Myocardium remodeling features in patients with coronary heart disease comorbid with non-alcoholic fatty liver disease

Authors

  • Наталія Сергіївна Михайловська Zaporizhzhia State Medical University 26 Mayakovskogo ave., Zaporizhzhya, Ukraine, 69035, Ukraine
  • Любов Євгеніївна Міняйленко Zaporizhzhia State Medical University 26 Mayakovskogo ave., Zaporizhzhya, Ukraine, 69035, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2016.60797

Keywords:

coronary heart disease, non-alcoholic fatty liver disease, remodeling, systolic and diastolic function

Abstract

The aim of research is to assess the special features of heart remodeling, myocardium systolic and diastolic functions in patients with coronary heart disease comorbid with non-alcoholic fatty liver disease.

Methods: the cross analytical research included 33 patients with coronary heart disease among them 18 patients with concomitant non-alcoholic fatty liver disease. All patients underwent the general clinical and laboratory examination, anthropometric measurements. The two-dimensional echocardiography and impulsive and wave dopplerography was carried out using "SonoAce" 8000SE scanner of «Medison» Company (Korea) with the help of conventional methods according to recommendations of American echocardiography society and European echocardiography association (2005).

Results: Among patients with coronary heart disease comorbid with non-alcoholic fatty liver disease were observed the structural and functional changes of heart such as concentric hypertrophy. In the group with non-alcoholic fatty heart disease the frequency of systolic and diastolic dysfunction was higher. In patients with coronary heart disease comorbid with non-alcoholic fatty liver disease were revealed correlative interconnections between indicators of structural and functional reconstruction of the left ventricle and functional samples of the liver and also with components of metabolic syndrome. These correlations indicate the pathogenetic connection between the found disorders

Author Biographies

Наталія Сергіївна Михайловська, Zaporizhzhia State Medical University 26 Mayakovskogo ave., Zaporizhzhya, Ukraine, 69035

MD, Professor, Head of the Department

Department of General practice – family medicine 

Любов Євгеніївна Міняйленко, Zaporizhzhia State Medical University 26 Mayakovskogo ave., Zaporizhzhya, Ukraine, 69035

Department of general practice – family medicine

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Published

2016-02-28

Issue

Section

Medical