling in patients with the different forms of AF is insufficiently studied for today.
Aim of research – to study the special features of the structural-functional cardiac remodeling in patients with the different forms of the non-valvular arterial fibrillation.
Materials and methods. There were examined 80 patients with AF (46 men and 34 women) 36–85 years old (the mean age 63,36±1,1 years). According to the aim of research all patients were divided into three groups depending on the clinical form of AF (paroxysmal, persistent and permanent). All patients underwent the standard general clinic examination, electrocardiography, echocardiography.
Results. In patients with paroxysmal form of AF took place the clinically less apparent heart failure comparing with persistent and permanent ones. Structural-functional state of myocardium at the permanent form of AF was characterized with the increase of left and right atrium diameter, left atrium volume index, left ventricle final-diastolic volume, systolic pressure in the pulmonary artery comparing with the paroxysmal and persistent ones. In the group with permanent form of AF in 71,43 % was detected the eccentric hypertrophy of the left ventricle.
Conclusion. Progressing clinical course from the paroxysmal to the permanent atrial fibrillation is characterized with the decrease of tolerance to the physical load, increase of the body mass index, left and right atrium diameter, predominance of prognostically unfavorable types of remodeling
References
Dyadyk, A. I., Bagrij, A. Eh., Holopov, L. S., Prikolota, O. A. (2012) Simpozium № 70. Fibrillyaciya predserdij. Novosti mediciny i farmacii, 9, 24–29.
Asotsiatsiia kardiologiv Ukrainy (2014). Diahnostyka ta likuvannia fibryliatsii peredserd. Rekomendatsii robochoi hrupy po porushenniam certsevoho rytmu. Kyiv, 167.
January, C. T., Wann, L. S., Alpert, J. S., Calkins, H., Cigarroa, J. E., Cleveland, J. C. et. al (2014). 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. Circulation, 130 (23), 2071–2104. doi: 10.1161/cir.0000000000000040
Zholbaeva, A. Z., Tabina, A. E., Goluhova, E. Z. (2015). Molekulyarnye mekhanizmy fibrillyacii predserdij: v poiske «ideal'nogo» markera. Kreativnaya kardiologiya, 2, 40–53.
Gupta, D. K., Shah, A. M., Giugliano, R. P., Ruff, C. T., Antman, E. M., Grip, L. T. et. al (2013). Left atrial structure and function in atrial fibrillation: ENGAGE AF-TIMI 48. European Heart Journal, 35 (22), 1457–1465. doi: 10.1093/eurheartj/eht500
Ishemichna hvoroba sercja: stabil'na stenokardija naprugy (2012). Praktykujuchyj likar, 1, 84–89.
Arterial'na gipertenzija. Onovlena ta adaptovana klinichna nastanova, zasnovana na dokazah (2012). Kyiv, 139.
Stewart, S. (2001). Population prevalence, incidence, and predictors of atrial fibrillation in the Renfrew/Paisley study. Heart, 86 (5), 516–521. doi: 10.1136/heart.86.5.516
Go, A. S., Hylek, E. M., Phillips, K. A., Chang, Y., Henault, L. E., Selby, J. V., Singer, D. E. (2001). Prevalence of Diagnosed Atrial Fibrillation in Adults. JAMA, 285 (18), 2370. doi: 10.1001/jama.285.18.2370
Lloyd-Jones, D. M. (2004). Lifetime Risk for Development of Atrial Fibrillation: The Framingham Heart Study. Circulation, 110 (9), 1042–1046. doi: 10.1161/01.cir.0000140263.20897.42
Drapkina, O. M., Kostiukevich, M. V. (2010). Arterial'naya gipertenziya: ot fibrillyacii predserdij i insul'ta do metabolicheskogo sindroma. Spravochnik poliklinicheskogo vracha, 8, 18–21.
Chiang, C.-E., Naditch-Brule, L., Murin, J., Goethals, M., Inoue, H., O’Neill, J. et. al (2012). Distribution and Risk Profile of Paroxysmal, Persistent, and Permanent Atrial Fibrillation in Routine Clinical Practice: Insight From the Real-Life Global Survey Evaluating Patients With Atrial Fibrillation International Registry. Circulation: Arrhythmia and Electrophysiology, 5 (4), 632–639. doi: 10.1161/circep.112.970749
Camm, A. J., Breithardt, G., Crijns, H., Dorian, P., Kowey, P., Le Heuzey, J.-Y. et. al (2011). Real-Life Observations of Clinical Outcomes With Rhythm- and Rate-Control Therapies for Atrial Fibrillation. Journal of the American College of Cardiology, 58 (5), 493–501. doi: 10.1016/j.jacc.2011.03.034
Fuchs, T., Baron, E. L., Leitman, M., Burgsdorf, O., Torjman, A., Vered, Z. (2012). Does Chronic Atrial Fibrillation Induce Cardiac Remodeling? Echocardiography, 30 (2), 140–146. doi: 10.1111/echo.12003
Akkaya, M. (2014). The degree of left atrial structural remodeling impacts left ventricular ejection fraction in patients with atrial fibrillation. Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology, 42 (1), 11–19. doi: 10.5543/tkda.2014.20726
Apostolakis, S., Sullivan, R. M., Olshansky, B., Lip, G. Y. H. (2014). Left ventricular geometry and outcomes in patients with atrial fibrillation: The AFFIRM Trial. International Journal of Cardiology, 170 (3), 303–308. doi: 10.1016/j.ijcard.2013.11.002
Shah, N., Badheka, A. O., Grover, P. M., Patel, N. J., Chothani, A., Mehta, K. et. al (2014). Influence of left ventricular remodeling on atrial fibrillation recurrence and cardiovascular hospitalizations in patients undergoing rhythm-control therapy. International Journal of Cardiology, 174 (2), 288–292. doi: 10.1016/j.ijcard.2014.04.011
Maslova, A. P. (2011). Remodelirovanie levogo zheludochka i perenosimost' fizicheskih nagruzok u bol'nyh s hronicheskoj serdechnoj nedostatochnost'yu i postoyannoj formoj fibrillyacii predserdij. Vestnik Orenburgskoj gosudarstvennoj medicinskoj akademii, 16, 312–314.
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Copyright (c) 2016 Виктор Денисович Сыволап, Дмитрий Андреевич Лашкул, Валерия Васильевна Марченко
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