Neurochemical and behavioral processes in gerontogenesis in conditions of experimental hyperglycemia.
DOI:
https://doi.org/10.26641/2307-0404.2018.2.133691Ключевые слова:
experimental diabetes, experimental hyperglycemia, alloxan, diabetic encephalopathy, glial fibrillary acidic proteinАннотация
Many researchers are increasingly interested in the relation between diabetes and diabetic encephalopathy. At the moment, there are various experiments where this issue is considered. But despite prolonged studying, it is impossible to investigate this problem to the end. Cognitive deficit in hyperglycemia is also connected with aging. In the aging processes as in hyperglycemia the same pathogenetic factors play a role in the aging of the brain. It is also necessary to deeply analyze the neurochemical processes occurring in the brain in diabetes mellitus. The high incidence of complications is caused by tissue metabolism impairment in hyperglycemia. The study of neurochemical bases of brain activity is one of the leading and promising directions in the modern neuropathology. Scientists of different countries are searching for neurospecific damage markers of the brain substance in hyperglycemia.
Библиографические ссылки
Babah VN. [Treatment strategy and features of the clinic of mental disorders and psychosocial problems in patients with diabetes mellitus]. Mizhnarodnyi endokrinologichnyi zhurnal. 2005;1:92-98. Russian.
Bobyreva LE. [Effect of phenolic antioxidants on the development of alloxan diabetes in rats]. Eksperimental'naya i klinicheskaya farmakologiya. 1997;60(3):51-53. Russian.
Borysiuk MV, Dosenko VYe, Byts YuV. [Condition of the elastolic system of the pancreas in the modeling of diabetes mellitus]. Fiziologichnyi zhurnal. 2002;48(5):17-21. Ukrainian.
Pal'chikova NA, Kuznecova NV, Kuz'minova OI, Selyatitskaya VG. [Hormonal-biochemical features of alloxan and streptozotocin models of experimental diabetes]. Byulleten' SO RAMN. 2013;33(6):18-24. Russian.
BornsteinNM, Korczyn A, Brainin M, Guekht A,SkoogI.[Diabetes and the brain: questions and problems]. Effektivnaya farmakoterapiya. 2014;39:50-56. Russian.
Yemel'yanov VV, Meshhaninov VN, Sarapul'cev PA. [Metabolic factors of accelerated aging of the organism in patients with type 2 diabetes mellitus and their correction]. Gospital'nyy vestnik. 2007;2:20-32. Russian.
Leberfarb EYu, Rykova VI, Kolosova NG, et al. [Changes in the composition of rat proteoglycans in rats with age]. Byulleten' eksperimental'noy biologii i mediciny. 2008;146(12):691-3. Russian.
Korkina MV, Elfimova EV. [Diabetes and cognitive aging]. Zhurnal nevrologii i psihiatrii. 2004;3:80-84. Russian.
Yemel'yanov VV, Ponomareva OS, Plotnikova EP, Severina TI, Kochergina MV. [Metabolic disorders and the rate of aging of an organism in patients with type 1 diabetes mellitus]. International Scientific and Practical Conference "Age-associated and gender peculiarities of health and disease". 2016;125-33. Russian.
GuzVA.[Mechanisms of defeat of the central and peripheral nervous system in conditions of experimental diabetes mellitus]. Medicni perspektivi. 2009;XIV(3):4-14. Ukrainian.
Zinovieva OH. [Mechanisms of the functioning of the central and peripheral nervous system in conditions of experimental diabetes mellitus]. Medicni perspektivi. 2012;XVII(4):7-14. Ukrainian.
Mikhalyova LM, Gorshunova NK, Andryeva NV. [Diabetic microangiopathy in the elderly and senile age: clinical and morphological diagnostics and treatment]. Moskva, Medicinskoe informacionnoe agentstvo. 2009;176. Russian.
