The incidence of benign and malignant tumors among adults with long-term physical disabilities

Авторы

DOI:

https://doi.org/10.26641/2307-0404.2024.3.313671

Ключевые слова:

tumor formations, incidence, people with long-term physical disabilities

Аннотация

People with long-term physical disabilities also suffer from different types and nature of tumors as well as general population. Unfortunately, the information about the frequency of these diseases among the specified contingent is very deficient. The objectives of the study were to determine the incidence of benign and malignant neoplasia among the adults and elderly with physical disabilities and to indicate the risk factors for the appearance and development of tumors in this population. In this descriptive survey, 186 people, living in the largest home on the Balkan Peninsula for adults and elderly people with long-term physical disabilities were studied in 2021. 82.79% of the residents were over 51 years of age and almost all of them are inhabited by two residents. 42.47% of the respondents were men and 57.52% – women. Data on the demographic characteristics of the respondents, including their personal lifestyle and self-reported diagnosis of presence and/or history of a tumor formation, were collected through a semi-structured interview. The verification of the collected information about the incidence of benign and malignant lesions among adults with physical disabilities was carried out by means of the application of the second research method – content analysis based on the medical records. For processing and analysis of the collected data, it was used statistical software – IBM SPSS Statistics V21.0. The results showed a significantly high rate in the prevalence of tumor formations in the sample – 24.19%. The pre-cancerous formations have the highest incidence among residents – 42.22% with the most common variant – chronic form of cholecystitis combined with cholelithiasis (37.77%). Prostatic hyperplasia and uterine leiomyoma are the leading benign lesions in male residents – 11.11%, in female respondents – 11.11% respectively. The predominant form of cancer is breast carcinoma – 8.88%. The research found a high prevalence of tumor formations among adult patients with long-term physical disabilities. The harmful impact of a number of behavioral habits and health determinants significantly contributes to this negative tendency.

Библиографические ссылки

Australian institute of health and welfare. People with disability in Australia [Internet]. 2020 [cited 2024 Mar 12]. Available from: https://www.aihw.gov.au/reports/disability/people-with-disability-in-australia

ICDR Toolkit-Health Disparities and Disabilities in Research [Internet]. 2020 [cited 2024 Mar 12]. Available from: https://icdr.acl.gov/system/files/resources/HFW%20Toolkit%20Final.pdf

Centers for disease control and prevention. Cancer screening prevalence among adults with disabilities [Internet]. 2019 [cited 2024 Mar 12]. Available from: https://www.cdc.gov/cancer/dcpc/research/articles/screening-disabilities.htm

Fowler H, Belot A, Ellis L, et al. Comorbidity prevalence among cancer patients: a population-based cohort study of four cancers. BMC Cancer. 2020;20(1):2. doi: https://doi.org/10.1186/s12885-019-6472-9

Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Abate D, et al. Global, Regional, and Na-tional Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncol. 2019 Dec 1;5(12):1749-68. doi: https://doi.org/10.1001/jamaoncol.2019.2996. Erratum in: JAMA Oncol. 2020 Mar 1;6(3):444. doi: https://doi.org/10.1001/jamaoncol.2020.0224. Erratum in: JAMA Oncol. 2020 May 1;6(5):789. doi: https://doi.org/10.1001/jamaoncol.2020.0741. Erratum in: JAMA Oncol. 2021 Mar 1;7(3):466. doi: https://doi.org/10.1001/jamaoncol.2020.8307

Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of in-cidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74(3):229-63. doi: https://doi.org/10.3322/caac.21834

Ubago-Guisado E, Rodríguez-Barranco M, Ching-López A, et al. Evidence Update on the Relationship between Diet and the Most Common Cancers from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: A Systematic Review. Nutrients. 2021;13(10):3582. doi: https://doi.org/10.3390/nu13103582

Marino P, Mininni M, Deiana G, Marino G, Divella R, Bochicchio I, et al. Healthy lifestyle and cancer risk: modifiable risk factors to prevent cancer. Nutrients. 2024;16(6):800. doi: https://doi.org/10.3390/nu16060800

de Martel C, Georges D, Bray F, Ferlay J, Clifford GM. Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis. Lancet Glob Health. 2020;8(2):e180-e190. doi: https://doi.org/10.1016/S2214-109X(19)30488-7

Dikova K, Yaneva R. National center for public health and analysis of the ministry of health. Sofia: Healthcare; 2021. р. 1313-1907.

National strategy for long-term care in the Republic of Bulgaria, 2014-2020. 2020. p. 11-14.

