Influence of ICG-technology on the results of surgical treatment of early forms of breast cancer
DOI:
https://doi.org/10.26641/2307-0404.2021.2.234516Ключевые слова:
breast cancer, surgical tactics, intraoperative ICG-technologyАннотация
Breast cancer (BC) is one of the most common causes of death in women up to 50 years old. For today the choice of an adequate methods of surgical intervention and the need for an adequate surgical adjuvant therapy, quality of life of patients after surgeryis are important. The aim of our study was to select the volume of surgery for breast cancer using the technique of intraoperative identification of the sentinel lymph node (intraoperative ICG technology) and to evaluate the results of its urgent histological examination. It was shown that the most common method of surgery in patients who underwent intraoperative ICG technology was quadrantectomy, which was performed in 27 cases (54%), rarely subcutaneous mastectomy was performed (30%) and radical mastectomy (by Madden) – 16%. In the control group, priority was given to radical removal of the breast (63.2% of cases); partial resection (by U. Veronesi) was performed in 33.3% of patients, and subcutaneous mastectomy – in 3.5%. Pathomorphological examination of the sentinel lymph node during its intraoperative imaging using ICG-technology established metastatic lesion in 10 of 50 cases (20%) in the main group. The obtained results of the assessment of the regional lymph dissection size in the main group indicate its adequate nature to ensure the radicality of surgical treatment. In our opinion, this is one of the important preliminary conclusions of this study, because to assess the clinical significance of signal lymph node (SLN) analysis as a marker of regional tumor spread, firstly it is necessary to be sured that existing surgical techniques provide radical tumor removal.
Библиографические ссылки
Trubnikova EV, Nguen TH, Belous AS, Shulgin IYu. [Analysis of morbidity rates in oncologically unfavorable areas]. Auditorium. 2018;3(19):31-5. Russian.
Antomonov MYu. [Mathematical processing and analysis of biomedical data]. Medinform. 2018. p. 579. Russian.
Vaninov AS. [Malignant neoplasms as the highest priority medical and social problem of the health care system]. Bulletin of Science and Practice. 2019;5(11):120-30. Russian. doi: https://doi.org/10.33619/2414-2948/48/16
Minakov SN. [Morbidity and mortality from cancer of the breast and female genital organs (cervix, uterine body, ovaries) in the Moscow region in 2015]. Malignant tumors. 2017;1:67-9. Russian. doi: https://doi.org/10.18027/2224-5057-2017-1-67-69
Mirhamidova SM, Dinmuhammadiev NA. [Featu¬res of the prevalence of cancer]. Young scientist. 2016;20:84-7. Russian.
Ragimzade SE. [Breast cancer: epidemiology, risk factors, pathogenesis, diagnosis, prognosis]. Inter¬national Medical Journal. 2017;23(2):60-4. Russian.
Ruden VV, Moskviak-Lesniak DYe, Hutor TH. [Scientific and methodological bases of formation of the limit value of absolute risk in the possible occurrence / development of breast cancer (C50) in females]. Clinical and experimental pathology. 2014;8(3):142-9. Ukrainian.
Savenkov OYu, Romanukha KH, Khomenko AV. [Improving the tactics of surgical treatment of early forms of breast cancer in women to prevent the development of secondary lymphedema]. Bulletin of problems of biology and medicine. 2020;1(155):200-3. Ukrainian. doi: https://doi.org/10.29254/2077-4214-2020-1-155-200-203
Francuzova IS. [Analysis of risk factors for breast cancer]. International Research Journal. 2019;3(81):68-74. Russian.
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2018;68(6):394-424. doi: https://doi.org/10.3322/caac.21492
Загрузки
Опубликован
Как цитировать
Выпуск
Раздел
Лицензия
Copyright (c) 2021 Medicni perspektivi (Medical perspectives)
Это произведение доступно по лицензии Creative Commons «Attribution» («Атрибуция») 4.0 Всемирная.
Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.
Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.