Influence of maternal infection on the morpho-functional state of preterm fetuses’ adrenal cortex

Authors

DOI:

https://doi.org/10.15587/2519-4798.2017.105328

Keywords:

adrenals, fetus, intrauterine infection, hypoxia, prematurity, stress, stillbirth, fetoplacental failure

Abstract

Adrenals as the one of main organs that reacts to a stress have the extreme importance for the normal organism development.  Despite numerous researches in the perinatal period, the problem of pregnancy infections on the morpho-functional state of adrenals of fetuses was not completely studied.

Methods. Organs were taken from incisions of premature fetuses (gestational age 24-36 weeks). The material was divided in 3 groups: control, chronic intrauterine hypoxia and infections. The study included two adrenals, investigated histologically and immunohistochemically.

Results. Mother’s infectious pathology has the more harmful effect on fetuses’ adrenals than a “pure chronic intrauterine hypoxia”. Іn fetuses was reveled a hypoplasia of glomerular zone. In all groups were observed nidi of cytolysis and spongyocytes resorption in the bundle zone with cortisol production increase. In a fetal cortex is observed the exhaustion of its functional activity.

Conclusions. These data testify to adaptive reactions of fetuses’ adrenals as a response to antigen stimulation

Author Biographies

Vira Tovazhnianska, Kharkiv National Medical University Nauky ave., 4, Kharkiv, Ukraine, 61022 Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176

Postgraduate student

Department of Pathological Anatomy

Assistant

Department of Pathological Anatomy 

Irina Sorokina, Kharkiv National Medical University Nauky ave., 4, Kharkiv, Ukraine, 61022

MD, Professor

Department of Pathological Anatomy

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Published

2017-06-30

How to Cite

Tovazhnianska, V., & Sorokina, I. (2017). Influence of maternal infection on the morpho-functional state of preterm fetuses’ adrenal cortex. ScienceRise: Medical Science, (6 (14), 28–32. https://doi.org/10.15587/2519-4798.2017.105328

Issue

No. 6 (14) (2017)

Section

Medical Science

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Copyright (c) 2017 Vira Tovazhnianska, Irina Sorokina

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