Kim YE, Lee YR, Yoon SJ, Kim YA, Oh IH. Years of Life Lost due to Premature Death in People with Disabilities in Korea: the Korean National Burden of Disease Study Framework. J Korean Med Sci. 2019;34(2):e22. doi: https://doi.org/10.3346/jkms.2019.34.e22

U.S. Department of Health and Human Services. Healthy People 2020. Disparities [Internet]. 2020 [cited 2024 Mar 12]. Available from: https://odphp.health.gov/healthypeople

National center on birth defects and developmental disabilities. (2020, April 23). Increasing physical activity among adults with disabilities. Centers for disease control and prevention [Internet]. 2020 [cited 2024 Mar 12]. Available from: https://www.cdc.gov/ncbddd/disabilityandhealth/pa.html

Centers for disease control and prevention. Disability and health data system (DHDS) [Internet]. 2023 [cited 2024 Mar 12]. Available from: http://dhds.cdc.gov

Chiu TY. Predictors of use of preventative health services for people with disabilities in taiwan. Int J Environ Res Public Health. 2021;18(4):1661. doi: https://doi.org/10.3390/ijerph18041661

Clina JG, Sayer RD, Gorczyca AM, et al. Weight history of individuals with and without physical disability in the International Weight Control Registry. Obes Sci Pract. 2023;10(1):e733. doi: https://doi.org/10.1002/osp4.733

Washburn RA, Ptomey LT, Gorczyca AM, et al. Weight management for adults with mobility related disabilities: Rationale and design for an 18-month randomized trial. Contemp Clin Trials. 2020;96:106098. doi: https://doi.org/10.1016/j.cct.2020.106098

Carty C, van der Ploeg HP, Biddle SJ, Bull F, Willumsen J, Lee L, et al. The first global physical activity and sedentary behavior guidelines for people living with disability. Journal of Physical Activity and Health. 2021;18(1):86-93. doi: https://doi.org/10.1123/jpah.2020-0629

PDQ Cancer genetics editorial board. Genetics of breast and gynecologic cancers (PDQ®): health professional version. 2024 Apr 4. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002 [cited 2024 Mar 12]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK65767/

White MC, Kavanaugh-Lynch MM, Davis-Patterson S, Buermeyer N. An expanded agenda for the primary prevention of breast cancer: charting a course for the future. Int J Environ Res Public Health. 2020;17(3):714. doi: https://doi.org/10.3390/ijerph17030714

Rodríguez-Palacios DÁ, Colorado-Yohar SM, Velten M, Vaamonde-Martín RJ, Ballesta M, Chirlaque MD. Incidence and trend of type I and II endometrial cancer in women from two population-based European Cancer Registries (1998-2012). Int J Environ Res Public Health. 2022;19(7):3789. doi: https://doi.org/10.3390/ijerph19073789

Weishaupt J. Endometrial cancer: Access denied – a review of the forgotten voice of mental and physical disability in gynaecology oncology in Australia. J Women's Health Care. 2019;8:476. doi: https://doi.org/10.35248/2167-0420.19.8.476

Hutt S, Mihaies D, Karteris E, Michael A, Payne AM, Chatterjee J. Statistical meta-analysis of risk factors for endometrial cancer and development of a risk prediction model using an artificial neural network algorithm. Cancers (Basel). 2021;13(15):3689. doi: https://doi.org/10.3390/cancers13153689

Katagiri R, Iwasaki M, Abe SK, et al. Reproductive Factors and Endometrial Cancer Risk Among Women. JAMA Netw Open. 2023;6(9):e2332296. doi: https://doi.org/10.1001/jamanetworkopen.2023.32296

Simms KT, Yuill S, Killen J, et al. Historical and projected hysterectomy rates in the USA: Implications for future observed cervical cancer rates and evaluating pre-vention interventions. Gynecol Oncol. 2020;158(3):710-8. doi: https://doi.org/10.1016/j.ygyno.2020.05.030

Gultekin M, Ramirez PT, Broutet N, et al. World Health Organization call for action to eliminate cervical cancer globally. International Journal of Gynecologic Cancer. 2020;30:426-7. doi: https://doi.org/10.1136/ijgc-2020-001285

Abebe M, Eshetie S, Tessema B. Prevalence of sexually transmitted infections among cervical cancer suspected women at University of Gondar Comprehensive Specialized Hospital, North-west Ethiopia. BMC Infect Dis. 2021;21(1):378. doi: https://doi.org/10.1186/s12879-021-06074-y

Kucuk S, Ercihan E, Ucar Uncu A, et al. A retrospecti̇ve evaluation of the epithelial lesions/neoplasms of the gallbladder in Uşak city and determination of the visual frequency. Med-Science. 2020;9(1):26-32. doi: https://doi.org/10.5455/medscience.2019.08.9129

