Nosomorphosis of diseases caused by urogenital infections

A.D. Diudiun; M.Y. Polion; N.N.  Polion

doi:10.26641/2307-0404.2021.3.242083

Авторы

A.D. Diudiun Dnipro State Medical University, V. Vernadsky str., 9, Dnipro, 49044, Ukraine https://orcid.org/0000-0002-8374-3023
M.Y. Polion Dnipro State Medical University, V. Vernadsky str., 9, Dnipro, 49044, Ukraine https://orcid.org/0000-0001-9307-1411
N.N. Polion Dnipro State Medical University, V. Vernadsky str., 9, Dnipro, Ukraine https://orcid.org/0000-0002-5791-0254

DOI:

https://doi.org/10.26641/2307-0404.2021.3.242083

Ключевые слова:

urogenital infections, clinic, diagnostics

Аннотация

One of the real threats to the health of the next generation are diseases caused predominantly by sexually transmitted infections (STIs). The frequency of these diseases is constantly increasing among the population of Ukraine and other countries. The aim of our work was to establish the features of the clinical manifestations of diseases caused by urogenital infections (UGI) at the present stage. Under our supervision, there were 577 patients with STIs, 83% of the patients were at the age of the highest socio-economic and sexual activity. A complex of methods for examining the patients included: physical and general clinical studies, laboratory research to identify STIs and conditionally pathogenic microorganisms. A comprehensive complex examination made it possible to identify urogenital chlamydia in 395 (68.5%), trichomoniasis – in 381 (66.03%), ureaplasmosis – in 240 (41.6%), microorganisms associated with bacterial vaginosis – in 80 (13.9%) and urogenital candidiasis – in 75 (13.0%). Monoinfection was diagnosed only in 61 (10.6%) of patients. Among the patients examined, the inflammatory process of the genitourinary organs was supported by two infectious agents in 487 (84.4%), three or more – in 52 (9.0%) of the observed patients. The affection of the urogenital system with STIs occurs with several infectious agents. Clinical manifestations of diseases caused by STIs are asymptomatic or low-symptomatic. The asymptomatic course of diseases caused by STIs leads to a chronic long-term course of the pathological process with the formation of multi-focal lesions and residual phenomena, including proliferative neoplasms.

Библиографические ссылки

Antomonov MYu. [Mathematical processing and analysis of biomedical data.]; 2017. p. 578. Russian.

Diudiun AD, Polion NM, Gorbuntsov VV. [Secnidazole in complex treatment of patients with urogenital trichomoniasis]. Dermatovenereology Cosmetology Sexo¬pathology. 2016;1-4:287-92. Ukrainian.

Ivchenko GI, Medvedev YuI. [Introduction to Mathematical Statistics. "Statistics knows everything" 2, rev. and add.]; 2017. p. 608. ISBN 978-5-9710-4535-9. Russian.

Kamyshnikov VS. [Methods of clinical laboratory research]. 10th ed. Moskva: MEDpress-in form; 2020. p. 736. ISBN 978-5-00030-774-8. Russian.

Mavrov GI, Lukyanov IE. [Medical, social and clinical characteristics of patients with mixed urogenital infection]. Dermatovenereology Cosmetology Sexopathology. 2016;1-4:255-9. Russian.

Antinori S, Pezzani MD. Uncomplicated and complicated urinary tract infections in adults: The infec¬tious diease's specialist perspective. In: Tonolini M., editor. Imaging and Intervention in Urinary Tract Infections and Urosepsis. Springer International Publishing; 2018. p. 17-33. doi: https://doi.org/10.1007/978-3-319-68276-1_3

Jane Rowley, Stephen Vander Hoorn,Eline Korenromp, Nicola Low, Magnus Unemo,Laith J AbuRaddad,R Matthew Chico, Alex Smolak,Lori Newman, Sami Gottlieb, Soe Soe Thwin,Nathalie Brouteta & Mela¬nie M Taylora. Chlamydia, gonorrhoea, trichomoniasis and syphilis: global prevalence and incidence estimates, 2016. Bull World Health Organ 2019;97:548-62P. doi: https://doi.org/10.2471/BLT.18.228486

Chu CM, Lowder JL. Diagnosis and treatment of urinary tract infections across age groups. Am J Obstet Gynecol. 2018 Jul;219(1):40-51. doi: https://doi.org/10.1016/j.ajog.2017.12.231

Shipman SB, Risinger CR, Evans CM, et al. High Prevalence of Sterile Pyuria in the Setting of Sexually Transmitted Infection in Women Pre¬sen¬ting to an Emergency Department. West J Emerg Med. 2018 Mar;19(2):282-6. doi: https://doi.org/10.5811/westjem.2017.12.35605

Hein DC, Wagenlehner FME. Current diagnosis and treatment of sexually transmitted infections. Urologia. 2018 Dec;57(12):1436-44.

Johnathan M Sheele, Justin Smith, Joshua D Niforatos, Emily Wessling, Benjamin Hilliker, Bradley Bragg, Ed Mandac. History, Physical Examination, and La¬boratory Findings Associated with Infection and the Empiric Treatment of Gonorrhea and Chlamydia of Women in the Emergency Department. Cureus. 2019 Dec 27;11(12):e6482.

Payam Behzadi, Elham Behzadi, Edyta Ag¬nieszka Pawlak-Adamska. Urinary tract infections (UTIs) or genital tract infections (GTIs)? It's the diagnostics that count. Jour¬nal ListGMS Hyg Infect Controlv. 14; 2019. PMC6449866.

Gottesman T, Yossepowitch O, Samra Z, Rosenberg S, Dan M. Prevalence of Mycoplasma genitalium in men with urethritis and in high risk asymptomatic males in Tel Aviv: a prospective study. Int J STD AIDS. 2017 Feb;28(2):127-32. doi: https://doi.org/10.1177/0956462416630675

Sarier M, Sepin Ozen N, Guler H, Duman I, Yüksel Y, Tekin S, Yavuz AH, et al. Prevalence of Sexually Transmitted Diseases in Asymptomatic Renal Transplant Recipients. Exp Clin Transplant; 2018 Apr 4.