Стан ремоделювання бронхів у хворих на бронхіальну астму школярів за поліморфізму генів сімейства Глютатіон-S-Трансфераз
DOI:
https://doi.org/10.15587/2313-8416.2016.59327Słowa kluczowe:
бронхіальна астма, ремоделювання бронхів, глутатіон-S- трансфераза, поліморфізм генів, школяріAbstrakt
Встановлено, що у хворих бронхіальною астмою школярів делеційний поліморфізм генів GSТT1 та GSТM1 у гомозиготному стані трапляється утричі рідше порівняно з пацієнтами із генотипом GSTT1+М1+ та більш, ніж удвічі підвищує ризик тяжкого перебігу захворювання. Доведено, що процеси ремоделінгу бронхів більш агресивні у хворих, які мають постійний контакт з тютюновим димом
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