Peculiarities of clinical development of schizophrenia with comorbid somatic disorders.
Keywords:schizophrenia, cardiovascular diseases, diabetes mellitus of type II, obesity, clinical-psychopathological characteristics
In order to identify the clinical features of schizophrenia associated with somatic diseases, 186 patients with schizophrenia (50 patients with schizophrenia with cardiovascular diseases, 42 patients with schizophrenia with type 2 diabetes, 44 patients with schizophrenia with obesity and 50 patients with schizophrenia without chronic somatic diseases) were surveyed. Socio-demographic, clinical-dynamic and clinical-psychopathological features of schizophrenia (according to PANSS scale), connected with somatic diseases in a comparative aspect with patients with schizophrenia without somatic pathology were studied. It was found that somatic pathology combined with schizophrenia aggravates psychopathological symptoms, modifies clinical manifestations of schizophrenia and is associated with decrease in the level of social realization of patients, increase in the number of hospitalizations and a significant course of psychotic process. Among clinical features of schizophrenia with somatic disorders there was defined: in cardiovascular diseases - the presence of hallucinatory behavior, hypochondrial ideas and anxiety-depressive symptoms; in type 2 diabetes - hallucinatory activity in combination with excitement, impulsivity, hypochondrial ideas, depressive symptoms, and attention deficit, in obesity - the prevalence of negative symptoms over positive, expressed social rejection, depletion of social contacts and the presence of depressive experiences.
Kozlov AP. [Medical statistics: textbook]. Kharkov, XNU. 2006;88. Russian.
Mendelevich BD, Kuklina AM. [To the question of the prevalence of somatic pathology among patients suffering from mental disorders]. Kazanskiy meditsinskiy zhurnal. 2012;3:532-4. Russian.
Mosolov SN. [Scales of psychometric assessment of the symptoms of schizophrenia and the concept of positive and negative disorders]. M, Novuy tsvet. 2001;238. Russian.
Revenok OA, Marunkevich YY. [Features of concomitant somatic pathology in patients with paranoid schizophrenia]. Arxіv psikhіatrіi. 2014;4:75-79. Russian.
Semke AV, Mal`ceva YL. [Schizophrenia combined with somatic pathology: clinical, adaptive and rehabilitative aspects]. Sibirskiy vestnik psikhiatrii i narkologii. 2009;3:42-44. Russian.
Tyurkina TA. [Associated somatic diseases in patients with schizophrenia]. Sibirskiy vestnik psikhiatrii i narkologii. 2010;5:47-49. Russian.
Ringen PA, Engh JA, Birkenaes AB, et al. Increased Mortality in Schizophrenia Due to Cardiovascular Disease – A Non-Systematic Review of Epidemiology, Possible Causes, and Interventions. Front Psychiatry. 2014;5:137.
Meetoo D. Dangerous liaisons: The relationship between schizophrenia and diabetes. Journal of Diabetes Nursing. 2013;17:104-11.
Castle DJ, Buckley PF, Gaughran FP. Physical Health and Schizophrenia. Oxford University Press. 2017;136.
Tandon R. Medical comorbidities of schizophrenia. Digest of Psychiatry. 2013;3(42):55-51.
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