Application of cytogenetic researches in efficiency assessment of vaccines against leukemia virus in cattle
DOI:
https://doi.org/10.15587/2313-8416.2018.121096Słowa kluczowe:
genetic monitoring, cattle leukemia virus, immunogenesis, mice, bone marrow cellsAbstrakt
We studied the effect of immunogens of the leukemia virus in cattle on the cytogenetic parameters of bone marrow in the dynamics of immunogenesis. We found that each drug has its own specific effect, which is due to the structural differences of the leukemia virus in cattle. The method of cytogenetic studies of bone marrow cells should be used to assess the safety and immunogenic properties of retroviral origin drugs
Bibliografia
Fedorova, N. E., Medzhidova, А. А., Medzhidova, М. G., Kusch, А. А. (2003). Blok kletochnoy proliferatsii i patologii mitoza v kletkakh infitsirovannykh tsitomegalovirusom [Cell proliferation blocking and mitosis pathology in cells infected by cytomegalovirus]. Academy of science abstracts, 392 (4), 552–555.
Cerkhezia, S. E., Mykhaylova, G. R., Gorshunova, L. P. (1980). Issledovaniye khromosom v kletkakh kostnogo mozga myshey. immunizirovannykh antirabicheskimi vaktsinami [Chromosome research of bone marrow cells of mice which took anti rabies vaccine]. Cytology and genetics, 14 (4), 67–70.
Il’inskykh, I. N., Novitsky, V. V., Il’inskykh, E. N., Il’inskykh, N. N., Tkachenk, S. B. (2005). Infektsionnaya kariopatologiya [Infectious caryopathology]. Tomsk: Tomsk university press, 168.
Yarylin, А. А. (2003). Apoptoz i ego rol v tselostnom organizme [Apoptosis and its role in an organism as a whole]. Glaucoma, 2, 46–54.
Serenot, Ch. K. (2005). Izucheniye izmeneniy morfologii yadra kultury kletok k 562 pod vozdeystviyem vaktsin virusov [Studies related to morphological changes k-562 cell culture nuclei influenced by viral vaccine]. Thesis collection related to the topics of 64-th International scientific students’ conference named after N. I. Pirogov, 52.
Sivakova, T. N., Mylnikova, E. A. (2010). Kariopaticheskoye deystviye vaktsiny Nobivak Rabies na kletki kostnogo mozga i semennikov belykh myshey [Caryopathic effect of Nobivak Rabies vaccine on bone marrow cells and white mice testis]. Fundamental medical-biological science and practical healthcare, 46–49.
Yakovlev, A. F., Stefanova, V. N., Rossoha, V. I., Yefimenko, L. I. (1990). Metodicheskiye rekomendatsii po tsitogeneticheskomu testirovaniyu v svinovodstve [Methodological guidance on cytogenetic testing in swine breeding]. Kharkiv: Ukraine Veterinary Theoretical research institute, 24.
Brodbeck, W. G., Shive, M. S., Colton, E., Ziats, N. P., Anderson, J. M. (2002). Interleukin-4 inhibits tumor necrosis factor-α–induced and spontaneous apoptosis of biomaterial-adherent macrophages. Journal of Laboratory and Clinical Medicine, 139 (2), 90–100. doi: 10.1067/mlc.2002.121260
Saito, T., Kuss, I., Dworacki, G., Gooding, W., Johnson, J. T., Whiteside, T. L. (1999). Spontanous ex vivo apoptosis of peripheral blood mononuclear cells in patients with head and neck cancer. Clinical Cancer Research, 5, 1263–1273.
Il’inskykh, N. N. (1984). Tsitogenenticheskiy analіz posledstviy infektsionnogo mutageneza v svyati s sostoyaniyem immunoreaktivnosti organizma [Cytogenetic analysis of consequences of infectious mutagenesis complimented by condition of immunoreactivity of an organism]. Tomsk, 42.
Ingel, F. I. (2006). Perspectives of micronuclear test in human lymphocytes cultivated in cytogenetic block conditions. Part 1: Cell proliferation. Ecological Genetics, 4 (3), 7–19. doi: 10.17816/ecogen437-19
Ilin, D. A. (2006). Aspekty formirovaniya mikroyader [Formation of micronuclei]. Natural science and humanism, 3 (3), 58.
Yarylin, А. А. (1996). Apoptoz i ego mesto v immunnykh protsessakh [Apoptosis and its role in immune processes]. Immunology, 6, 10–23.
Shimizu, N., Kamezaki, F., Shigematsu, Sh. (2005). Tracking of microinjected DNA in live cells reveals the intracellular behavior and elimination of extrachromosomal genetic material. Nucleic Acids Research, 33 (19), 6296–6307. doi: 10.1093/nar/gki946
##submission.downloads##
Opublikowane
Numer
Dział
Licencja
Copyright (c) 2018 Maria Drahulian, Tetiana Dorosch, Svitlana Kostenko
Utwór dostępny jest na licencji Creative Commons Uznanie autorstwa 4.0 Międzynarodowe.
Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.
Authors, who are published in this journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
