Определение токсичности нитратов с использованием цитоморфологических параметров разных тканей рыб как биомаркера
DOI:
https://doi.org/10.15587/2313-8416.2015.49341Słowa kluczowe:
питьевая вода, нитраты, генотоксичность, цитотоксичность, лейкоцитарная формула крови рыбAbstrakt
Проведен биологический анализ водных образцов содержащие разные концентрации нитратов. Описывается влияние нитратов на организм и клетки рыб. Получены данные о негативном влиянии ПДК нитратов в воде. Показано, что при токсическом влиянии нитратов на организм рыб происходят изменения количественного состава лейкоцитов периферической крови, также отмечены структурные изменения ядер клеток в различных тканях. Обнаружено, что нитраты, содержащиеся в пробах воды, имеют цитогенотоксический эффект
Bibliografia
Levich, A. P., Bulgakov, N. G., Maksimov, V. N. (2004). Theoretical and methodological foundations of regional technology control environment according to ecological monitoring. Moscow, 271.
Panichev, K. V., Serednyak, V. G., Karzhan, M. V. (2000). Intoxication metgemoglobinoobrazovatelyami poisoning in children. Anesthesiology. and reanimatol, 56–58.
Gupta, S. K., Gupta, R. C., Gupta, A. B., Seth, A. K., Bassin, J. K., Gupta, A. (2000). Recurrent Acute Respiratory Tract Infections in Areas With High Nitrate Concentrations in Drinking Water. Environmental Health Perspectives, 108 (4), 363–366. doi: 10.1289/ehp.00108363
Patika, V. P., Makarenko, N. A., Moklyachuk, L. I.; Patiki, V. P. (Ed.) (2005). Agroekologіchna otsіnka Welcome mіneralnih that pestitsidіv. Kyiv, 300.
Zhukov, G. F., Filin, S. A., Zaitsev, A. N., Mamonov, L. G. (1991). Of nitrate in the composition of the diet of young children. Nutrition, 6, 49–53.
Vergolyas, M. R., Kucherenko, T. V., Arhipchuk, V. V. (2007). Comparative Analysis of Incidence of cells with micronuclei and dual cores had carp Carassius auratus in natural and laboratory conditions. Dosyagnennya problems of genetics, selektsіi that bіotehnologіi. Kyiv, 1, 203–206.
Goncharuk, V. V., Vergolyas, M. P. (2009). Sposіb viznachennya tsitotoksichnostі Water seredovischa, Pat. 85,493 Ukraine: the IPC G 01N 33/18., the applicant and the patentee, Kiev, Institute of Colloid and Water Chemistry, National Academy of Sciences of Ukraine, 200801532; zayavl.06.02.08; publ. 26.01.09, Bul. 2, 4.
Norppa, H. (2003). What do human micronuclei contain? Mutagenesis, 18 (3), 221–233. doi: 10.1093/mutage/18.3.221
Vergoljas, M. R., Goncharuk, V. V. (2008). Vykorystannja cytologichnyh biomarkeriv na rybah dlja ocinky antropogennogo zabrudnennja mors'kyh i prisnyh vod. Faktory eksperymental'noi' evoljucii' organizmiv. Kyiv: LOGOS, 4, 60–63.
Goncharuk, V. V., Vergolyas, M. R., Boltіna, І. V. (2011). Sposіb viznachennya genotoksichnosti Water seredovischa. Pat. 95,717 Ukraine: the IPC G 01,33/18. VV,; the applicant and the patentee, Kiev, Institute of Colloid and Water Chemistry, National Academy of Sciences of Ukraine. 201004569; zayavl.19.04.10; publ. 25.08.11, Bul. 16, 3.
Arkhipchuk, V. V., Garanko, N. N. (2005). Using the nucleolar biomarker and the micronucleus test on in vivo fish fin cells. Ecotoxicology and Environmental Safety, 62 (1), 42–52. doi: 10.1016/j.ecoenv.2005.01.001
Hayashi, M., Ueda, T., Uyeno, K., Wada, K., Kinae, N., Saotome et. al (1998). Development of genotoxicity assay systems that use aquatic organisms. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 399 (2), 125–133. doi: 10.1016/s0027-5107(97)00251-0
Lakin, G. F. (1980). Biometrics. Moscow: Higher, 293.
Ivanova, N. T. (1983). Atlas blood cells of fish. Moscow: Light and food industries, 184.
Vergolyas, M. R., Bezrukov, V. F., Manilo L. G. (2007).Tsitologіchna characteristic periferichnoї krovі dev'yati vidіv RIB. Suchasnі problemi bіologії, ekologії that hіmії. Zaporizhya, 2, 217–220.
SanPyN 2.1.4.1175-02 «Gygyenycheskye trebovanyja k kachestvu vody necentralyzovannogo vodosnabzhenyja. Sanytarnaja ohrana ystochnykov» (2003). Canytarno-epydemyologycheskyepravyla y normatyvy. Moscow.
DSTU 7527 (2014). Water Pitney. Vimogi that methodological kontrolyuvannya of Quality. Enter 2014-02-01. Kyiv: DP UkrNDNC, 10.
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