Characteristics of the lipid profile in patients with morbid obesity before and after surgical treatment, depending on the type of surgical intervention.
DOI:
https://doi.org/10.26641/2307-0404.2017.4.117678Keywords:
morbid obesity, surgical treatment, biliopancreatic shunting, longitudinal gastrectomy, lipid metabolismAbstract
Excessive deposition of adipose tissue in the body is often associated with dyslipidemic disorders and various risk factors for cardiovascular disease. The abdominal-visceral form is a serious predictor of cardiovascular mortality. The aim of the study was to establish the prevalence of lipid metabolism disorders in patients with morbid obesity and to evaluate the influence of surgical methods of treatment, namely biliopancreatic shunting in the Hess-Marceau modification and longitudinal gastrectomy in the postoperative period on the degree of correction of dyslipidemia in these patients. 57 patients (36 (63.2%) women and 21 (36.8%) men) with morbid obesity were in-depth examined, age from 21 to 62 years (mean age 40.0±1.38 years), who were under observation at the Department of Surgery N 1,SE "DMA". Significant violations of lipid metabolism in these patients were revealed, which significantly correlated with indicators of excessive body weight. There were established general trends towards a significant decrease (p <0.001) of body mass index and BMI in patients of both groups after 3 months from the start of treatment, which led to a significant improvement in lipid metabolism.
References
Dedov II, Mel'nichenko GA. [Obesity. Etiology, pathogenesis, clinical aspects]. Moskva. 2004;456. Russian.
Dedov II. [Morbid obesity]. Moskva. 2014;608. Russian.
Rebrova OYu. [Statistical analysis of medical data. Application of software package STATISTICA]. Moskva. 2002;312. Russian.
Sedletskiy YuI. [Modern methods of treating obesity. A guide for doctors]. Sankt-Peterburg. 2007;416. Russian.
Khat'kov IE, Gurchenkova EYu. [Endoscopic interventions in the treatment of alimentary-constitutional obesity]. Moskva. 2013;141. Russian.
Yashkov YuI. [About surgical methods of treatment of obesity]. Moskva. 2010;47. Russian.
Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and metaanalysis. JAMA. 2004;292:1724-37.
Freedman D, Ron E, Ballard-Barbash R, et al. Body mass index and all-cause mortality in a nationwide US cohort. Int. J. Obes (Lond.). 2006;30:822-9.
Sjostrom L, Narbo K, Sjostrom D, et al. Effects of bariatric surgery on mortality in Swedish Obese Subjects. N. Engl. J. Med. 2007;357:741-52.
Lenz M, Richter T, Muhlhauser I. The morbidity and mortality associated with overweight and obesity in adulthood: a systematic review. Dtsch. Arztebl. Int. 2009;106:641-48.
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