Clinical and psychopathological features of course and correction of depressive disorders in patients with brain tumors, prevention and rehabilitation
Keywords:brain tumors, mental and depressive disorders, experimental psychological research, psychotherapeutic correction, prevention, rehabilitation
The article studys the psychological characteristics in patients with brain tumors of different localization which allows to reduce the diagnostic period and, as a result, minimize the time of early detection and the consequences of the surgical treatment of this pathology, and to cause a positive effect on preventing the development of psychopathological disorders at the hospital stage. Analysis of the clinical manifestations of depressive disorders of the subclinical level revealed their polymorphism: depression was accompanied by various variants of asthenic (prevalence of dyssomnias, psychalgia, adynamia and anxiety component) and anxiety (prevalence of senestopathies, hypochondria, phobia) states. The revealed symptom complexes of psychopathological and pathopsychological characteristics of the patient's condition were the clinical justification for the choice of methods of psychotherapeutic correction. Adjuvant psychological therapy, individual rational and family psychotherapy were used as the basic method of psychotherapeutic influence. Pharmacological correction included: anxiolytics, antidepressants, atypical mild antipsychotics in low doses. The results of the SCL-90-R test demonstrate the effectiveness of the comprehensive treatment aimed at preventing and reducing the manifestations of psychopathological symptoms. Comparison of the mean values of the SCL-90-R test revealed significant differences in such indicators as somatization (p<0.05), depressiveness (p<0.01), anxiety (p<0.05); high statistical significance is noted in the “index of symptom severity” integral indicator (p<0.01). Obtained results of psychological and psychiatric research became the basis for the development of differential diagnostic criteria for the diagnosis and prevention of the development of mental disorders.
Udalov YuD, Gordiyenko AV, Samoylov AS, Zabelin MV, Bakharev SA. [Psychoemotional stress in so¬matically burdened patients with surgical oncology as one of the factors of postoperative complications]. Issledovaniya i praktika v meditsine. 2018;5(3):117-25. Rus¬sian. doi: https://doi.org/10.17709/2409-2231-2018-5-3-12
Sobchik LN. [Color selection method. Modification of the eight-color Luscher testї]. Sankt-Peterburh: Rech; 2015. Russian.
Solopova AG, Idrisova LE, Makatsariya AD, Chukanova EM. [Psychosomatic medicine: a key to effective rehabilitation in oncology patients]. Obstetrics, Gynecology and Reproduction. 2017;11(1):65-73. Russian.
Johnson KJ, Broholm H, Scheurer ME, Lau CC, Hainfellner JA, Wiemels J, Schwartzbaum J. Advancing brain tumor epidemiology – multi-level integration and international collaboration: The 2018 Brain Tumor Epideiology Consortium meeting report. Clin Neuropathol. 2018;37(6):254-61. doi: https://doi.org/10.5414/NP301148
Ostrom QT, Cioffi G, Gittleman H, Patil N, Waite K, Kruchko C, Barnholtz-Sloan JS. CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2012-2016. Neuro Oncol. 2019;21(Suppl 5):v1-v100. doi: https://doi.org/10.1093/neuonc/noz150
Chopra D, De La Garza R 2nd, Lacourt TE. Clinical relevance of a Body Image Scale cut point of 10 as an indicator of psychological distress in cancer patients: results from a psychiatric oncology clinic. Support Care Cancer. 2020;29:231-7. doi: https://doi.org/10.1007/s00520-020-05491-0
Assi HI, Hilal L, Abu-Gheida I, Berro J, Sukhon F, Skaf G, Geara F, Boulos F, Charafeddine M, Tabbarah A, Khoury J, Najjar M. Demographics and outco¬mes of meningioma patients treated at a tertiary care cen¬ter in the Middle East. Clin Neurol Neurosurg. 2020;195:105846. doi: https://doi.org/10.1016/j.clineuro.2020.105846
Lan B, Jiang S, Li T, Sun X, Ma F. Depression, anxiety, and their associated factors among Chinese early breast cancer in women under 35 years of age: A cross sectional study. Curr Probl Cancer. 2020;10:100558. doi: https://doi.org/10.1016/j.currproblcancer.2020.100558
Derogatis LR. SCL-90-R: Administration, Scoring of Procedures Manual-II for the R (evised) Version and Other Instruments of the Psychopathology Rating Scale Series: Clinical Psychometric Research Incorporated; 1992.
Diamond EL, Prigerson HG, Correa DC, Reiner A, Panageas K, Kryza-Lacombe M, Buthorn J, Neil EC, Miller AM, DeAngelis LM, Applebaum AJ. Prognostic awareness, prognostic communication, and cognitive function in patients with malignant glioma. Neuro Oncol. 2017;19(11):1532-41. doi: https://doi.org/10.1093/neuonc/nox117
Rajeshwari A, Revathi R, Prasad N, Michelle N. Assessment of Distress among Patients and Primary Caregivers: Findings from a Chemotherapy Outpatient Unit. Indian J Palliat Care. 2020;26(1):42-46. doi: https://doi.org/10.4103/IJPC.IJPC_163_19
R Core Team. R: A Language and Environment for Statistical Computing [Internet]. Vienna, Austria: R Foundation for Statistical Computing; 2020. Available from: https://www.R-project.org/
Dong M, Cioffi G, Wang J, Waite KA, Ostrom QT, Kruchko C, Lathia JD, Berens ME, Connor J, Barnholtz-Sloan JS. Sex differences in cancer incidence and survival: a pan-cancer analysis. Cancer Epidemiol Biomarkers Prev. 2020;29(7):1389-97. doi: https://doi.org/10.1158/1055-9965.EPI-20-0036
Wang R, Zhu Y, Liu X, Liao X, He J, Niu L. The Clinicopathological features and survival outcomes of patients with different metastatic sites in stage IV breast cancer. BMC Cancer. 2019;19(1):1091. doi: https://doi.org/10.1186/s12885-019-6311-z
Sipilä R, Hintsa T, Lipsanen J, Tasmuth T, Estlander AM, Kalso E. The relationship between anger regulation, mood, pain, and pain-related disability in women treated for breast cancer. Psychooncology. 2019;28(10):2002-8. doi: https://doi.org/10.1002/pon.5182
How to Cite
Copyright (c) 2021 Medicni perspektivi (Medical perspectives)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.
Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.