Smirnov AV, Shmidt MV, Pan'shin NG, Kuznecova VA. [Morphological changes in the hippocampus in the experimental modeling of diabetic encephalopathy]. Volgogradskiy nauchno-medicinskiy zhurnal. 2016;2:37-39. Russian.
Lankin VZ, Lisina MO, Arzamasceva NE, Konovalova GG, Nedosugova LV, Kaminnyj AI, Tihaze AK, Ageev FT, Kuharchuk VV, Belenkov YuN. [Oxidative stress in atherosclerosis and diabetes]. Byulleten eksperimental'noy biologii i mediciny. 2005;140(7):48-51. Russian.
Hrytsiuk MI, Boichuk TM, Petryshen OI. [Comparative characteristic of experimental models of diabetes mellitus]. Svit medycyny ta biologii. 2014;2(44):199-202. Ukrainian.
Zinkovich II,KhripachenkoIA, Kedenko LA, Savustianenko AV. [The role of autonomic regulation in the development of alloxan-induced diabetes mellitus in rats]. Endokrinologiia. 2005;10(1):35-40. Russian.
Yesin RG, Hajrullin IH, Esin OR. [Modern ideas about the mechanisms of cognitive disorders in diabetes mellitus]. Medicinskiy al'manah. 2013;1(25):135-7. Russian.
Sosina VB, Zaharov VV, Jahno NN. [Nondemantic cognitive impairments in patients with type 2 diabetes mellitus]. Nevrol. zhurnal. 2010;4:25-30. Russian.
GuzVA.[Condition of conditioned reflex and tentative-research activity of rats of different ages under conditions of aloxane diabetes]. Medicni perspektivi. 2011;XVI(1):4-10. Ukrainian.
StrokovIA, Zaharov VV, Strokov KI. [Diabetic encephalopathy]. Nevrologiya, neyropsihiatriya, psihosomatika. 2012;2S:30-40. Russian.
Celuyko SS, Krasavina NP, Korneeva LS, Lashin SA, Ostronkov VS. [Morphofunctional characteristics of the pancreas and lung in experimental hyperglycemia with dihydroquercetin]. Еdited by Celuyko SS. Blagoveshhensk, IPK ODEON. 2017;150. Russian.
Chernysheva EN, Panova TN. [Biological age and rate of aging in patients with metabolic syndrome, depending on anthropometric indicators]. Kubanskiy nauchnyy medicinskiy vestnik. 2011;6:178-81. Russian.
Chernaya VI. [Influence of ionizing radiation on the protein content of intermediate gley filaments and the state of brain proteolysis]. Visnyk Dnipropetrovskogo derzhavnogo agrarnogo universytetu. 2010;2:26-29. Russian.
Chugunov PA, Semenova IV. [Diabetes mellitus and cognitive impairment]. Saharn. diab. 2008;161-8. Russian.
Mozhejko LA.[Experimental models for the study of diabetes mellitus. Part 1. Alloxan diabetes]. Zhurnal Grodnenskogo gosudarstvennogo medicinskogo universiteta. 2013;3:26-28. Russian.
Yastrebov AP, Meshhaninov VN. [Aging, lipid peroxidation and bio-age]. Yekaterinburg, Ural'skiy sledopyt. 2005;220. Russian.
Antia BS, Okokon JE. [Hypoglyacaemic effect of aqueous leaf extract of Persea Americana (Mill,) on alloxan induced diabetic rats]. Indian J Pharmacol. 2005;37(5):325-26.
Levin OS, Babkina OV. [Cerebrum diabeticum: is there a diabetic encephalopathy?]. Effektivnaya farmakoterapiya. 2016;29:32-36.
Bloom R, Schnaider-Beeri M, Rayona-Springer R, Heymann A, Dabush H, Bar L, Slater S, Rassovsky Y, Bahar-Fuchs A. [Computerized cognitive training for older diabetic adults at risk of dementia: Study protocol for a randomized controlled trial]. Alzheimers Dement (N Y). 2017;3(4):636-50.
