The criteria of diagnostic pulmonary tuberculosis activity in patients working in hazardous working conditions.
DOI:
https://doi.org/10.26641/2307-0404.2018.3(part1).142387Keywords:
diagnostics, criteria of pulmonary tuberculosis activity, hazardous working conditionsAbstract
The article presents the analysis of clinical examination data of 76 patients with tuberculosis: 51 patients (1 group) who worked in hazardous conditions and 25 patients (2 group) who had no contact with hazardous factors. Changes in hematological parameters in patients have been analyzed and a new method for diagnosis of specific tuberculosis activity (SKAT) has been proposed. It was found that in patients under adverse conditions of production (group 1) pulmonary tuberculosis was detected 1,7 times (p<0,05) more often at the age of 40 years and older, unlike the second group, in which the disease was diagnosed 2,9 times more often (p<0,05) at the age of 21-30 years. In patients of the first group Mycobacteria tuberculosis were detected 1,4 times more often (p<0,05) as well. In patients with pulmonary tuberculosis, there were similar changes in hematological parameters (increasing number of leukocytes, eosinophils and erythrocyte sedimentation rate), which is characteristic for granulomatous inflammation. A new method for the diagnosis of tuberculosis specific activity (SKAT) allows to determine the severity of tuberculosis activity and severity of the disease course.References
Chernyshova OM, Tkach SI, Korobchanskyi VO, Melnyk OG, Chernova SD. [Determination of immunological risk criteria for the occurrence and course of bronchopulmonary diseases in the machine-building industry]. Kyiv, MOH of Ukraine, 2011;44. Ukrainian.
Feshchenko YuI, Lytvynenko NA, Pohrebna MV et al. [Treatment of patients with chemo-resistant tuberculosis and tuberculosis with the extended increased resistance Mycobacteria tuberculosis to anti-TB drugs: the main causes of low results]. Tuberculosis, lung diseases, HIV infection. Ukrainian scientific-practical specialized journal. 2016;2(25);20-22. Ukrainian.
Lytvynenko NA. [Risk factors concerning the occurrence of extended and pre-extended resistance of MTB among patients with multidrug-resistant tuberculosis]. Modern medical technology. 2014;2;36-42. Ukrainian.
Melnyk VM, Novozhylova IO, Matusevych VG. [Chemo-resistant tuberculosis: the state of the problem in Ukraine]. Ukr. med. chasopys. 2013;6;26-28. Ukrainian.
Poteiko PI, Konstantynovskaia OS, Solodiankyn AS [Necessity of identification of Mycobacterium bovis among patients with pulmonary tuberculosis in Ukraine]. Medical Drugs for Humans. Modern Issues of Pharmacotherapy and Prescription of Medicine. 1-st International scientific-practical conference. Kharkov, NUPh, 2017;2;264-268. Russian.
Tkach SI, Poteiko PI, Rohozhyn AV, Konstantynovskaia OS. [A method for diagnosing of the pulmonary tuberculosis of specific activity]. Patent for utility model N 122489. 2018;1;4. Ukrainian.
Barbovy AI, Zhurylo OA, Trofimova PS, Myronchenko SV [Modern methods of tuberculosis diagnosis]. Tuberculosis, lung diseases, HIV infection. Ukrainian scientific-practical specialized journal. 2018;1(32);8-14. Ukrainian.
Tkach SI, Poteiko PI. [The procedure for establishing the connection of the disease with working conditions in patients with tuberculosis and konioituberculosis]. Tutorial. Kharkiv, KMAPE, 2012;20. Ukrainian.
Tkach SI, Tkach YuI. [The importance of hematological indicators for preventive medical examinations of workers in hazardous working conditions]. Southern Ukrainian medical scientific journal. 2016;14(14);112-5. Russian.
Tkach SI, Melnyk OG, Chernova SD. [Bronchoobstructive syndrome in patients with coniotuberculosis of workers in machine building]. Vestnyk hyhyeny i epydemyolohyy. 2010;14;73-76. Russian.
Todoriko LD, Petrenko VI, Shevchenko OS. [Prospects for overcoming of tuberculosis in Ukraine]. Tuberculosis, lung diseases, HIV infection. Ukrainian scientific-practical specialized journal. 2016;1(24);72-78. Ukrainian.
Feshchenko YuI, Melnyk VM. [Organization of control over chemo-resistant tuberculosis in Ukraine]. Kyiv, Zdorovia, 2103;703. Ukrainian.
Downloads
How to Cite
Issue
Section
License
Copyright (c) 2018 Medicni perspektivi (Medical perspectives)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.
Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.