Characteristics of the lipid profile in patients with morbid obesity before and after surgical treatment, depending on the type of surgical intervention.

R. V. Duka


Excessive deposition of adipose tissue in the body is often associated with dyslipidemic disorders and various risk factors for cardiovascular disease. The abdominal-visceral form is a serious predictor of cardiovascular mortality. The aim of the study was to establish the prevalence of lipid metabolism disorders in patients with morbid obesity and to evaluate the influence of surgical methods of treatment, namely biliopancreatic shunting in the Hess-Marceau modification and longitudinal gastrectomy in the postoperative period on the degree of correction of dyslipidemia in these patients. 57 patients (36 (63.2%) women and 21 (36.8%) men) with morbid obesity were in-depth examined, age from 21 to 62 years (mean age 40.0±1.38 years), who were under observation at the Department of Surgery N 1,SE "DMA". Significant violations of lipid metabolism in these patients were revealed, which significantly correlated with indicators of excessive body weight. There were established general trends towards a significant decrease (p <0.001) of body mass index and BMI in patients of both groups after 3 months from the start of treatment, which led to a significant improvement in lipid metabolism.


morbid obesity; surgical treatment; biliopancreatic shunting; longitudinal gastrectomy; lipid metabolism

Full Text:



Dedov II, Mel'nichenko GA. [Obesity. Etiology, pathogenesis, clinical aspects]. Moskva. 2004;456. Russian.

Dedov II. [Morbid obesity]. Moskva. 2014;608. Russian.

Rebrova OYu. [Statistical analysis of medical data. Application of software package STATISTICA]. Moskva. 2002;312. Russian.

Sedletskiy YuI. [Modern methods of treating obesi­ty. A guide for doctors]. Sankt-Peterburg. 2007;416. Russian.

Khat'kov IE, Gurchenkova EYu. [Endoscopic in­terventions in the treatment of alimentary-constitutional obesity]. Moskva. 2013;141. Russian.

Yashkov YuI. [About surgical methods of treat­ment of obesity]. Moskva. 2010;47. Russian.

Buchwald H, Avidor Y, Braunwald E, et al. Ba­riatric surgery: a systematic review and metaanalysis. JAMA. 2004;292:1724-37.

Freedman D, Ron E, Ballard-Barbash R, et al. Body mass index and all-cause mortality in a nationwide US cohort. Int. J. Obes (Lond.). 2006;30:822-9.

Sjostrom L, Narbo K, Sjostrom D, et al. Effects of bariatric surgery on mortality in Swedish Obese Subjects. N. Engl. J. Med. 2007;357:741-52.

Lenz M, Richter T, Muhlhauser I. The morbidity and mortality associated with overweight and obesity in adulthood: a systematic review. Dtsch. Arztebl. Int. 2009;106:641-48.

GOST Style Citations

  1. Дедов И.И. Ожирение. Этиология, патогенез, клинические аспекты / И.И. Дедов, Г.А. Мельниченко. – Москва, 2004. – 456 с.
  2. Дедов И.И. Морбидное ожирение / под ред. И.И. Дедова – Москва, 2014. – 608 с.
  3. Реброва О.Ю. Статистический анализ меди­цинских данных. Применение пакета прикладных программ STATISTICA / О.Ю. Реброва – Москва: МедиаСфера, 2002. – 312 с.
  4. Седлецкий Ю.И. Современные методы лече­ния ожирения. Руководство для врачей / Ю.И. Сед­лецкий. – СПб.: Элби-СПб, 2007. – 416 с.
  5. Хатьков И.Е. Эндоскопические вмешательства при лечении алиментарно-конституционального ожи­рения / И.Е. Хатьков, Е.Ю. Гурченкова. – Москва: Вита-Пресс, 2013. – 141 с.
  6. Яшков Ю.И. О хирургических методах лече­ния ожирения / Ю.И. Яшков – Москвва: АирАрт, 2010. – 47 с.
  7. Bariatric surgery: a systematic review and meta­analysis / H. Buchwald, Y. Avidor, E. Braunwald [et al.] // JAMA – 2004. – Vol. 292. – P. 1724-1737.
  8. Body mass index and all-cause mortality in a na­tionwide US cohort / D. Freedman, E. Ron, R. Ballard-Barbash [et al.] // Int. J. Obes. – 2006. – N 30. – P. 822-829.
  9. Effects of bariatric surgery on mortality in Swe­dish Obese Subjects / L. Sjostrom, K. Narbo, D. Sjostrom [et al.] // N. Engl. J. Med. – 2007. – Vol. 357. – P. 741-752.
  10. Lenz M. The morbidity and mortality associated with overweight and obesity in adulthood: a systematic review / M. Lenz, T. Richter, I. Muhlhauser // Dtsch. Arz­tebl. Int. – 2009. – Vol. 106. – P. 641-648.



  • There are currently no refbacks.