Das J, Vasan V, Sil PC. [Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac oxidative stress and apoptosis]. Toxicol. Appl Pharmacol. 2012;258:296-308.
Dinesh KJ, Raj KA. [Anomalies in alloxan-iduced diabetic model: it is better to standardize it first].Ind.J. of Pharmacology. 2011;1(43):91.
Elsner M, Gurgul-Convey E, Lenzen S. [Relative importance of cellular uptake and reactive oxygen species for the toxicity of alloxan and dialuric acid to insulin- producing cells]. Free Radic Biol Med. 2006;41:825-34.
Macedo CS. [Experimental model of induction of diabetes mellitus in rats]. Plastic surgery, laboratory of plastic surgery:Sao Paulo- Paulista School of Medicine. 2005;2-5.
Frontczak-Baniewicz M, Struzynska L, Andrychowski J. [Ultrastructural and immunochemical studies of glial scar formation in diabetic rats]. Acta. neurochir. suppl. 2010;106:51-55.
Gabbay KH, Merola LO, Field RA. [Sorbitol pathway: presence in nerve and cord with substrate accumulation in diabetes]. N. Engl. J. Med. 1988;319(9):542-8.
Golalipour MJ, Kaboli S, Kafshgiri, Ghafari S. Folia Morphol. 2012;71(2):71-77.
Malik RA, Masson ЕА, Sharma АК. [Hypoxic neuropathy: relevance to human diabetic neuropathy]. Science. 1966;151(707):209-10.
Federiuk IF. [Induction of type 1 diabetes rnellitus in’ laboratory rats by use of attoxan route of administration, pitfalls, and insulin treatment]. Comprehensive Medicine. 2004;54:252-7.
Jing L, He Q, Zhang J, Li PA. [Temporal Profile of Astrocytes and Changes of Oligodendrocyte-Based Myelin Following Middle Cerebral Artery Occlusion in Diabetic and Non- diabetic Rats]. Int. J. Biol. Sci. 2013;9(2):190-9. doi: http://dx.doi.org/10.7150/ijbs.5844
Kaminitz A, Stein J,YanivI.[The vicious cycle of apoptotic beta-cell death in type 1 diabetes]. Immunol. Cell. Biol. 2007;85:582-9.
King AJ. [The use of animal models in diabetes research]. Br.J. Pharmacol. 2012;166(3):877-94.
Latha Velayudhan, Michaela Poppe, Nicola Archer. [Risk of developing dementia in people with diabetes and mild cognitive impairment]. BJP. 2010;196:36-40.
Lenzen S. [The mechanisms of alloxan- and streptozotocin-induced diabetes]. Diabetologia. 2008;51:216-26.
Li ZG, Zhang W, Sima AA. [The role of impaired insulin / IGF action in primary diabetic encephalopathy]. Brain Res. 2005;1037(1-2):12-24.
Min TS, Park SH. [Therapy of Diabetes Mellitus Using Experimental Animal Models]. Asian-Aust. J. Anim. Sci. 2010;23(5):672-9.
Szkudelski T. [The mechanism of alloxan and streptozotocin action B ceils of the rat pancreas]. Physiology. Res. 2001;50:536-46.
Tesfaye S, Malik R, Ward JD. [Vascular factors in diabetic neuropathy]. Diabetologia.1994;37(9):847-54.
Xu Y, Zhou H, Zhu Q. [The Impact of Microbiota-Gut-Brain Axis on Diabetic Cognition Impairment]. Front. Aging Neurosci; 2017
Vermeer SE, Den Heijer T, Koudstaal PJ. [Incidence and risk factors of silent brain infarcts in the population- based Rotterdam Scan Study]. Stroke. 2003;34(2):392-6.
Yan L-J. [Pathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress]. J. Diab. Research. 2014:1-11.
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