Optimization of surgical treatment of epidermoid brain tumors.

Authors

  • A. G. Sirko
  • D. N. Romanukha

DOI:

https://doi.org/10.26641/2307-0404.2015.3.53686

Keywords:

epidermoid tumor, epidermoid cysts, сholesteatoma, surgical treatment, complications, epidermoid recurrence

Abstract

Despite the relatively rare occurrence of epidermoid brain tumors (EBT), high rates of postoperative mortality and a high incidence of tumor recurrence are marked in the operated patients. The purpose of research is to improve treatment results of patients with EBT by determining optimal treatment tactic. A retrospective research of 17 patients with verified EBT was carried out and literary sources on various problems of their surgical treatment were analyzed. By localization EBT were devided as following: subtentorial localization was observed in 8 (47%) patients, supratentorial – in 7 (41%). Two patients (12%) had suprasubtentorial localisation of EBT. Intra- and postoperative complications were observed in 3 (18%) of cases; of patients 18% (3 patients) were discharged with deterioration of neurological sta­tus. The main purpose in EBT removing is total tumor removal in conditions of preventing iatrogenic injury of vessels, nerves and functionally important brain areas. Radical removal of cholesteatomas using microsurgical techniques with relatively low com­plication level provides a long disease-free period and a high quality of life of operated patients.

Author Biographies

A. G. Sirko

SE "Dnipropetrovsk medical academy of Health Ministry of Ukraine"
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

D. N. Romanukha

SE "Dnipropetrovsk medical academy of Health Ministry of Ukraine"
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

References

Trosh RM, Lisyanyy AM, Gudkov VV, Onish-chenko PM, Fedirko VO. [Aseptic meningitis with epi-dermoid tumors of the posterior fossa: prevention and treatment]. Ukrainskiy neyrokhirurgicheskiy zhurnal. 2000;3:56-60. Russian. 2. Kulyk OV. [Combined treatment of gliomas fron-to-callosal location]. In-t nejrohirurgii' im. akad. A.P. Romodanova AMN Ukrai'ny: Avtoref. dys. na zdobuttja nauk. stupenja kand. med. nauk. 2008;47. Ukrainian. 3. Lisjanyj OM. [Epidermoid tumors of the posterior cranial fossa (diagnosis and treatment)]. In-t nejrohirurgii' im. akad. A.P. Romodanova AMN Ukrai'ny: Avtoref. dys. na zdobuttja nauk. stupenja kand. med. nauk. 2000;23. Ukrainian. 4. Trosh RM, Lisyanyy AM, Gudkov VV, Onish-chenko PM. [Evaluating the effectiveness of surgical treatment in patients with epidermoid tumors of the posterior fossa]. Ukrainskiy neyrokhirurgicheskiy zhur¬nal. 2000;2:60-64. Russian. 5. Chowdhury FH, Haque MR, Sarker MH. Intracranial epidermoid tumor; microneurosurgical mana¬gement: an experience of 23 cases. Asian J Neurosurg. 2013Jan;8(1):21-8. 6. Kato K, Ujiie H, Higa T, Hayashi M, Kubo O, Okada Y. Clinical presentation of intracranial epider-moids: a surgical series of 20 initial and four recurred cases. Asian J Neurosurg. 2010 Jan-Jun;5(1):32–40. 7. Cobbs CS, Pitts LH, Wilson CB. Epidermoid and dermoid cysts of the posterior fossa. Clin Neurosurg. 1997;44:511-28. 8. Doyle KJ, De la Cruz A. Cerebellopontine Angle Epidermoids: results of Surgical Treatment. Skull base surgery. 1996;6(1):27-33. 9. Bründl E, Schödel P, Ullrich O, Brawanski A, Schebesch K. Epidermoids Of The Posterior Cranial Fossa – Surgical Experiences & Review Of Literature. The Int J Neurosurg. 2014;10(1). 10. Kobata H, Kondo A, Iwasaki K. Cerebellopontine angle epidermoids presenting with cranial nerve hyper-active dysfunction: pathogenesis and long-term surgical results in 30 patients. Neurosurg. 2002;50:276-85. 11. Kornienko VN, Pronin IN. Diagnostic Neurora-diology. Berlin: Springer. 2009;580. 12. Schiefer TK, Link MJ. Epidermoids of the cere-bellopontine angle: a 20-year experience. Surgical neuro-logy. 2008;70:584-90. 13. Lopes M, Capelle L, Duffau H, Kujas M, Sichez JP, Van Effenterre R. Surgery of intracranial epidermoid cysts. Report of 44 patients and review of the literature. Neurochirurgie. 2002 Feb;48(1):5-13. 14. Lynch JC, Aversa A, Pereira C. Surgical strategy for intracranial dermoid and epidermoid tumors: an experience with 33 Patients. Surg Neurol Int. 2014;5(163). 15. Akar Z, Tanriover N, Tuzgen S, Kafadar AM, Ku-day C. Surgical treatment of intracranial epidermoid tumors. Neurol Med Chir. 2003;43:275-80.

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Published

2015-09-23

How to Cite

1.
Sirko AG, Romanukha DN. Optimization of surgical treatment of epidermoid brain tumors. Med. perspekt. [Internet]. 2015Sep.23 [cited 2024Nov.26];20(3):61-7. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/53686

Issue

Section

CLINICAL MEDICINE