Jones MW, Gnanapandithan K, Panneerselvam D, Ferguson T. Chronic Cholecystitis. In: StatPearls. Treasure Island (FL): StatPearls Publishing [Internet]. 2023 [cited 2024 Mar 12]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470236/

Costanzo ML, D'Andrea V, Lauro A, Bellini MI. Acute cholecystitis from biliary lithiasis: diagnosis, mana-gement and treatment. Antibiotics (Basel). 2023;12(3):482. doi: https://doi.org/10.3390/antibiotics12030482

Jones MW, Weir CB, Ghassemzadeh S. Gallstones (Cholelithiasis). In: StatPearls. Treasure Island (FL): StatPearls Publishing [Internet]. 2024 [cited 2024 Mar 12]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459370/

Di Mauro D, Orabi A, Myintmo A, Reece-Smith A, Wajed S, Manzelli A. Routine examination of gallbladder specimens after cholecystectomy: a single-centre analysis of the incidence, clinical and histopathological aspects of incidental gallbladder carcinoma. Discov Oncol. 2021;12(1):4. doi: https://doi.org/10.1007/s12672-021-00399-5

Tinelli A, Vinciguerra M, Malvasi A, Andjić M, Babović I, Sparić R. Uterine Fibroids and Diet. Int J Environ Res Public Health. 2021;18(3):1066. doi: https://doi.org/10.3390/ijerph18031066

Giuliani E, As-Sanie S, Marsh EE. Epidemiology and management of uterine fibroids. Int J Gynaecol Obstet. 2020;149(1):3-9. doi: https://doi.org/10.1002/ijgo.13102

Yang Q, Ciebiera M, Bariani MV, et al. Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment. Endocr Rev. 2022 Jul 13;43(4):678-719. doi: https://doi.org/10.1210/endrev/bnab039. Erratum in: Endocr Rev. 2022 Jul 13;43(4):761. doi: https://doi.org/10.1210/endrev/bnac007. Erratum in: Endocr Rev. 2022 Jul 13;43(4):762. doi: https://doi.org/10.1210/endrev/bnac006

Qu Y, Chen L, Guo S, Liu Y, Wu H. Genetic liability to multiple factors and uterine leiomyoma risk: a Mendelian randomization study. Front. Endocrinol. 2023;14:1133260. doi: https://doi.org/10.3389/fendo.2023.1133260

Huseman-Plascencia LA, Villa-Villagrana F, Ballesteros-Manzo A, Baptista Rosas RC, Mercado-Ses-ma AR, Arámbula-Chavolla MI. Body mass index and vitamin D as risk factors for the development of uterine leiomyomas in Mexican women. Journal of Endometrio-sis and Pelvic Pain Disorders. 2022;14(1):14-8. doi: https://doi.org/10.1177/22840265211065226

GBD 2019 Benign Prostatic Hyperplasia Collaborators. The global, regional, and national burden of benign prostatic hyperplasia in 204 countries and territories from 2000 to 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Healthy Longev. 2022;3(11):e754-e776. doi: https://doi.org/10.1016/S2666-7568(22)00213-6

Cannarella R, Condorelli RA, Barbagallo F, La Vignera S, Calogero AE. Endocrinology of the Aging Prostate: Current Concepts. Front Endocrinol (Lausanne). 2021;12:554078. doi: https://doi.org/10.3389/fendo.2021.554078

Moussa M, Papatsoris A, Chakra MA, Fares Y, Dellis A. Lower urinary tract dysfunction in common neurological diseases. Turk J Urol. 2020;46(Supp 1):S70-S78. doi: https://doi.org/10.5152/tud.2020.20092

Park S, Lee KS, Choi M, Lee M. Factors associated with quality of life in patients with benign prostatic hyperplasia, 2009-2016. Medicine (Baltimore). 2022;101(36):e30091. doi: https://doi.org/10.1097/MD.0000000000030091

Wang YB, Yang L, Deng YQ, et al. Causal relationship between obesity, lifestyle factors and risk of benign prostatic hyperplasia: a univariable and multi-variable Mendelian randomization study. J Transl Med. 2022;20:495. doi: https://doi.org/10.1186/s12967-022-03722-y

Загрузки

Опубликован

2024-10-16

Как цитировать

1.
Todorova SA. The incidence of benign and malignant tumors among adults with long-term physical disabilities. Med. perspekt. [Интернет]. 16 октябрь 2024 г. [цитируется по 23 ноябрь 2024 г.];29(3):166-75. доступно на: https://journals.uran.ua/index.php/2307-0404/article/view/313671

Выпуск

Раздел

CLINICAL MEDICINE