Application of cytogenetic researches in efficiency assessment of vaccines against leukemia virus in cattle

Авторы

  • Maria Drahulian Национальный университет биоресурсов и природопользования Украины ул. Героев обороны, 15, г. Киев, Украина, 03041, Ukraine https://orcid.org/0000-0003-1512-0104
  • Tetiana Dorosch Национальный университет биоресурсов и природопользования Украины ул. Героев обороны, 15, г. Киев, Украина, 03041, Ukraine https://orcid.org/0000-0002-5430-3782
  • Svitlana Kostenko Национальный университет биоресурсов и природопользования Украины ул. Героев обороны, 15, г. Киев, Украина, 03041, Ukraine https://orcid.org/0000-0002-7816-3374

DOI:

https://doi.org/10.15587/2313-8416.2018.121096

Ключевые слова:

genetic monitoring, cattle leukemia virus, immunogenesis, mice, bone marrow cells

Аннотация

We studied the effect of immunogens of the leukemia virus in cattle on the cytogenetic parameters of bone marrow in the dynamics of immunogenesis. We found that each drug has its own specific effect, which is due to the structural differences of the leukemia virus in cattle. The method of cytogenetic studies of bone marrow cells should be used to assess the safety and immunogenic properties of retroviral origin drugs

Биографии авторов

Maria Drahulian, Национальный университет биоресурсов и природопользования Украины ул. Героев обороны, 15, г. Киев, Украина, 03041

Кандидат биологических наук, научный сотрудник

Кафедрa генетики, разведения и биотехнологии животных

Tetiana Dorosch, Национальный университет биоресурсов и природопользования Украины ул. Героев обороны, 15, г. Киев, Украина, 03041

Кандидат ветеринарных наук, ассистент

Кафедра терапии и клинической диагностики

Svitlana Kostenko, Национальный университет биоресурсов и природопользования Украины ул. Героев обороны, 15, г. Киев, Украина, 03041

Доктор биологических наук, профессор

Кафедра генетики, разведения и биотехнологии животных

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Опубликован

2018-01-16

Выпуск

Раздел

Ветеринарные науки